3-Hydroxy-2-methylpyridine

3-Hydroxy-2-methylpyridine, Chinese name 3-hydroxy-2-methylpyridine, is an organic compound, which has a wide range of uses and plays an important role in many fields such as chemical industry, medicine, materials, etc.
In the field of chemical synthesis, it is a key intermediate. It can build more complex organic molecular structures through specific chemical reactions. For example, by virtue of its hydroxyl and pyridine ring activity, it can react with halogenated hydrocarbons to form new nitrogen-containing organic compounds. Such compounds are often important raw materials for the synthesis of fine chemicals, such as fragrances, dyes, etc. The presence of the pyridine ring endows the molecule with unique electronic properties and stability, so in the synthesis of dyes, the color and fastness of dyes can be optimized.
In the field of medicine, 3-hydroxy-2-methylpyridine also plays an important role. Due to its structural properties, it has certain biological activities and can be used as a lead compound for drug development. Studies have shown that its derivatives have potential effects on some disease targets, such as in the study of anti-tumor drugs, it shows inhibitory effects on the growth and proliferation of specific tumor cells. By modifying and optimizing its structure, it is expected to obtain new drugs with better efficacy and less side effects.
In the field of material science, it can be used to prepare functional materials. Such as coordination with metal ions to build metal-organic framework materials (MOFs). Such materials have great potential in gas adsorption and separation, catalysis and other fields due to their unique structures and properties. 3-Hydroxy-2-methylpyridine as a ligand can regulate the structure and function of MOFs, such as changing their pore size and surface properties, to meet different application requirements.

3-Hydroxy-2-methylpyridine is one of the organic compounds. Its physical properties are unique and have the following characteristics.
Looking at its properties, it is mostly crystalline solid under normal conditions, which is caused by the orderly arrangement of intermolecular forces. Its melting point is quite important, about a specific temperature range. The characteristics of this melting point are crucial in the identification and purification of compounds. Due to the different melting points of different compounds, its authenticity and purity can be distinguished.
Furthermore, the solubility of this substance is also considerable. In common organic solvents, such as ethanol, acetone, etc., there is a certain solubility. This is due to the presence of hydroxyl groups and methyl groups in the molecular structure, which affects the interaction between them and solvent molecules. Hydroxyl groups have a certain polarity and can interact with the polar parts of organic solvents to form hydrogen bonds, so they can dissolve in them. In water, because its polarity is not extremely strong, the solubility is relatively limited.
Its boiling point is also an important physical property. Under a specific pressure, when it reaches a certain temperature, it boils. This boiling point value reflects the strength of the intermolecular force. A higher boiling point indicates that the intermolecular force is strong, and more energy needs to be supplied to make it into a gaseous state.
In addition, the color state of 3-hydroxy-2-methylpyridine also needs to be paid attention to. Pure people are often colorless or nearly colorless, but if they contain impurities, the color may change. This change in color state can give a preliminary indication of its purity.
From the above, the physical properties of 3-hydroxy-2-methylpyridine, such as melting point, solubility, boiling point, color state, etc., are of great significance in chemical research, industrial production and related fields. It is the basis for in-depth understanding and rational application of this substance.

3-Hydroxy-2-methylpyridine is an organic compound with unique chemical properties. It is active and can participate in many chemical reactions.
First, because it contains hydroxyl groups and has certain acidity, hydroxyl hydrogen can be dissociated under suitable conditions, and can react with bases to form corresponding salts. In case of strong bases such as sodium hydroxide, hydroxyl hydrogen will combine with hydroxide to form water and the corresponding 3-hydroxy-2-methylpyridine sodium salt.
Secondly, the pyridine ring system gives it aromaticity, and the distribution of π electron cloud makes the pyridine ring relatively stable, but it also makes it prone to electrophilic substitution. Under appropriate catalyst and reaction conditions, halogenation reagents, nitrogenation reagents, etc. can attack the pyridine ring and introduce substituents at specific positions. Taking the bromine reaction as an example, in the presence of an appropriate catalyst, bromine can replace the hydrogen atom at a specific position on the pyridine ring.
Furthermore, the hydroxyl group, as an active functional group, can participate in the esterification reaction. When coexisted with a suitable acid or anhydride, under the action of the catalyst, the hydroxyl group will esterify with the carboxyl group of the acid to form an ester compound.
In addition, the compound can also participate in the redox reaction. The hydroxyl group can be oxidized to a carbonyl group or a higher valence oxide under the action of a suitable oxidizing agent. At the same time, the electron cloud distribution on the pyridine ring may also be changed due to redox conditions, thus affecting the reactivity and properties of the whole molecule.
In short, 3-hydroxy-2-methylpyridine exhibits a variety of chemical reactivity in the field of organic synthesis due to the characteristics of hydroxyl and pyridine rings in its structure. It can be used to prepare various organic compounds and has important application value in many fields such as medicinal chemistry and materials science.

For the synthesis of 3-hydroxy-2-methylpyridine, there are many paths to follow. First, it can be obtained from the oxidation reaction of 2-methylpyridine. In this method, suitable oxidants, such as hydrogen peroxide, potassium permanganate, etc., are often used to oxidize specific positions on the pyridine ring of 2-methylpyridine, and then hydroxyl groups are introduced. It is necessary to pay attention to the precise control of the reaction conditions, such as temperature, pH, etc., because these factors have a great influence on the selectivity and yield of the reaction.
Second, a suitable nitrogenous and oxygenated organic compound is used as the starting material and synthesized through a multi-step reaction. For example, compounds containing methyl and pyridine ring structures can be selected. The pyridine ring is first modified by a specific reaction, and then hydroxyl groups are introduced. This process may involve various reaction types such as nucleophilic substitution and addition. Careful operation is required in each step of the reaction to ensure the smooth progress of the reaction and the purity of the product.
Third, the catalytic synthesis method is also an important way. With a specific catalyst, under suitable reaction conditions, the reactants are converted to 3-hydroxy-2-methylpyridine. The key to this method is to find a catalyst with high efficiency and good selectivity to improve the reaction efficiency and product yield, and the stability and recycling of the catalyst also need to be considered thoroughly. In the process of synthesis, it is necessary to carefully observe the details of each reaction step and precisely adjust the reaction conditions to obtain high-purity 3-hydroxy-2-methylpyridine.

The price of all kinds of products in the market varies from time to time, and also varies with changes in quality and supply and demand. As for 3-Hydroxy-2-methylpyridine, its market price range is difficult to determine with certainty.
The price of the product is determined by many factors. First, the difficulty of production. If the preparation method is difficult and difficult, and exquisite craftsmanship and rare raw materials are required, the price will be high; if the preparation technique is simple and the raw materials are easy to obtain, the price may be slightly lower. Second, the state of supply and demand is also. If there are many users, there are many who want it, but there are few producers, and the supply is not enough to meet the demand, the price will rise; if there are few users and there are too many producers, the price will drop. Third, the quality is also different. Those with excellent quality should be priced high; those with inferior quality should be priced poorly.
However, according to past transactions and industry reports, the price of 3-Hydroxy-2-methylpyridine ranges from a few yuan to tens of yuan per gram. There are also differences in batch size. For those with large batches, the price per gram may be slightly reduced; for those with small batches, the price per gram may be slightly increased.
However, the market conditions are constantly changing, and this is only a rough estimate. If you want to know the exact price, you need to consult various suppliers and observe their current quoted prices before you can obtain a more accurate price range.