3 Hydroxy 2 Methyl 5 Phosphonooxy Methyl 4 Pyridinecarboxaldehyde
pyridine pyrrole pyrazine piperidine piperazine

3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde

    Specifications

    HS Code

    720636

    Chemical Formula C7H10NO7P
    Molar Mass 253.13 g/mol
    Appearance Solid (predicted)
    Solubility In Water Moderate (predicted)
    Boiling Point Decomposes (predicted)
    Melting Point 140 - 145 °C (predicted)
    Density 1.69 g/cm³ (predicted)
    Acidity Pka 2.34 (for phosphonic acid group, predicted)
    Chirality Achiral
    Functional Groups Hydroxy, methyl, phosphonooxy - methyl, pyridine - carboxaldehyde

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    Frequently Asked Questions

    As a leading 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 3-Hydroxy-2-methyl-5- ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde?
    This is the name of an organic compound. According to its name, its chemical structure can be deduced as follows:
    The core of this compound is a pyridine ring. At the 3rd position of the pyridine ring, it is connected with a hydroxyl group (-OH); at the 2nd position, it is connected with a methyl group (-CH 🥰); at the 5th position, it is connected with a special group. This group is connected by a methylene group (-CH 🥰 -) to a phosphoxy group (-O-PO 🥰 H 🥰) and an aldehyde group (-CHO).
    The basic structure of its pyridine ring provides the basis for the stability and reactivity of the whole molecule. The 3-position hydroxyl group is hydrophilic and can participate in hydrogen bond formation and various chemical reactions, such as esterification and oxidation. The methyl group of the 2 position, although a simple alkyl group, has an impact on the spatial structure of the molecule and the distribution of electron clouds, changing the physical and chemical properties of the molecule. The group of the 5 position is particularly critical. The existence of the aldehyde group is highly reactive and can participate in many organic synthesis reactions, such as nucleophilic addition; while the phosphoroxy group imparts a certain degree of acidity and hydrophilicity to the molecule, and may play an important role in the phosphorylation process in vivo.
    In summary, this compound has unique chemical properties and potential application value in organic synthesis, biochemistry and other fields due to the synergistic effect of various groups.
    What are the physical properties of 3-Hydroxy-2-methyl-5- ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde?
    3-Hydroxy-2-methyl-5- ([phosphoryloxy] methyl) -4-pyridine formaldehyde, this is an organic compound. Its physical properties are unique, let me tell them one by one.
    Looking at its morphology, under room temperature and pressure, it is mostly in a solid state, but it is not absolute, or it varies depending on the purity and preparation conditions. Its color is usually white to light yellow powder, uniform and pure.
    When it comes to solubility, this substance exhibits a certain solubility in water. This is because the molecular structure contains polar groups such as hydroxyl groups and aldehyde groups, which can form hydrogen bonds with water molecules, so it can be dispersed in water to a certain extent. However, it has poor solubility in non-polar organic solvents, such as benzene and n-hexane. Due to its strong polarity as a whole, the forces between molecules and non-polar solvents are weak, making it difficult to miscible with each other.
    Melting point is also one of the important physical properties. The relatively high melting point of this compound is due to the existence of strong forces between molecules, such as hydrogen bonds, van der Waals forces, etc. These forces make the molecules tightly bound, and high energies are required to disintegrate the lattice structure and convert from solid to liquid. The exact melting point value needs to be determined by professional experiments, due to differences in different literature and experimental conditions.
    In addition, this density also has its own characteristics. Although the exact value varies depending on the determination method and conditions, its density is similar to that of common organic compounds. This density characteristic makes it exhibit corresponding behavior in a specific environment, during the separation and sedimentation of the mixture.
    In summary, the physical properties of 3-hydroxy-2-methyl-5- ([phosphoryloxy] methyl) -4-pyridine formaldehyde are determined by its molecular structure, which has a profound impact on its application in chemical and pharmaceutical fields.
    What are the main uses of 3-Hydroxy-2-methyl-5- ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde?
    3-Hydroxy-2-methyl-5- ([phosphoryloxy] methyl) -4-pyridyl formaldehyde, which is a chemical substance. It has a wide range of uses and is often a key intermediate in the synthesis of drugs in the field of medicinal chemistry.
    The way of Guofu's pharmaceutical creation, many new drug development needs to use this as the starting material. Because of its unique structure, it contains active groups such as hydroxyl groups, aldehyde groups and phosphoryloxy groups, which can build complex molecular structures through chemical reactions, so it plays an important role in the design of drug molecules. With their characteristics, chemists have carefully crafted and derived compounds with specific pharmacological activities, either antibacterial, anti-inflammatory, or have a regulatory effect on specific disease targets, laying the foundation for conquering diseases and benefiting the common people.
    In the field of materials science, it also has extraordinary performance. With its active groups, it can participate in the surface modification reaction of materials. Through a specific process, it is introduced into the surface of materials to impart new properties such as antimicrobial and biocompatibility to materials. For example, in the surface modification of medical implant materials, it can reduce the immune rejection of the body, improve the properties of materials, and expand the application scenarios of materials.
    In addition, in the field of organic synthetic chemistry, it serves as a key synthetic building block, providing the possibility for the construction of complex pyridine compounds. Organic chemists use various synthetic strategies to build a diverse structure of pyridine derivatives, enrich the library of organic compounds, inject vitality into the development of organic synthetic chemistry, and promote the continuous advancement of chemical science to explore the unknown chemical world.
    What are the synthesis methods of 3-Hydroxy-2-methyl-5- ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde?
    3 - Hydroxy - 2 - methyl - 5 - ([phosphonooxy] methyl) - 4 - pyridinecarboxaldehyde, this is an organic compound, and its synthesis method has been explored by many scholars in the past.
    To synthesize this compound, you can first take an appropriate pyridine derivative as the starting material. Find a pyridine containing a suitable substituent and modify it under specific reaction conditions. Halogen atoms can be introduced at specific positions in the pyridine ring by halogenation reaction to lay the foundation for the subsequent reaction. This halogenation reaction requires fine regulation of reaction temperature, reaction time and the ratio of reactants to obtain ideal yields and selectivity. < Br >
    Then, a phosphoroxy methyl group is introduced. Phosphorus reagents can be used to combine phosphorus reagents with halogen-containing pyridine derivatives through nucleophilic substitution reaction. In this step, the choice of reaction solvent is crucial, and its properties such as polarity and solubility will affect the reaction process. Or polar aprotic solvents can be used to promote the activity of nucleophiles and make the reaction easier.
    Furthermore, hydroxy and methyl groups are constructed. The introduction of hydroxyl groups can convert specific groups into hydroxyl groups through suitable oxidation reactions. The addition of methyl groups can use methylating reagents to achieve methyl substitution under appropriate alkaline conditions. The reaction sequence of the two also needs to be carefully considered, and different orders may lead to differences in products.
    Synthesis of 3-Hydroxy-2-methyl-5 - ([phosphonooxy] methyl) - 4 - pyridinecarboxaldehyde is a complicated process, and it is necessary to have a deep understanding of the many reaction mechanisms and conditions of organic synthesis in order to obtain this compound in an appropriate way.
    3-Hydroxy-2-methyl-5- ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde what are the precautions during use?
    3 - Hydroxy - 2 - methyl - 5 - ([phosphonooxy] methyl) - 4 - pyridinecarboxaldehyde, this is a complex organic compound. During use, many matters need to be paid attention to.
    Bear the brunt and safety is of paramount importance. Due to its unique chemical structure, it may be toxic and irritating. When operating, be fully armed and wear protective clothing, gloves and goggles to prevent the substance from contacting the skin and eyes. If you come into contact, rinse with plenty of water immediately and seek medical attention quickly according to the specific situation.
    Furthermore, stability cannot be ignored. This compound is quite sensitive to environmental factors such as temperature, humidity and light. It should be stored in a cool, dry and dark place, away from heat and fire to prevent deterioration or dangerous reactions. During use, minimize its exposure to the external environment.
    Repeat, accurate dose control is indispensable. In view of its critical role in the reaction, the amount of dosage will have a significant impact on the reaction result. Before use, it is necessary to carefully measure and calculate with the help of precise instruments to ensure that the dose is accurate to achieve the desired reaction effect.
    In addition, the chemical reaction mechanism involved in this compound is complicated. Before use, you should have a thorough understanding of the relevant chemical reactions, be familiar with the reaction conditions, the proportion of reactants and possible side reactions. In this way, you can handle it freely during use, ensure scientific and reasonable operation, and avoid unexpected situations.
    In short, when using 3 - Hydroxy - 2 - methyl - 5 - ([phosphonooxy] methyl) - 4 - pyridinecarboxaldehyde, safety, stability, dosage and reaction mechanism should be treated with caution, and must not be taken lightly to avoid adverse consequences.