3-Hydroxy-2-cyanopyridine

3-Hydroxy-2-cyanopyridine is an organic compound. It is basic, because the pyridine ring nitrogen atom has unshared electron pairs, it can accept protons. Under specific conditions, it is weakly basic and can form salts with acids.
This compound contains hydroxyl groups, which cause it to have a certain hydrophilicity. Hydroxyl groups can participate in the formation of hydrogen bonds, which has a great influence on its solubility, melting point, boiling point and other physical properties. Due to the existence of hydroxyl groups, it has a certain solubility in water or polar organic solvents.
Cyanyl is a strong electron-absorbing group, which has a significant impact on the distribution of electron clouds in the pyridine ring. The electron cloud density on the ring decreases, which decreases its electrophilic substitution reaction activity, especially on the pyridine ring, the electrophilic substitution reaction tends to occur at a relatively high electron cloud density position. At the same time, cyanyl groups can participate in a variety of chemical reactions, such as hydrolysis reactions. Under the catalysis of acids or bases, cyanyl groups can be converted into carboxyl groups; they can also participate in nucleophilic addition reactions.
Its chemical properties are active, and it is widely used in the field of organic synthesis. It can be used as an intermediate to construct more complex organic molecular structures through various reactions, which is of great significance in pharmaceutical chemistry, materials science and other fields.

3-Hydroxy-2-cyanopyridine has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can be converted through various reactions to produce compounds with specific pharmacological activities, which are used in the development of drugs for the treatment of various diseases such as cardiovascular diseases and nervous system diseases.
In the field of pesticides, 3-hydroxy-2-cyanopyridine also plays an important role. Through a series of chemical reactions, pesticide products with high insecticidal, bactericidal or herbicidal properties can be synthesized. These pesticides can effectively resist crop diseases and pests, improve crop yield and quality, and are more environmentally friendly than some traditional pesticides.
Furthermore, in the field of materials science, 3-hydroxy-2-cyanopyridine can participate in the preparation of materials with specific functions. For example, in the synthesis of some organic optoelectronic materials, it can be used as a key structural unit to endow the material with unique optical and electrical properties, which contributes to the development of new display technologies and optoelectronic devices.
In organic synthesis chemistry, 3-hydroxy-2-cyanopyridine is often used as a reaction substrate or intermediate. Chemists can use various organic reactions based on its structure to construct more complex organic molecular structures, expand the boundaries of organic synthesis, and provide a foundation for the creation of new compounds. From this perspective, 3-hydroxy-2-cyanopyridine plays an important role in many fields and is of great significance to the development of many industries.

The synthesis of 3-hydroxy-2-cyanopyridine has been studied by many talented people since ancient times. One method is to use pyridine derivatives as starting materials and skillfully transform them through specific chemical reactions. For example, first take a suitable pyridine substrate and introduce halogen atoms at a specific position in the pyridine ring through a halogenation reaction. This halogenation step requires careful control of the reaction conditions, such as temperature, reaction time, and proportion of reactants, in order to achieve the ideal halogenation effect.
Next, the halogen-containing pyridine derivative meets the cyanide reagent. This process is similar to two dancers dancing together on stage. It is necessary to choose a suitable solvent and catalyst to effectively combine the two and successfully introduce cyanide groups. In this step, the polarity of the solvent and the activity of the catalyst all have a great impact on the reaction process, and it is difficult to achieve expectations if you are not careful.
Then the product containing cyanide groups is added with hydroxyl groups in the appropriate position through a fine hydroxylation reaction, and then 3-hydroxy-2-cyanopyridine is obtained. This hydroxylation reaction is like adding the finishing touch to a beautiful work of art. It is necessary to precisely control the reaction conditions in order to achieve a good work.
Another method is to use other compounds as starting materials, through multiple steps of reaction, to ingeniously construct a pyridine ring, and introduce cyanyl and hydroxyl groups at the same time. This path is like building a delicate pavilion, and each step needs to be carefully designed. First, the prototype of the pyridine ring is constructed by an ingenious reaction, and then the required cyanyl and hydroxyl groups are introduced in turn. In each step of the reaction, many factors such as the activity and selectivity of the reactants need to be considered. If there is a slight error, it will fall short.
Furthermore, there are also those who use some special chemical reaction mechanisms to synthesize this compound through unique reaction routes. This is a different approach. Although few people have tried it, if it succeeds, it will definitely show the wonder and charm of chemistry.

3-Hydroxy-2-cyanopyridine is a chemical substance. During storage and transportation, there are a number of important items that need to be paid attention to.
First word storage. This substance should be stored in a cool, dry and well ventilated place. Because if it is in a warm and humid place, its properties may change. Cover warm heat can promote the rate of chemical reactions, humid gas may interact with the like, damaging its quality. And it needs to be kept away from fires and heat sources to prevent unexpected explosions. Because it may have certain chemical activity, it may be dangerous when exposed to open flames or hot topics. It should also be stored separately from oxidants, acids, bases, etc., and must not be mixed. When these substances meet with 3-hydroxy-2-cyanopyridine, they are prone to chemical reactions, or cause the formation of harmful substances, or cause violent reactions, endangering safety.
Next talk about transportation. When transporting, make sure that the container does not leak, collapse, fall, or damage. Because if it leaks, it not only pollutes the environment, but also leaks or interacts with external substances, causing danger. The means of transportation must also be clean and dry, and there should be no residue that reacts with it. During transportation, it should be protected from exposure to the sun, rain, and high temperature. If it is summer, it is necessary to choose a cool time for transportation, or to insulate the means of transportation. The escort personnel should also be familiar with their characteristics and emergency handling methods. If there is any abnormality on the way, they can respond in time to ensure the safety of transportation.

The market price range of 3-hydroxy-2-cyanopyridine is difficult to determine with certainty. The price of this chemical often varies due to various factors, such as supply and demand in the city, manufacturing costs, quality grades, number of transactions and regional differences.
Looking at the past market, its price fluctuations are quite obvious. When demand is strong and supply is limited, prices tend to rise; if production capacity increases sharply, supply exceeds demand, prices may fall. And different quality grades have different prices, and high purity prices are often higher than ordinary ones.
The number of transactions also affects its price. Buyers in bulk may get preferential prices due to large quantities; small purchases, unit prices may be higher. Furthermore, different regions have different prices due to logistics costs and market competition. In places with sufficient supply and intense competition, the price may be relatively low; in remote or scarce supply, the price may be high.
To know the exact market price, you need to carefully check the real-time quotation of the chemical raw material trading platform, or consult the relevant chemical product suppliers to obtain the current exact price range.