3-Formyl-6-methoxypyridine

3-formyl-6-methoxypyridine is also an organic compound. It has a wide range of uses and is often a key intermediate in the creation of new drugs in the field of medicinal chemistry. Due to its unique chemical structure, it can participate in a variety of chemical reactions, laying the foundation for the construction of complex drug molecules.
In materials science, it also plays an important role. Or it can be used to prepare organic materials with special properties, such as those with specific optical and electrical properties. Because it can endow materials with unique structures and affect the physical and chemical properties of materials, so as to meet the special needs of different fields for material properties.
In the field of organic synthesis chemistry, 3-formyl-6-methoxypyridine is an important starting material. Chemists can modify and derive its structure through various reactions, such as nucleophilic addition and condensation, to obtain organic compounds with rich structures and different functions, thereby expanding the scope of organic synthesis and providing possibilities for the development of novel organic molecules. In short, this compound has shown value in many fields and promotes the sustainable development of related disciplines and industries.

3-Formyl-6-methoxypyridine is one of the organic compounds. Its physical properties are particularly important and it is widely used in various fields of chemistry.
First of all, its appearance, at room temperature, is mostly white to light yellow solid, with fine texture. This appearance feature can be an important basis for preliminary identification and operation.
When talking about the melting point, it is about 64-66 ° C. The exact value of the melting point varies depending on the purity of the material. The melting point of pure people is more precise and fixed. If impurities are contained, the melting point may decrease and the melting range will also increase. This melting point property is of great significance when purifying and identifying the compound, and can be determined according to the melting point to determine its purity.
Boiling point, about 274.9 ° C. The boiling point reflects the temperature conditions for a substance to change from a liquid to a gaseous state. Knowing the boiling point can be a key parameter in operations such as distillation and separation to assist chemists in separating the compound from other substances and achieving the purpose of purification.
In terms of solubility, it is slightly soluble in water. Water is the source of all things and the medium for many chemical reactions. The slightly soluble nature of 3-formyl-6-methoxypyridine in water determines the degree and manner of its participation in aqueous reactions. However, it has good solubility in common organic solvents such as ethanol, chloroform, dichloromethane, etc. This property makes it possible to choose a suitable organic solvent to dissolve it according to the reaction requirements and promote the reaction.
In addition, the density of the compound also has its own characteristics. Although the exact density value varies slightly due to measurement conditions, it is roughly within a certain range. The value of density is an indispensable parameter when measuring and calculating the amount of the compound.
In summary, the physical properties of 3-formyl-6-methoxypyridine, such as appearance, melting point, boiling point, solubility, and density, are interrelated and are important factors for chemical research, organic synthesis, and related industrial production, and play a key guiding role in its application and operation.

The synthesis method of 3-formyl-6-methoxypyridine has been known for a long time. One method is to use 6-methoxypyridine-3-carboxylic acid as the starting material. First, the carboxylic acid is heated with dichlorosulfoxide, and the two are mixed. The carboxyl group of the carboxylic acid is converted into an acyl chloride. This reaction needs to be carried out at an appropriate temperature and time to ensure the completion of the reaction. The resulting acyl chloride product is then carefully reduced with a suitable reducing agent, such as lithium aluminum hydride or sodium borohydride, etc., so that the acyl chloride can be converted into the corresponding aldehyde group, that is, 3-formyl-6-methoxypyridine. In this process, the amount of reducing agent, the temperature and time of the reaction need to be carefully controlled, otherwise side reactions will easily occur and the product will be impure.
Another method is to use 6-methoxy-3-methylpyridine as the starting material. First, it is oxidized to a carboxyl group with an appropriate oxidizing agent, such as potassium permanganate or potassium dichromate, under specific reaction conditions, to obtain 6-methoxy pyridine-3-carboxylic acid. Then, according to the previous description, the carboxylic acid is converted into acyl chloride, and then the target product is reduced. This path has a little more steps, but the raw material is easier to obtain.
There is also a method of metal catalysis. Using 6-methoxypyridine as the substrate, under the catalysis of suitable metal catalysts such as palladium and copper, and with suitable formylation reagents, such as the mixed system of carbon monoxide and alcohol, under specific pressure and temperature conditions, the formyl group can be directly introduced to obtain 3-formyl-6-methoxypyridine. Although this method has the advantages of atomic economy, it requires high reaction equipment and conditions.
All kinds of synthesis methods have their own advantages and disadvantages. According to actual needs, consider the cost of raw materials, the difficulty of reaction, the purity of the product and other factors, and choose the best one.

The price of 3-formyl-6-methoxypyridine in the market is difficult to determine. The change in its price is related to many reasons.
First, whether the quality is pure or not, it matters a lot. If the quality is high and pure, the price will be high; if there are other things, the purity is insufficient, and the price may drop slightly.
Second, the amount of production is also the main reason. If there is more production, the supply will exceed the demand, and the price may decrease; if there is less production, the demand will exceed the supply, and the price will increase.
Third, the amount purchased also has an impact. If the purchase quantity is large, there may be a discount; if the purchase quantity is small, the price may continue as usual.
According to past transactions, the price per gram may be between tens of yuan and hundreds of yuan. However, this is only an approximate number, and the market situation changes. The actual price depends on the current situation. To know the exact price, you can consult the chemical material merchant or the platform for chemical product trading to get the current real price.

3-Formyl-6-methoxypyridine is a kind of organic compound. Its storage conditions are crucial, which is related to the stability and quality of this substance. According to the concept of "Tiangong Kaiwu", everything follows the law of nature, and material storage should also go with its own nature.
This compound is more sensitive to light and air. Light, such as direct sunlight, can easily cause photochemical reactions, damaging its structure and properties. It should be stored in a dark place, such as in dark bottles, or in a dark warehouse. In air, both oxygen and moisture are unfavorable factors. Oxygen can cause oxidation, moisture can cause hydrolysis and other reactions. Therefore, it needs to be sealed for storage, and airtight containers can be used to prevent air intrusion.
Temperature is also critical. Excessive temperature can accelerate its chemical reaction rate and promote decomposition or deterioration; too low temperature, although it may slow down the reaction, may cause it to crystallize and solidify, etc., affecting access and performance. Generally speaking, it should be stored in a cool place, preferably 2-8 ° C. This temperature range can better maintain its stability, just like the mildness of the natural season, so as not to be too hot or cold and damage.
In addition, the storage place should be kept away from fire, heat sources and other chemically active substances. Fire and heat sources can cause fires or cause them to react violently; and coexist with active substances, or cause them to deteriorate due to interaction. All these are the important principles for the storage of 3-formyl-6-methoxypyridine, and according to this, it must be properly preserved.