3 Fluoro 5 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Fluoro-5-chloropyridine

    Specifications

    HS Code

    500962

    Chemical Formula C5H3ClFN
    Appearance colorless to light yellow liquid
    Boiling Point 155 - 157 °C
    Melting Point N/A
    Density 1.352 g/cm³
    Flash Point 57 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Pka N/A
    Vapor Pressure N/A
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy 3-Fluoro-5-chloropyridine in China?
    As a trusted 3-Fluoro-5-chloropyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Fluoro-5-chloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-fluoro-5-chloropyridine?
    The main use of the 3-5-sea is to pass through the ocean, and it is also important for prevention.
    Since ancient times, people have observed the convenience of water transportation, rivers can pass through the region, and the ocean contains more commerce. 3-5-The sea flows to it, forming a large waterway, and ships can be carried on it, and the special features of various places can be sent to other places. For example, the merchant ships of the ocean, such as, porcelain, etc. Coastal waterways are important, but they can be passed and fortresses to resist foreign invasion. Ships on the sea patrol and guard, and protect the boundaries of the sea, so that the sea can be easily accessed. In case of trouble, these waters can also be moved and sheltered for a while, and they can be the master of the sea.
    And the nature of water is soft, and the boat can also capsize when it can be built. 3-5-The sea is for its own benefit, but it also needs to be well managed. Dredging rivers to prevent silting; building embankments to prevent floods. In this way, it can be used by the people forever and be used for the well-being of the world. In this way, 3-5-The sea is of paramount importance in terms of its safety, prevention and people's livelihood. It is the cause of the decline of the family and the well-being of the people.
    What are the physical properties of 3-fluoro-5-chloropyridine?
    3-River-5-Sea-facing objects have different physical properties and each has its own characteristics. The details are as follows:
    River, the water flow often follows the river channel, and its source is mostly from the mountain stream valley, which converges and trickles. The color of the river water, whether clear or turbid, depends on the geology of the basin and the condition of water and soil. In the lush mountains and lush vegetation, the river water is more clear and the sediment content is less; if it passes through the loess land and is initialized by heavy rain, the water color will turn yellow and the sand will fall. Its water temperature changes with the seasons, warm in summer and cool in winter. However, compared with the surface temperature, the change is slightly slower, which has a certain ability to adjust the climate. The speed of the river water varies depending on the terrain drop. In the mountains and valleys, the flow speed is rapid, which can generate surging momentum and has strong kinetic energy; in the vastness of the plain, the flow speed gradually slows down and the water waves are long.
    For the sea, the waters are vast, and its water is salty, which is caused by the dissolution of many minerals over time. The color of the sea water is often blue, but in the coastal areas, or due to the influence of sediment, plankton, etc., it is yellow-green. The sea temperature is generally higher in low latitudes, and lower in high latitudes, and the water temperature in the depths is constant and cold. The sea surface is affected by monsoons, ocean currents, etc., and the waves are undulating, sometimes huge waves, majestic. Ocean currents are like invisible hands, driving large-scale flow of sea water, affecting climate and marine ecology. The change of tides is also a significant feature of the sea. Affected by the attractive forces of the sun and the moon, it fluctuates regularly, twice a day, between the ebb and flow of tides, and the coastline landscape changes endlessly.

    River and sea, although both are the convergence of water, have different physical properties. The river is mainly fresh water and runs according to the river channel; the sea is the source of saltwater, which is vast and boundless. The two are related to each other. Rivers rush into the sea, bringing fresh water and nutrients to the sea, shaping the offshore ecology; the tides and currents of the sea also have a profound impact on the climate and geography of the riverside area, and together form a wonderful landscape and ecosystem of nature.
    What are the chemical properties of 3-fluoro-5-chloropyridine?

    3 - It is strong in nature, like a fire, and when things are destroyed, they cannot be destroyed. It can cause many things to react violently, and it can release a lot of force, just like thunder. This property makes it useful in smelting things. It can melt things, melt things easily, and help craftsmen make good tools.
    5 - It is soft in nature, like water. It has the ability to absorb, like a magnet, quietly gather things. It is also good at dissolving other things, so that they can be transformed into one, just like a valley, inclusive of things. In the stone matching the stone, the stone can be mixed with the stone, so that it complements each other and has a miraculous effect.
    Then the two meet, and the life is wonderful. 3 - The intensity of the strong, when met with 5 - the softness of the soft, like a sudden plunge into the swamp, the softness is mixed. The opposite is neither the intensity of the blind nor the total peace, but the birth of new things. This new thing is both effective, or it can be used as an exquisite and durable device, or it can be used as a new way on the stone to heal the disease.
    In this way, 3 - 5 - The transformation of the nature of the stone, each has its own strengths and weaknesses, and each has its own advantages and benefits. The intersection of the two makes it even more possible to hide limited possibilities. It is up to the wise to explore in depth, so as to use it for the benefit of the world.
    What are the synthesis methods of 3-fluoro-5-chloropyridine?
    To prepare 3-alkenyl-5-aldehyde, there are various methods.
    First, it can be obtained by oxidation of the corresponding alcohol. Take a suitable alcohol, choose an appropriate oxidizing agent, such as pyridine-sulfur trioxide complex (Py · SO 🥰), in a suitable solvent, such as dichloromethane, and control it at a moderate temperature to oxidize the alcohol hydroxyl group to an aldehyde group, and preserve the integrity of the alkenyl bond. In this process, it is necessary to observe the reaction conditions to prevent the excessive oxidation of the alkenyl bond.
    Second, the functional group transformation of the carbon-carbon double bond can be used. First, an olefin containing a suitable substituent is prepared, and an organometallic reagent, such as a Grignard reagent, reacts with the corresponding halogenated hydrocarbon to introduce the desired carbon chain fragment. Then, through an oxidation step, the carbon at a specific position is converted into an aldehyde group. For example, an allyl halogen and magnesium are first prepared into a Grignard reagent, and then reacted with a suitable carbonyl compound, and then mildly oxidized to obtain the target product.
    Third, take the condensation reaction as the path. Between aldose and aldehyde or between aldehyde and ketone, under alkali catalysis, a hydroxyaldehyde condensation reaction is carried out. For example, in a dilute alkali solution, acronaldehyde and acetaldehyde are used as raw materials, and the condensation occurs at low temperature to generate β-hydroxyaldehyde. After dehydration, 3-ene-5-aldehyde can be obtained. The concentration of the base, the reaction temperature and time are all key, and must be carefully regulated to increase the yield and purity of the product.
    Fourth, use the Diels-Alder reaction. Select the appropriate diene body and the biene-friendly body, and the two react by cycloaddition to construct a six-membered cyclic structure. After appropriate ring opening and functional group transformation, the target 3-ene-5-aldehyde is obtained. This reaction requires attention to the activity matching of the diene and the diene-philanthropic body, and the optimization of the reaction conditions, so that the reaction can proceed smoothly.
    All these methods have their own advantages and disadvantages. According to the availability of raw materials, the difficulty of reaction, the yield and the purity of the product, etc., the most suitable method is selected to produce 3-ene-5-aldehyde.
    What is the price range of 3-fluoro-5-chloropyridine in the market?
    I have heard your inquiry, but it is the price range of three oils and five gases in the market. However, the market situation is changeable, and the price also changes with many factors, such as supply and demand conditions, political orientation, international trends, cost movements, etc. Therefore, it is difficult to determine the fixed price range.
    Looking at the city in the past, oil prices may not be smooth due to geopolitical disputes, and prices will rise; or due to the emergence of new sources, supply exceeds demand, and prices will be depressed. As for gas prices, they will also rise in winter due to strong heating demand; or due to abundant gas fields, production capacity will increase greatly, and prices will decline.
    And different places have different prices. In a prosperous city, the demand is large and the supply is limited, and the price may be high; in a remote area, the supply needs to be slow and sufficient, and the price may be low. And when trading is different, the price is also different. Day and night change, week and month change, and the price may move.
    Although it is difficult to know the exact extent, if you want to know the approximation, you can use the city's newspapers, industry analysis, or the price situation under the observation of the situation to make a guess. However, the market is unpredictable, that is, the best analysis, it is also difficult to fully predict the direction of the price. Only by closely observing the state of the city and knowing the change of the situation can you know the approximate movement of the price.