3 Fluoro 4 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Fluoro-4-trifluoromethyl pyridine

    Specifications

    HS Code

    174476

    Chemical Formula C6H3F4N
    Molecular Weight 165.09
    Appearance Colorless to light yellow liquid
    Boiling Point 126 - 128 °C
    Density 1.37 g/cm³
    Solubility Soluble in organic solvents like ethanol, ether
    Flash Point 37 °C
    Logp Around 2.5

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    General Information
    Where to Buy 3-Fluoro-4-trifluoromethyl pyridine in China?
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    Frequently Asked Questions

    As a leading 3-Fluoro-4-trifluoromethyl pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-fluoro-4-trifluoromethylpyridine?
    3-4-trimethylpyridine is mainly used in a wide range of fields such as engineering, engineering, and materials.

    , this compound is often used in the synthesis of polymers. Due to its special properties, it can be used as a reaction to build a biologically active molecular skeleton. For example, in the synthesis of some anti-tumor compounds, 3-4-trimethylpyridine can be introduced into the molecule in a specific reverse step, which can improve the targeting and cytotoxicity of the tumor cells, and can inhibit the growth of tumors. In another example, in the development of antibacterial substances, it can be used as an important starting material to generate compounds with antibacterial activity to resist multi-bacterial infection.
    In the field, this compound also has a value. It can be used in the synthesis of new types of bacteria, bacteria and other products. Due to its unique characteristics, the synthesized product can be used to prevent and control specific crop pests or pathogens with high efficiency, and the impact of the environment is small, which meets the requirements of high efficiency, low toxicity and low retention for the next generation. For example, from a series of chemical modification, it can be made into a certain kind of regular crop damage, effectively protecting crops from damage and improving the quality of crops.
    In terms of materials, 3-4-trimethylpyridine can be used for the synthesis of high-performance polymer materials. In polymerization, it is functional and can make the synthesized polymer materials have special properties, such as good qualitative, mechanical or mechanical properties. This material can be used in high-end fields such as sub-devices and aerospace. For example, in the research of sub-sealing materials, polymeric materials containing this compound can effectively improve the resistance of sealing materials and ensure that sub-devices can operate under high-quality, high-quality and other harsh conditions.
    What are the synthesis methods of 3-fluoro-4-trifluoromethylpyridine?
    To prepare 3-hydrocarbon-4-trihydrocarbon methyl pyridine, there are three methods.
    First, the corresponding pyridine derivative is used as the starting material, and the hydrocarbon group is added by substitution reaction. Pyridine can be taken first, and under appropriate conditions, halogenated hydrocarbons are used as hydrocarboning reagents. Under the catalytic action of bases, the hydrocarbons of halogenated hydrocarbons are substituted for hydrogen atoms at specific positions on the pyridine ring to obtain pyridine intermediates containing the desired hydrocarbons. In a suitable reaction system, the intermediates are further modified to introduce trihydrocarbons at specific positions. This process requires attention to the control of reaction conditions. Temperature, reaction time and the proportion of reagents will all affect the yield and purity of the product. < Br >
    Second, the condensation reaction strategy is adopted. Compounds containing active carbonyl groups can be used with ammonia or amines, and condensation can be carried out under appropriate catalysts and reaction conditions. For example, the condensation of aldums, ketones and ammonia or amines with suitable structures forms the skeleton of the pyridine ring. At the same time, during the condensation process, the structure of the reactants is cleverly designed so that trihydrocarbon methyl and other hydrocarbons can be precisely connected to the target position during the formation of the pyridine ring or in subsequent reactions. This approach requires in-depth understanding of the structure and reactivity of the reactants, and careful planning of the reaction steps to achieve the desired effect.
    Third, the coupling reaction with the help of metal catalysis. First, pyridine derivatives containing halogen atoms or other couplable groups are prepared, and then the coupling reaction catalyzed by metal catalysts such as palladium and nickel is used to react with organometallic reagents containing hydrocarbyl groups or other suitable coupling reagents. In this way, hydrocarbyl and trihydrocarbon methyl can be efficiently and selectively introduced into the pyridine ring to construct the structure of 3-hydrocarbon-4-trihydrocarbyl methyl pyridine. The coupling reaction conditions of metal catalysis are usually relatively mild and highly selective, but the choice of catalyst and the purity of the reaction system are required. Otherwise, side reactions will easily occur and the quality of the product will be affected.
    What are the physical properties of 3-fluoro-4-trifluoromethylpyridine?
    3-Bifurcation-4-trifurcation methylpyridine is an organic compound, and its physical properties are as follows:
    Viewed, this substance is mostly in a liquid state at room temperature and pressure, and its color may be colorless to light yellow, clear and transparent, like a clear spring, with no visible impurities.
    Smell it, it has a special smell, or it is slightly irritating, or it has a slight aromatic rhyme. However, the smell is not pleasant, and it is very different from the common floral and fruity aroma. The smell is impressive.
    As for its boiling point, it is about a certain temperature range. This temperature varies slightly due to specific chemical structures and environmental factors. The existence of the boiling point makes the substance gradually change from liquid state to gaseous state when it reaches a specific temperature during the heating process, just like ice melts into water, and water rises into steam.
    Melting point is also one of its important physical properties. When the temperature drops to a certain value, the substance solidifies from liquid state to solid state, just like water freezes into ice when it is cold, and this temperature is the melting point.
    In terms of solubility, in organic solvents, such as ethanol, ether, etc., it shows good solubility and can be melted with it, just like salt dissolves in water, which is seamless; in water, its solubility is relatively limited, part is soluble, and part is suspended or stratified, showing different characteristics from water. < Br >
    The density is slightly different from that of water, or lighter than water, floating on the water surface; or heavier than water, sinking on the bottom of the water, this characteristic is also the key to identification.
    In addition, its refractive index has a specific value. When light passes through the substance, refraction will occur. The angle and degree of refraction depend on this refractive index. This is an important means of analyzing and identifying the substance.
    What are the precautions for storing and transporting 3-fluoro-4-trifluoromethylpyridine?
    3-Hydroxy-4-trihydroxymethylpyridine has many things to pay attention to when storing and transporting.
    The first thing to pay attention to is the storage environment. This substance should be stored in a cool, dry and well-ventilated place. Due to its chemical properties, if it is exposed to high temperature, humidity, or changes in properties, it will affect its quality. For example, high temperature can promote chemical reactions, humid environments or make it deliquescent, so it is necessary to ensure that the storage environment is suitable.
    Furthermore, pay attention to isolation from other substances when storing. 3-Hydroxy-4-trihydroxymethylpyridine may react with certain chemicals, such as strong oxidizing agents, strong acids and bases, etc. If it is mixed with it, it may cause serious consequences such as fire and explosion. It should be strictly classified during storage to avoid contact with each other.
    When transporting, the packaging must be sturdy and reliable. Appropriate packaging materials must be used to ensure that no leakage is caused by bumps and collisions during transportation. The packaging should be able to withstand certain external forces and have good sealing. If a special sealed container is used, it should be prevented from coming into contact with outside air and moisture.
    At the same time, the transportation process should follow relevant regulations and standards. Transportation personnel need to be familiar with the characteristics of this substance, and transportation vehicles should also be equipped with corresponding emergency treatment equipment. If there is an accident such as leakage during transportation, effective measures can be taken quickly to reduce the harm. For example, prepare the adsorption material so that it can be adsorbed in time to prevent its spread.
    What is the market outlook for 3-fluoro-4-trifluoromethylpyridine?
    "Tiangong Kaiwu" says: "Silk, hemp, furs, and browns in the world all have qualities, which make the unique colors of the face still exist. I don't believe it if I say that the creation of things is not laborious." The genus of husband pigments can also be studied in the future of the city.
    Today's view of 3-hydroxy- 4-trihydroxymethyl pyridine, which is an important raw material for chemical pigments. The world is bustling, all for profit; the world is bustling, all for profit. The use of chemical pigments involves a wide range of industries, such as printing and dyeing, and fabrics are bright in color and luster, and will not fade for a long time. This raw material is indispensable.
    The prosperity of the printing and dyeing industry is related to people's livelihood. Since ancient times, the people of China have attached great importance to the color of clothing. Today, the world's pursuit of clothing is not only to keep the body warm, but also to its beauty and fashion. Therefore, the art of printing and dyeing is increasingly refined, and the need for pigments is also growing. 3-Hydroxy-4-Trihydroxymethylpyridine, as a key raw material, its market prospects are like seedlings in spring. Although it does not increase, it grows day by day.
    In addition, the paint industry also depends on pigments. The decoration of houses and the decoration of utensils all need colorful paints. The preparation of 3-Hydroxy-4-Trihydroxymethylpyridine in paint pigments can increase the stability and durability of its color. Nowadays, the construction of urban and rural areas is changing with each passing day, high-rise buildings have sprung up like bamboo shoots after a rain, and the amount of paint has increased sharply, which has also ushered in a broad market for this raw material.
    However, the prospect of the city is not only bright and cloudless. With the advance of science and technology, the research of new pigments is emerging one after another. If you don't think about making progress, follow the old ways, or worry about being replaced by new things. Therefore, all businesses should be swimming against the current. If you don't advance, you will retreat. You should be attentive to the research, production and sales of raw materials in order to occupy a stable place in the market. In this way, the market prospect of 3-hydroxy- 4-trihydroxymethylpyridine is as bright as the sun, shining brightly.