3-Fluoro-4-nitropyridine 98+%

3-Fluoro-4-nitropyridine, with a purity of more than 98%, has a wide range of uses. In the field of organic synthesis, it is often a key raw material. The presence of fluorine atoms and nitro groups in its structure gives it unique reactivity.
In the field of pharmaceutical chemistry, it can be used as a starting material for the synthesis of many new drug molecules. The introduction of fluorine atoms can often change the physical and chemical properties of drug molecules, such as lipophilicity, metabolic stability, etc., which in turn affect the biological activity and pharmacokinetic properties of drugs. Nitro can be converted into amino groups and other functional groups through reactions such as reduction, laying the foundation for the subsequent construction of complex drug structures.
In materials science, it also has its uses. It can participate in the preparation of organic materials with special properties, such as optoelectronic materials. With its unique electronic structure, it may endow materials with specific optical and electrical properties, such as fluorescence properties, charge transport ability, etc., which can be applied to the research and development of organic Light Emitting Diodes, solar cells and other devices.
In addition, in the field of pesticide chemistry, it may also be used as an important intermediate for the synthesis of highly efficient and low-toxicity pesticides. By modifying and modifying its structure, it is expected to develop pesticide products with unique mechanisms of action and good insecticidal or bactericidal activities, which will contribute to the sustainable development of agriculture. In conclusion, 3-fluoro-4-nitropyridine has shown important application value in many fields due to its unique chemical structure, promoting the progress of related science and technology.

3-Fluoro-4-nitropyridine, with a content of more than 98%. Its physical properties are as follows:
This substance is mostly in solid form at room temperature, with a specific crystalline appearance. The crystal form is regular and orderly, reflecting the regularity of the internal molecular arrangement. The melting point is in a certain temperature range. By precise experimental determination, the melting point is of great significance to its phase transition in different environments.
Its density is also an important physical property, reflecting the mass of the substance in a unit volume and is related to the degree of intermolecular compactness. This property affects the position and distribution of the substance in the mixed system.
In terms of solubility, it exhibits a certain solubility in specific organic solvents such as ethanol and dichloromethane. In ethanol, some molecules interact with ethanol molecules by intermolecular forces, thus dissolving; but in water, its molecular structure is difficult to form an effective interaction with water molecules, so the solubility is poor.
The appearance color is often light yellow to yellow, which is due to the absorption and reflection of specific wavelengths of light by the molecular structure. This color feature can be used as a preliminary identification basis.
In addition, 3-fluoro-4-nitropyridine has a certain odor. Although it is not strong and pungent, it can still be detected. Its odor is caused by the evaporation of molecules into the air and the interaction with olfactory receptors.
Understanding these physical properties is crucial for their application in chemical synthesis, pharmaceutical research and development, and can help researchers design reaction conditions and choose separation and purification methods based on their properties.

3-Fluoro-4-nitropyridine, the content is more than 98%, and its chemical properties are quite stable. In this compound, the presence of fluorine atoms and nitro groups makes it have unique chemical activity and stability. Fluorine atoms, due to their high electronegativity, will affect the electron cloud distribution of the pyridine ring, resulting in a decrease in the electron cloud density on the pyridine ring, enhancing the activity of its electrophilic substitution reaction; however, this change in the electron cloud distribution also stabilizes the molecular structure to a certain extent.
Nitro, as a strong electron-absorbing group, also exerts an effect on the electron cloud distribution of the pyridine ring, further enhancing the activity of the pyridine ring for electrophilic substitution reaction, especially in the meta-position. However, under normal storage and general environmental conditions, 3-fluoro-4-nitropyridine can maintain a relatively stable state.
However, in case of specific chemical reagents or reaction conditions, such as strong reducing agents, high temperatures, strong acids or strong bases, its stability will be challenged. For example, under the action of strong reducing agents, nitro groups may be reduced to amino groups, thereby changing the chemical properties and structure of molecules; at high temperatures and in the presence of suitable reaction substrates, electrophilic substitution reactions may occur, and fluorine atoms or nitro groups may be replaced by other groups. However, in general, in conventional laboratory storage and general industrial operating environments, as long as the above extreme conditions are avoided, the chemical properties of the substance are relatively stable, and its original structure and properties can be maintained for a long time.

The preparation of 3-fluoro-4-nitropyridine (with a content of more than 98%) is a delicate and meticulous process. Its preparation often follows the path of chemical synthesis, which involves multiple rigorous steps and precise control.
Initially, pyridine is often used as the base material. Pyridine has a stable structure and specific reactivity, which lays the foundation in the initial stage of synthesis. To introduce fluorine atoms and nitro groups, careful selection of reagents and reaction conditions is required.
Introducing fluorine atoms often involves nucleophilic substitution. If a suitable fluorine-containing reagent is used, it will react with pyridine derivatives under the action of specific solvents and catalysts. The properties of solvents are related to the reaction rate and product purity. For example, polar aprotic solvents are often preferred because they can promote the activity of nucleophiles. The choice of catalysts is also critical, or metal salts, etc., which can effectively reduce the activation energy of the reaction and accelerate the process of fluorine atom substitution.
The introduction of nitro groups uses more nitrification reactions. The mixed acid system of nitric acid and sulfuric acid is used as a nitrifier. In this system, pyridine undergoes electrophilic substitution reaction under specific temperature and time conditions. Temperature control is extremely important. If the temperature is too high, it is easy to cause side reactions to occur and generate polynitro substitution products; if the temperature is too low, the reaction rate is delayed and the yield is affected. Therefore, it is often necessary to slowly add mixed acids at low temperature to maintain a mild and controllable reaction.
After fluorine atoms and nitro groups are successfully introduced, the product needs to be separated and purified. This process often involves extraction, distillation, recrystallization and other steps. Extraction can separate the organic phase and the aqueous phase to preliminarily enrich the product; distillation is based on the difference in the boiling point of the product and impurities to further purify; recrystallization can obtain high-purity crystal products. By selecting a suitable solvent, the product can be dissolved and crystallized in it to eliminate impurity interference. After this series of processes, 3-fluoro-4-nitropyridine with a content of more than 98% can be obtained.

What you are inquiring about is that 3-fluoro-4-nitropyridine, with a purity of more than 98%, is within the price range of the market. However, the price of this chemical often changes due to multiple reasons, making it difficult to determine directly.
First, the supply and demand situation has a lot to do with it. If the demand below is strong and the supply is small, the price will increase; conversely, if the supply is sufficient and the demand is small, the price will decrease.
Second, the difficulty of preparation is also the main reason. If its synthesis requires complex processes and special raw materials, the cost will be high, and the price will follow.
Third, the origin is different, and the price is also different. If you supply it from a nearby place, the freight will be saved, and the price may be low; if you come from a distant place, plus the cost of freight, the price may increase.
Fourth, the intensity of market competition can also be affected. Businesses compete, or make profits to seize the market, and the price fluctuates.
Based on past experience, the price of such chemicals per gram may range from tens to hundreds of yuan. However, this is only a rough estimate. The actual price should be consulted with chemical raw material suppliers, reagent sellers, etc., to determine the current accurate price range.