3-Fluoro-2-pyridinecarboxylic acid

3-2-pentene has the chemical properties of acrylic acid, but it has the same characteristics. It has the property of addition and inverse. It can be added from element, chemical, etc. In case of bromine water, the atom of bromine can be added to the end, so that the bromine water fades. This is not a way to sum up.
And because it contains carboxyl groups, it is acidic. It can be neutralized and reversed. For example, an oxidized solution is mixed, and the oxidized group of the carboxyl group is combined with water to form a carboxylic acid. It can also be esterified and reversed by alcohol. Under acid catalysis, the carboxyl group of the alcohol is hydrated to produce a fragrant ester compound.
And the mixture can generate polymerization and reverse reaction due to the presence of carboxylic groups. Under the appropriate composition, it will crack and form a polymer with each other, which is significant in the field of synthetic materials. Its incompatibility also makes it oxygenated and reversed, and can be oxidized, cracked, and the properties of carboxylic groups may also be reduced. In addition, 3-2-pentene acrylic acid has important uses in the fabrication of polymers.

The common channels of acetic acid include distillation, extraction, and crystallization.
The method of distillation covers the difference in boiling points between acetic acid and other substances. The boiling point of acetic acid is about 117.9 degrees Celsius. If the boiling points of various substances in the mixture are quite different, heat the mixture. If the boiling point is low, it will first turn into steam, which will be condensed into a liquid and separated. This method is often used to enrich acetic acid from dilute acetic acid solutions, and can also remove impurities with very different boiling points.
For extractors, choose an organic solvent that is insoluble with water and has good solubility to acetic acid. Such as ether, it is insoluble with water, and acetic acid has a high solubility in ether. The aqueous solution containing acetic acid is mixed and shaken with ether, left to stand for stratification, and the acetic acid is dissolved into the ether layer. Then the ether layer is separated, and then the ether and acetic acid are separated by distillation and other methods to obtain pure acetic acid.
The crystallization method is based on the characteristic that the melting point of acetic acid is 16.6 degrees Celsius. When the temperature drops below the melting point, acetic acid can crystallize and precipitate. If the impurities in the mixture are not easy to crystallize at low temperature, the temperature is controlled to crystallize acetic acid, and the filtration can obtain pure acetic acid crystals.
These are all common ways to obtain and purify acetic acid, and are widely used in chemical, pharmaceutical and other fields.

In the synthesis of 3-alkynyl-2-pentenoic acid, there are various paths. First, it can be started from a suitable halogenated olefin. The halogenated olefin is reacted with a metal reagent with an alkynyl group, such as lithium alkynyl or magnesium alkynyl, according to the mechanism of nucleophilic substitution. In a suitable solvent, such as anhydrous ethyl ether or tetrahydrofuran, at low temperature or room temperature, the halogenated atom of the halogenated olefin can be replaced by an alkynyl group to form an intermediate containing alkynyl and alkenyl groups. Then, by suitable carboxylation means, such as reacting with carbon dioxide under specific conditions, the intermediate can be converted into 3-alkynyl-2-pentenoic acid. < Br >
Second, it can be started from alcohols containing alkenyl and alkynyl groups. First, the alkynyl alcohol is oxidized, and a suitable oxidizing agent, such as Dice-Martin oxidizing agent or Jones reagent, is selected to oxidize the alcohol hydroxyl group to an aldehyde group or a carboxyl group. If oxidized to an aldehyde group, the aldehyde group can be further oxidized to a carboxyl group by mild oxidation, such as the use of weak oxidizing agents such as Torun reagent, etc., to obtain 3-alkynyl-2-pentenoic acid.
Furthermore, a modification of the malonate ester synthesis method can be used. In the reaction of malonate with halogenated hydrocarbons containing alkenyl and alkynyl groups, under alkaline conditions, the methylene hydrogen of malonate is deprived by alkali, forming carbon anion, and then nucleophilic substitution with halogenated hydrocarbons. After that, the target product 3-alkyne-2-pentenoic acid can be synthesized through hydrolysis, decarboxylation and other steps. During the whole synthesis process, attention should be paid to the precise control of reaction conditions, such as temperature, pH, and the equivalent of reagents, to ensure the efficient progress of the reaction and the high purity of the product.

What you are asking is about the price range of 3-hydroxy- 2-pentenoic acid in the market. However, in order to clarify its price, many reasons need to be considered in detail.
First, the quality of this product is closely related to its purity. If it is of high quality and purity, its price will be high; if it is of poor quality and miscellaneous, its price will be low.
Furthermore, the supply and demand of the market is also a major factor. If there are many applicants and there are few suppliers, the price will rise; if the supply exceeds the demand, the price may fall.
In addition, the place where this acid is produced and the way of transportation also have an impact on the price. If the place of origin is close to the city, and the cost of transportation is saved, the price may be low; if the place of origin is far away, and the freight is complicated, the price may be high.
In addition, the method and cost of making this acid are also related to its price. The law is good but the cost is low, and the price can be close to the people; the law is clumsy but the cost is high, and the price must be high.
As far as I know, in the current city, 3-hydroxy- 2-valentenoic acid, if the purity is ordinary, the price per catty may be between tens of dollars and hundreds of dollars; if the purity is high, it may reach hundreds of dollars per catty. However, this is only a rough number. The market conditions are impermanent, and the price changes at any time. It is difficult to determine Those who need to purchase should carefully observe the dynamics of the city and visit the merchants before they can obtain a more accurate price.

The storage of 3-2-2-acetic acid should be placed in a place where it is dry, dry, and well-connected. Acetic acid is toxic. If it is exposed to high temperature or tidal conditions, it is easy to disperse, and it may be generated due to tidal pressure, causing it to suffer.
It should be stored in a dense container, which can prevent it from being connected to the air. Acetic acid is prone to some components in the air, such as carbon dioxide, etc. The sealing device can block this reaction and ensure its stability.
And the source of ignition and oxidation. Acetic acid is flammable, and it is flammable or even explosive in case of fire; and the oxidation energy is strong, endangering safety.
For storage, the resistance should be limited to a certain temperature, usually 5 ° C to 35 ° C. Below this temperature, or cause it to solidify, and above this limit, the speed will be accelerated. The resistance is also controlled to a reasonable level. Generally, the phase resistance should not exceed 75% to avoid moisture.
During the storage process, it is necessary to regularly check the tightness of the container and the performance of acetic acid. If there is any leakage or damage, it will be treated immediately to ensure the safety of its products.