3-Fluoro-2-hydroxypyridine

3-2-Furanoacronaldehyde, its main uses are as follows:
First, in the field of food, this substance is often used as food flavoring. Because it can give food a special fragrance, it can add food flavor. For example, in baked goods, it can generate a special baking aroma, such as baking bags, cakes, etc., so that the finished product is fragrant and enhances people's food. It is also used in some flavored products to add rich flavors and enhance the taste of the whole product.
Second, in the chemical industry, 3-2-Furanoacronaldehyde can be used as a fragrance component and added to chemical products. It can improve the attractiveness and marketability of the chemical product, not only does it give the user better senses in the process of use, but also can improve the attractiveness and marketability of the chemical product when the natural or synthetic fragrance ingredients are in line with the relevant conditions.
Third, in the chemical industry, it is an important synthetic ingredient. Due to its special molecular properties, many bioactive compounds can be derived through chemical reactions. Some of the compounds synthesized from this raw material have demonstrated their biological activity in the chemical research, for example, they may have antibacterial, anti-inflammatory and other effects, and the new research provides an important material base. In addition, in some fine chemical synthesis, it is also often used to build specific chemical compounds and to produce chemical materials with special properties.

3-En-2-furanylacetone, its physical properties are as follows:
This substance is mostly colorless to light yellow liquid at room temperature, with a special and unique aroma, just like fruity and burnt blend, and the aroma is rich and long-lasting, and it is widely used in the field of fragrance preparation.
Its boiling point is about 115-117 ° C/1.6 kPa. This boiling point characteristic allows it to change from liquid to gaseous under specific pressure conditions. This property is crucial in chemical operations such as separation, purification and reaction condition control.
The melting point is around -21 ° C, indicating that when the temperature drops to this value, the substance solidifies from liquid to solid. The melting point is closely related to the intermolecular force, reflecting the characteristics of molecular arrangement and interaction.
The relative density is about 1.109 - 1.113 (20 ° C), which means that at 20 ° C, the density of the substance and the density of pure water at 4 ° C are within this range, so that it can be identified and separated in operations such as mixture separation through density differences.
The refractive index is about 1.491 - 1.495 (20 ° C). This is the ratio of the incident angle sine to the refractive angle sine when light propagates in the substance. The specific value of the refractive index is of great significance to the identification of the purity and concentration of the substance. Because the refractive index of the pure substance is constant under specific conditions, if impurities are mixed in, the refractive index will change.
3-phenyl-2-furanoacetone is slightly soluble in water, but it can be miscible with organic solvents such as ethanol and ether. The difference in solubility is due to its molecular structure. The force between the internal molecular groups and the organic solvent molecules is similar, so it can be miscible with each other, while the force with water molecules is weak, causing it to be slightly soluble in water. This solubility characteristic has far-reaching effects on material extraction, separation and reaction medium selection.

3-3-2-furanylacetone, which is a chemical compound. It has special chemical properties, let me describe it to you.
First of all, 3-2-furanylacetone is often liquid and has certain properties. Under normal conditions, it can be dispersed in the air. Its outer color or a transparent liquid of color to light color, which seems to have a faint light flow, like the morning dew on the tip. Its flavor is characteristic, with a fragrant fragrance, a slightly sweet fragrance, and the special interest given by furan. This flavor is often used in the field of fragrance, and can add its special flavor to various flavors.
And then its chemical activity, in the molecule, the acetone phase of furan. Furan has aromatic properties, but its aromaticity is weaker than that of benzene, because of its special distribution of sub-clouds, so that the carbon atom activity on furan is different. The acetone group, which contains carbonyl, and the carbonyl group, has a strong effect, so that the carbonyl carbon is partially positively charged and vulnerable to nuclear attack.

When encountering nuclei, such as alcohols, amines, etc., the carbonyl carbon of 3-2-furanylacetone can be added to the nucleus. Taking alcohols as an example, under the catalysis of acid or alcohol, the solitary ions on the oxygen atom of the alcohol attack the carbonyl carbon to form a semi-aldehyde or an aldehyde. If the amine is reversed, it can form a phase of the amine compound. This amine compound is often important in the synthesis, and it can be obtained in one step. Many compounds are derived.
In addition, due to the existence of furanoacetone, 3-2-furanoacetone can also be used as the opposite of the raw furan. For example, under certain conditions, it can be replaced on furanoacetone. Due to the high cloud density on furanoacetone, it has a certain attractiveness. However, this inversion needs to be controlled effectively. Due to the difference in the qualitative phase of furan, the inversion is easy to cause damage due to heat.
Of course, 3-2-furanylacetone has its own unique properties, and it has important uses in various fields such as synthesis and fragrance. It is an important compound that cannot be ignored in the study of chemical engineering.

There are many methods for the synthesis of 3-alkyne-2-furanylacronaldehyde. One is to use furan as the starting material and obtain it through multi-step reaction. In the first step, the nucleophilic substitution reaction between furan and halogenated hydrocarbons occurs under the action of strong bases, and the corresponding substituted furan is generated. In this step, attention should be paid to the control of the reaction conditions. The temperature and the amount of base have a great impact on the reaction yield.
Then, the obtained substituted furan and alkynyl reagent are coupled under the catalysis of transition metals. Commonly used transition metals such as palladium and copper, the coupling reaction conditions are more severe, and the choice of reaction solvent and ligand is also exquisite. Through precise regulation, furan derivatives containing alkynyl groups can be obtained.
Finally, the derivative is oxidized and converted into 3-alkynyl-2-furanylacronaldehyde. The oxidation step can be selected with a suitable oxidizing agent, such as manganese dioxide, etc. The reaction is carried out in a suitable solvent and temperature to obtain a higher yield.
Another synthesis method is to take a simple compound containing furan and alkynyl groups as the starting material and construct the target product through a condensation reaction. First, the aldehyde-containing furan derivative and the alkynyl compound undergo a condensation reaction under the action of an alkaline catalyst. In this process, the alkalinity and reaction time are all related to the reaction process. In the
reaction, the proportion of the reactants needs to be carefully adjusted to ensure that the reaction proceeds in the desired direction. Subsequent appropriate modification and purification steps can also successfully synthesize 3-alkyne-2-furanylacronaldehyde. This synthesis path is relatively simple, but each step also needs to be strictly controlled by the reaction conditions to improve the synthesis efficiency and product purity.

According to the state of the market, the price of 3-hydroxy- 2-furanylacetone often changes over time and varies with the situation. The price involved is related to all ends.
As far as raw materials are concerned, if they are widely sourced and easy to harvest, the price may be stable and cheap; if the source is sparse and difficult to harvest, the price will be high. Furthermore, the process is also heavy. The method is simple and easy, the production is large and the cost is small, and the price should be close to the people; if the method is difficult and the production is difficult and expensive, the price will be high.
And the market supply and demand determine its price. There are many who ask for it, but there are few who supply it, and the price is like a bird flying on the sky; oversupply, the stock is difficult to sell, and the price is like falling leaves. And competition in the same industry also has an impact. Businesses compete in the market, or reduce profits in order to sell, the price is down; there is no dispute in a single market, and the price is controlled, and the price is up.
Overall, the price is about tens to hundreds of dollars per catty. However, this is not a definite number, and it is difficult to determine because of the various market conditions. Only by observing the current situation, knowing the supply and demand, and knowing the craftsmanship can we know the approximate price.