3-ethyl 5-methyl (4S)-2-((2-aminoethoxy)methyl)-4-(2- chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

This is the English name of 3-ethyl-5-methyl- (4S) -2- ((2-aminoethoxy) methyl) -4- (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, which contains rich structural information. To know its chemical structure, listen to me in detail.
The pyridine ring is the core skeleton of this compound, which is like a stable cornerstone. On the structure of 1,4-dihydropyridine, there is an ethyl group at position 3, which is like extending an arm on the cornerstone and extending to the side. The 5-position is connected to the methyl group, which is like a small decoration.
The 4-position connection is particularly critical, not only chiral, the configuration is (S), but also connected to (2-chlorophenyl). The presence of chlorine atoms in this phenyl group gives the molecule a specific electronic effect and steric resistance.
The 2-position is connected by methylene (2-aminoethoxy). The aminoethoxy group is like a flexible chain, connected to the pyridine ring at one end, with an amino group and an ethoxy group at the other end. Amino groups can participate in many chemical reactions, and ethoxy groups also affect the solubility of molecules.
In addition, the 3 and 5 positions are respectively connected to carboxylic acid ester groups, which are like two wings and play an important role in the physical and chemical properties and biological activities of the molecule.
methyl, ethyl, chlorophenyl, aminoethoxy and carboxylic acid esters and other groups, through specific atomic connection sequence and spatial arrangement, jointly construct the unique chemical structure of this compound, and the parts cooperate with each other to determine the various properties and functions of the compound.

This is a chemical substance named 3-ethyl-5-methyl- (4S) -2 - ((2-aminoethoxy) methyl) -4 - (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. This substance has critical uses in the field of medicine and is often used as a treatment for cardiovascular diseases.
In terms of its pharmacological efficacy, such 1,4-dihydropyridine compounds are often calcium channel blockers. Calcium channels play an important role in the physiological activities of human cells, especially cardiomyocytes and vascular smooth muscle cells. By blocking calcium channels, this substance can regulate the influx of calcium ions, thus achieving the purpose of dilating blood vessels. After vasodilation, peripheral vascular resistance decreases, and blood pressure also decreases, so it is often used in the treatment of hypertension.
Furthermore, its effect on cardiomyocytes can reduce myocardial contractility and reduce myocardial oxygen consumption. This is of great significance in the treatment of angina pectoris, which can effectively relieve the pain symptoms caused by the imbalance of oxygen demand and oxygen supply in the myocardium. At the same time, it also affects the electrophysiological characteristics of the heart and can regulate arrhythmia to a certain extent.
In addition, in the field of scientific research, such compounds often become important research objects for drug research and development due to their unique chemical structure and biological activity. Scientists can modify its structure and explore the structure-activity relationship in order to develop new cardiovascular drugs with better efficacy and fewer side effects.

To prepare this substance, there are three methods. The first is obtained through a multi-step reaction. First, take the raw material containing chlorophenyl, and the compound with a specific structure in a suitable solvent, with the help of a catalyst, through condensation reaction, to obtain the key intermediate. This process requires strict control of temperature and reaction time, and the choice of solvent is very important. The choice of the other party can make the reaction proceed smoothly.
The second method uses substances with aminoethoxy groups and methyl groups as the starting materials, and is modified and cyclized. During modification, the ratio of reagents and the reaction conditions need to be carefully adjusted, otherwise the purity of the product will be affected. Cyclization one step requires strict reaction environment, pH and temperature are slightly deviated, and the product may not be required.
The third method starts from the precursor with the structure of pyridine, and introduces the substituents such as ethyl and chlorophenyl. Among them, the check point selectivity of the substitution reaction is extremely critical, and the specific catalyst and reaction conditions need to be selected to make the substituent fall precisely at the predetermined position, and the final product is 3 - ethyl + 5 - methyl (4S) -2 - ((2 - aminoethoxy) methyl) -4 - (2 - chlorophenyl) -6 - methyl - 1,4 - dihydropyridine - 3,5 - dicarboxylate. However, each method has its own difficulties, and it is necessary to choose carefully according to the actual conditions and needs.

There are 3 - ethyl + 5 - methyl + (4S) -2 - ((2 - aminoethoxy) methyl) -4 - (2 - chlorophenyl) -6 - methyl - 1,4 - dihydropyridine - 3,5 - dicarboxylate. The market prospect of this substance is related to many factors, which is a complex state.
Looking at its pharmaceutical field, if it has unique pharmacological activity, it may have potential utility in the treatment of cardiovascular diseases and other related treatments. Nowadays, there are many cardiovascular patients, and the demand is quite large. If this substance can be deeply researched and developed to become a targeted and effective drug, and the clinical trials are successful, and it is recognized by the medical supervision, it will be able to occupy a place in the market, and the prospects are quite promising.
However, there are also challenges. The road of pharmaceutical research and development is long and difficult, and huge investment is required. From basic research to clinical trials, to multi-phase clinical trials, there are many risks. If any link is frustrated, such as safety or effectiveness not meeting standards, it may lead to R & D interruption and investment will go to waste.
In the chemical industry, if it can be used as a special chemical raw material for the synthesis of other high value-added products, and the process is feasible and the cost is controllable, it may be able to open up a market. However, the chemical market is fiercely competitive, and factors such as congeneric product competition, stability of raw material supply and price fluctuations need to be considered. If the supply of raw materials is limited or the price fluctuates greatly, it will affect the production cost and market competitiveness.
In summary, 3-ethyl + 5-methyl + (4S) -2 - ((2 - aminoethoxy) methyl) -4 - (2 - chlorophenyl) -6 - methyl - 1,4 - dihydropyridine - 3,5 - dicarboxylate The market outlook is full of opportunities, but it is also full of thorns. It is necessary to weigh and evaluate all aspects and make prudent decisions. Only then can we hope to seize opportunities, avoid risks and seek development in the market.

This is 3-ethyl-5-methyl- (4S) -2 - ((2-aminoethoxy) methyl) -4 - (2-chlorophenyl) -6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. Quality Standards are critical to the quality and use of this compound.
According to "Tiangong Kaiwu", everything has its own rules, and this compound is no exception. Its purity is an important Quality Standard, and high purity can ensure its stable performance. It can be well used in many fields such as medicine and chemical industry. If the purity is insufficient, impurities or cause adverse reactions, or affect the reaction process.
Melting point is also a key criterion. Accurate melting point can prove the regularity of its structure and the excellence of its purity. Different purity or crystal form, melting point may be different, so the determination of melting point can be an important basis for judging its quality.
In addition, the inspection of relevant substances is indispensable. It is necessary to check whether this substance contains relevant substances in detail, because it may affect the quality and safety of the product. Through high performance liquid chromatography and other methods, the content of relevant substances can be accurately determined to ensure that it meets the specified range.
Furthermore, drying weight loss is also a consideration point. If there is too much moisture, it may cause deliquescence and deterioration of the product, affecting its stability and quality, so the proportion of dry weight loss needs to be strictly controlled.
In summary, the Quality Standards, purity, melting point, related material inspection, dry weight loss, etc. of this compound need to be strictly controlled to meet the needs of various applications in order to obtain high-quality products.