3-Ethyl-5-methyl-4-(2-Chlorophenyl)-2-(2-phthalimidoethoxl)-methyl-6-methyl-1,4-dihydropyridine-3,5-Dicarboxylate

This is the name of the chemical substance. To clarify its chemical structure, it is necessary to analyze the information contained in its name in detail. "3-Ethyl-5-methyl-4 - (2-chlorophenyl) -2 - (2-phthalimide ethoxy) -methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate".
The main body is the structure of "1,4-dihydropyridine", which is the core framework. It has an ethyl group at 3 positions, a methyl group at 5 positions, and a 2-chlorophenyl group at 4 positions. This chlorine atom is located at a specific position in the benzene ring.
Look at the 2 positions again, with "2-phthalimide ethoxy", which contains the phthalimide structure, which is connected to the main body by ethoxy group. At the same time, the 2 positions have methyl groups. The 6 positions are also connected with methyl groups.
And the 3 and 5 positions are respectively related to dicarboxylic acid ester groups. Combining the above parts, the chemical structure of the substance can be roughly outlined, which is like building a delicate chemical structure. Each part is connected to each other according to the rules indicated by the name, forming a unique chemical form. Therefore, the chemical structure of this substance is clarified according to its name.

3 - Ethyl - 5 - methyl - 4 - (2 - chlorophenyl) - 2 - (2 - phthalimide ethoxy) - methyl - 6 - methyl - 1,4 - dihydropyridine - 3,5 - dicarboxylate, this is an organic compound. Its use is quite extensive, in the field of medicine, or has important medicinal value. Or it can act as a key drug intermediate, which can be converted into an effective drug for the treatment of diseases through specific chemical reactions. Or show significant activity in the treatment of specific diseases, such as in the development of cardiovascular disease drugs, its special chemical structure may interact with relevant targets in the body, regulate physiological functions, and achieve therapeutic purposes.
In the field of materials science, the compound may have unique physicochemical properties. Or due to the special groups in the structure, it is endowed with certain optical and electrical properties, which can be used to prepare new functional materials. For example, in photoelectric device materials, it may improve the photoelectric conversion efficiency of materials and other properties, providing the possibility for the development of high-performance photoelectric devices.
In the field of organic synthetic chemistry, it can be used as an important synthetic building block. With its complex and unique structure, organic synthesis chemists can build more complex and diverse organic molecular structures through various organic reactions, thus contributing to the development of organic synthesis chemistry and expanding the synthesis paths and methods of new organic compounds.

To obtain 3 - ethyl - 5 - methyl - 4 - (2 - chlorophenyl) - 2 - (2 - phthalimide ethoxy) - methyl - 6 - methyl - 1,4 - dihydropyridine - 3,5 - dicarboxylate synthesis method, can follow the steps below.
First, take an appropriate amount of 2-chlorobenzaldehyde, ethyl acetoacetate, 2 - (2-phthalimide ethoxy) -methyl-3-ethyl-5-methyl-4-methylpyridine-3,5-dicarboxylate and place it in a clean reactor. The kettle must be an inert gas environment, with nitrogen or argon gas draining the air, so as to avoid the risk of oxidation of raw materials and products.
Next, add an appropriate amount of catalyst, which can be selected from an organic base such as piperidine. The organic base can promote the reaction, change the distribution of electron clouds between the reactants, and reduce the activation energy of the reaction.
Then, heat the reaction system. Heat to a suitable temperature, about 100-120 ° C, maintain this temperature and stir. When the stirring rate is moderate, the reactants are fully contacted, and the reaction proceeds uniformly. After the reaction has passed for several days, the reaction liquid can be taken regularly and observed by thin layer chromatography or liquid chromatography. The reaction can be stopped until the raw material point disappears or the expected conversion rate is reached.
After the reaction is completed, the reaction liquid is cooled to room temperature. Then extract with a suitable organic solvent, such as a mixed system of ethyl acetate and water. After multiple extractions, the product can be moved from the reaction system to the organic phase. Then dry the organic phase with anhydrous sodium sulfate to remove the moisture. After
, the dried organic phase is distilled under reduced pressure to remove the organic solvent and obtain a crude product. The crude product was purified by column chromatography, silica gel was selected as the stationary phase, and the mixed liquid of petroleum ether and ethyl acetate was used as the mobile phase. According to the difference in the partition coefficients of the product and impurities in the stationary phase and the mobile phase, it was separated to obtain a pure 3-ethyl-5-methyl-4 - (2-chlorophenyl) -2 - (2-phthalimide ethoxy) -methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.

This compound, 3-ethyl-5-methyl-4- (2-chlorophenyl) -2- (2-phthalimide ethoxy) -methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, has specific physicochemical properties. Its appearance is often crystalline powder with a nearly white to yellowish color, which is caused by the atomic arrangement and electron transition characteristics in the molecular structure. From the melting point point, it is about 180-190 ° C. Due to the interaction of intermolecular forces, hydrogen bonds and van der Waals forces, the lattice disintegrates when these forces are overcome at a specific temperature.
In terms of solubility, it shows good solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide, and is similar to organic solvents because the molecules contain polar and non-polar parts. However, the solubility in water is poor, because the proportion of hydrophobic groups is large, it is difficult to form effective interactions between water molecules and compound molecules.
In terms of stability, it is quite stable under normal storage conditions. In case of strong oxidizing agents, strong acids and bases, the structure may change. In case of strong acid, the dihydropyridine ring may be protonated, triggering a rearrangement of the ring structure; in case of strong base, ester group or hydrolysis, the molecular structure changes. Because acid and base can affect the distribution of molecular electron clouds and the stability of chemical bonds.
Spectral properties are also characterized. In the infrared spectrum, the strong absorption peak at 1700-1750 cm ¬ belongs to the stretch vibration of ester carbonyl, and the peak at 1600-1650 cm ¬ originates from the vibration of the benzene ring skeleton. Due to the specific vibration frequencies of different chemical bonds, it absorbs light of a specific frequency when irradiated by infrared light. In hydrogen NMR spectroscopy, hydrogen atoms in different chemical environments peak at the corresponding chemical shifts, providing key information for structure identification. The resonance frequencies are different due to the different electron cloud densities around hydrogen atoms.

Today there is a substance called 3-ethyl-5-methyl-4- (2-chlorophenyl) -2 - (2-phthalimide ethoxy) -methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. This substance is of great concern to many people in the market.
In the past, such compounds may still be new and have not been widely spread in the city. However, today is different from the past. The art of chemistry is advancing day by day, and there are many people who are seeking it. Such heterocyclic compounds with special structures are gradually gaining attention in the world because of their potential wonders in various fields such as medicine and materials.
In the field of medicine, with its unique structure, it may become the basis for the creation of new drugs. Drug developers hope that it can exhibit unique biological activities, such as antibacterial, anti-inflammatory, anti-tumor and other effects. Therefore, in recent years, the demand for such compounds in the market has been growing slightly.
As for materials, because of their structural properties, they may participate in the construction of materials with special properties, such as optoelectronic materials. Although the application is not widely used at present, some researchers have ventured into it to explore its possibilities.
From this point of view, 3-ethyl-5-methyl-4 - (2-chlorophenyl) -2 - (2-phthalimide ethoxy) -methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate has not yet reached prosperity in the city, but it has emerged. With the deepening of research, there may be more considerable development in the future.