3 Chloro 4 Pyridinecarbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

3-Chloro-4-pyridinecarbaldehyde

    Specifications

    HS Code

    552750

    Chemical Formula C6H4ClNO
    Molar Mass 141.55 g/mol
    Appearance Solid
    Color Light yellow to off - white
    Melting Point 44 - 48 °C
    Boiling Point 244 - 246 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point Approx. 101.4 °C

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    General Information
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    Frequently Asked Questions

    As a leading 3-Chloro-4-pyridinecarbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 3-Chloro-4-pyridinecarbaldehyde?
    3-Chloro-4-pyridyl formaldehyde, an organic compound, is characterized by its chemical properties. It has two important functional groups of aldehyde and chlorine atoms, which give the compound unique chemical activity.
    The aldehyde group is active and can participate in many reactions. For example, oxidation reactions, under the action of suitable oxidants, the aldehyde group can be oxidized to carboxyl groups to generate 3-chloro-4-pyridyl carboxylic acid. A reduction reaction can occur again, and when treated with a suitable reducing agent, the aldehyde group can be converted into a hydroxyl group to obtain 3-chloro-4- (hydroxymethyl) pyridine. The aldehyde group also often participates in nucleophilic addition reactions, like with alcohols under acid catalysis conditions, acetals can be formed.
    And chlorine atoms also have their own characteristics. Due to the large electronegativity of chlorine atoms, the carbon-chlorine bonds connected to them have a certain polarity. In nucleophilic substitution reactions, chlorine atoms can be replaced by a variety of nucleophilic reagents. For example, when reacted with sodium alcohol, chlorine atoms can be replaced by alkoxy groups to generate corresponding ether compounds; when reacted with amines, nitrogen-containing substitution products can be obtained. 3-Chloro-4-pyridyl-formaldehyde is active due to the presence of aldehyde and chlorine atoms. It is often used as a key intermediate in the field of organic synthesis to prepare organic compounds with diverse structures and functions.
    What are the main uses of 3-Chloro-4-pyridinecarbaldehyde?
    3-Chloro-4-pyridyl formaldehyde, this substance has a wide range of uses. In the field of pharmaceutical synthesis, it is often a key intermediate. Due to its unique structure, it can undergo a variety of chemical reactions to derive many biologically active compounds, such as the preparation of some antibacterial and antiviral drugs. It may be a starting material. After delicate reaction steps, it can eventually become an effective agent to treat diseases.
    In the field of materials science, it is also used for extraordinary purposes. It can participate in the preparation of specific functional materials, such as luminescent materials. After reasonable compatibility and reaction with other compounds, it can give the material unique optical properties, or it can be used for optical display, sensing, etc., to sense specific substances or environmental changes with its characteristics, and exert its detection ability.
    Furthermore, in the field of organic synthetic chemistry, it is an important cornerstone. Organic chemists use it as a starting point to use various organic reactions, such as nucleophilic addition, condensation, etc., to build complex organic molecular structures, expand the variety of organic compounds, and promote organic synthetic chemistry. It lays the foundation for the creation and performance optimization of new substances, which is of great significance to chemical research and industrial production.
    What are 3-Chloro-4-pyridinecarbaldehyde synthesis methods?
    There are various ways to synthesize 3-chloro-4-pyridine formaldehyde. First, it can be started from a pyridine compound. First, take a suitable pyridine derivative, use a specific halogenating agent, such as a chlorine-containing halogenating agent, and under suitable reaction conditions, halogenate the pyridine ring at a specific position, introducing chlorine atoms. This reaction requires precise temperature control and solvent selection to ensure that the chlorine atoms just fall at the target check point. Next, through a specific aldehyde-based step, another key functional group, aldehyde, is introduced to obtain 3-chloro-4-pyridine formaldehyde.
    Second, or start from compounds with similar structures. For example, for some substances containing pyridine rings and convertible groups, the convertible groups are first converted into aldehyde groups through a series of reactions, and at the same time, the pyridine rings are halogenated as appropriate, and chlorine atoms are added. In this process, each step of the reaction conditions needs to be carefully considered, such as reaction temperature, pH, catalyst selection and dosage, etc., which all affect the success or failure of the reaction and the purity of the product.
    Furthermore, classic strategies of organic synthesis can be borrowed, such as reverse synthesis analysis ideas. The target product 3-chloro-4-pyridyl-formaldehyde is inversely deduced, disassembled into several simple precursors, and then according to the organic reaction mechanism, each step of synthesis route is designed to realize the construction from simple precursor to target product one by one. This approach requires a good grasp of various organic reactions in order to plan ingeniously and obtain an ideal synthesis scheme.
    3-Chloro-4-pyridinecarbaldehyde What are the precautions during storage and transportation?
    3-Chloro-4-pyridyl formaldehyde is an organic compound. When storing and transporting, many things need to be paid attention to.
    When storing, the first choice of environment. It should be placed in a cool and ventilated place, because the substance is quite sensitive to temperature and air. High temperature can easily cause it to chemically react and deteriorate and damage; poor air circulation will make the local concentration too high and increase the risk. Be sure to keep away from fires and heat sources. Open flames and hot topics may cause danger, or cause combustion or even explosion.
    The storage place should be kept dry, because it has a certain water absorption. After being damp, it may affect the quality and even cause reactions such as hydrolysis. At the same time, it needs to be stored separately from oxidizing agents, acids, alkalis, etc. These substances may react violently with 3-chloro-4-pyridyl formaldehyde, causing danger.
    Furthermore, storage containers are also crucial. A well-sealed container is required to prevent leakage and volatilization, and the container material should be compatible with the substance to avoid interaction.
    During transportation, the packaging must be tight to ensure that the substance does not leak during bumps and vibrations. Transportation vehicles should be equipped with corresponding fire-fighting equipment to prevent accidents and respond in time. During transportation, keep away from fire and heat sources, and drive according to the specified route. Do not stop in densely populated areas and places with special requirements.
    In addition, whether it is storage or transportation, the relevant operators should have professional knowledge, be familiar with the characteristics of the substance, and know the emergency treatment methods, so as to ensure the safety of 3-chloro-4-pyridyl formaldehyde during storage and transportation and avoid accidents.
    What is the market price range for 3-Chloro-4-pyridinecarbaldehyde?
    I don't know the market price range of 3-chloro-4-pyridine formaldehyde. However, if you want to know its price, you can follow a number of paths. First, check in detail on the chemical raw material trading platform, which often collects the quotations of suppliers, and you can know the approximate price under different quality and quantity. Second, communicate directly with chemical product suppliers to inquire about their prices. Suppliers vary their prices due to their own costs and market supply and demand. If you inquire a few more, you can get a more accurate price range. Third, look at industry reports and information, which may involve the market price trend and current market conditions of the product. However, the market price is fluid and often changes due to changes in raw materials, policies, and demand. Therefore, if you want to obtain real-time and accurate prices, you must follow the above paths to explore.