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What are the main uses of 3-chloro-2-pyridinecarboxylic acid?
The main user of 3-bromo-2-pentenyl butyric acid, which is important in various fields.
In the field of organic synthesis, this is a key intermediate. Because of its special structure, it contains bromine atoms and carbon-carbon double bonds, both of which are highly reactive functional groups. Bromine atoms can interact with many nucleophiles, such as alcohols and amines, through nucleophilic substitution reactions, thereby introducing different functional groups and expanding the structural complexity of molecules. Carbon-carbon double bonds can be added to react, such as with hydrogen halide, water, etc., to build a variety of carbon skeletons, helping to synthesize various complex organic compounds, and making great contributions to drug synthesis and total synthesis of natural products.
In materials science, 3-bromo-2-pentenyl butyric acid also has a place. It can be introduced into the structure of polymer materials through its reactivity. For example, through the polymerization of double bonds, it becomes the structural unit of polymers, endowing materials with special properties, such as improving the mechanical properties and thermal stability of materials, or endowing them with special optical and electrical properties, etc., providing an important raw material basis for the research and development of new functional materials.
In the field of pharmaceutical research and development, the special structure of this compound may endow it with a certain biological activity. Researchers can modify and modify it based on its structure to explore derivatives with potential pharmacological activity, providing the possibility for the creation of new drugs. Or it can be used as a lead compound. After optimizing the structure, its affinity and selectivity to specific targets can be improved, and then innovative drugs with high efficiency and low toxicity can be developed, which will contribute to the cause of human health.
All these things, 3-bromo-2-pentenyl butyric acid, with its unique structure and reactivity, has shown important uses and broad application prospects in many fields such as organic synthesis, materials science, and pharmaceutical research and development.
What are the physical properties of 3-chloro-2-pyridinecarboxylic acid?
3-Bromo-2-pentenyl acrylic acid is an organic compound. Its physical properties are quite unique, as detailed below:
- ** Properties **: Under normal circumstances, this substance is mostly a colorless to light yellow liquid with a clear and transparent texture. This characteristic is similar to many similar organic compounds, all of which are in liquid form, due to its molecular structure and intermolecular forces.
- ** Odor **: Emissions a weak and special odor. The odor is not pungent or intolerable, but unique. The formation of this odor is closely related to the presence of bromine atoms, carbon-carbon double bonds, carboxyl groups and other functional groups in the molecule. The interaction of each functional group causes it to have unique odor properties. < Br > - ** Boiling point **: The boiling point is in a specific temperature range. Due to the presence of bromine atoms in the molecule, the atomic weight is large, and the influence of carbon-carbon double bonds and carboxyl groups increases the intermolecular force, so the boiling point is relatively high, and a specific temperature is required to transform from liquid to gaseous.
- ** Melting point **: The melting point is also in a specific low temperature range. The regularity of the molecular structure and the interaction of functional groups determine the temperature at which the solid-liquid transition. When the temperature drops below the melting point, the thermal motion of the molecules slows down, and they are arranged in a more orderly manner, so they solidify from liquid to solid.
- ** Solubility **: Shows good solubility in organic solvents such as ethanol and ether. This is because its molecules have a certain polarity, and can form interaction forces such as van der Waals forces and hydrogen bonds with organic solvent molecules, which makes it easily soluble in such organic solvents. However, the solubility in water is relatively poor. Due to the strong polarity of water molecules, the matching with the intermolecular forces of the compound is not good, making it difficult to dissolve in water.
- ** Density **: The density is greater than that of water. This is because the atomic weight of bromine atoms in the molecule is larger, resulting in an increase in the weight of the whole molecule. At the same volume, the mass is larger, so the density is higher than that of water. When mixed with water, it will sink to the bottom of the water.
What are the chemical properties of 3-chloro-2-pyridinecarboxylic acid?
The acetic acid of 3-bromo-2-pentene has the following chemical properties:
First, it has the commonality of olefins. Due to the carbon-containing carbon double bond, an addition reaction can occur. In case of bromine water, the π bond in the double bond is broken, and bromine atoms are added to the carbon atoms at both ends of the double bond to form a dibromine substitute. This is an electrophilic addition, and the color of bromine water fades, which can be used to identify olefins. Under the condition of catalyst and heating, it can hydrogenate with hydrogen to generate pentane, which is a reduction reaction and can be used to prepare alkanes. In case of hydrogen chloride gas, it can also be added. According to the Markov rule, hydrogen is added to the double-bonded carbon containing more hydrogen, and chlorine is added to the carbon containing less hydrogen to obtain the corresponding halogenated hydrocarbon.
Second, because the carbon atom connected to the bromine atom is separated by a carbon atom from the double bond, the bromine atom has a certain activity. In alkaline aqueous solutions, the bromine atom can be replaced by a hydroxyl group, and a nucleophilic substitution reaction occurs to generate 3-hydroxy-2-pentene. In this reaction, the hydroxide ion attacks the carbon atom connected to the bromine as a nucleophilic agent, and the bromine ion leaves. In basic alcohol solutions, elimination reactions are prone to occur. Bromine atoms are removed from hydrogen atoms on adjacent carbon atoms to form conjugated diolefins, which increase the stability of the molecule.
Third, due to the ester group in the molecule, there will be ester properties. Hydrolysis can occur under acid or base catalysis. In acidic hydrolysis, 3-bromo-2-pentenolyl alcohol and acetic acid are formed, and this reaction is reversible; in basic hydrolysis, 3-bromo-2-pentenolyl alcohol and acetate are formed, and the hydrolysis is more complete. This is a common chemical transformation of esters, which can be used to prepare corresponding alcohols and acids or their salts.
What is the production method of 3-chloro-2-pyridinecarboxylic acid?
The method of making 3-cyanogen-2-pentenyl acetic acid can be followed in ancient times.
To make this product, first take an appropriate amount of pentene and place it in a clean kettle. The pentene, the genus of the alkenes, is active. The kettle should be made of copper and iron, which is strong and can conduct heat. It is to slowly inject cyanide into the kettle. The cyanide agent needs to be carefully selected to ensure its purity. When the two meet, there is an additive reaction. Cyanogen root is active and attached to the double bond of the pentene. This process needs to be carefully controlled and heated slowly with charcoal fire, so that the temperature in the kettle is maintained in a moderate environment, not too high, so as to avoid side reactions. It should not be too low, causing the reaction to be slow.
After the cyanidation reaction is completed, add appropriate acetic anhydride. Acetic anhydride has the ability to acylate. After adding, it will change into acylation, so that the molecular structure is added with acetic acid groups, and the prototype of 3-cyano-2-pentenyl acetic acid is formed. This step also needs to pay attention to the length and conditions of the reaction, supplemented by a moderate acid-base environment, or a little catalyst can be added, so that the reaction speed and yield can be increased.
The reaction is final, and the product is mixed in various substances. It is purified by distillation, and 3-cyano-2-pentenyl acetic acid is separated from other substances by the difference in boiling points of different substances. When distilling, observe the fraction and collect the appropriate fraction in the middle, which is the crude product. Compound with the technique of recrystallization, select a suitable solvent, dissolve the product, then slowly cool down, and allow it to crystallize and precipitate, resulting in pure 3-cyanogen-2-pentenylacetic acid.
Although the ancients did not have the accurate equipment of today, they were able to explore such methods of preparation with experience and wisdom, laying the foundation for the future chemical industry, which can be praised.
What is the price range of 3-chloro-2-pyridinecarboxylic acid in the market?
I think what you are asking is about the price range of 3-bromo-2-pentenyl butyric acid in the market. However, this is not something I can immediately understand. The price of the market is often changed for many reasons.
Its source is also, and the amount of production will cause the price to vary. If there are many producers, the supply exceeds the demand, and the price may decline; if the production is thin, the supply is less than the demand, and the price will tend to rise.
Furthermore, the quality is also related to the price. If the quality is high, pure and with few impurities, the price should be high; if the quality is poor, there are many impurities, and the price must be low.
Also, the amount purchased also affects the price. If the purchase quantity is large, the seller may give a discount, and the price can be reduced; if the purchase quantity is small, there is no such discount, and the price is as usual.
And time and place, and the price is also involved. At different times, the price may change due to changes in supply and demand; in different places, the price varies according to the regulations of transportation fees and taxes.
Therefore, in order to know the exact price of 3-bromo-2-pentenylbutyric acid in the city, when visiting various merchants, consulting the city, or looking at the records of relevant transactions, you can get a more accurate price range. It is not up to me to decide.