3-Bromopyridine-5-Carboxaldehyde

3-Bromopyridine-5-formaldehyde, this is an organic compound. Its physical properties are unique, whether it is a colorless to light yellow liquid, or a solid, depending on the ambient temperature and purity. Under normal temperature and pressure, it is mostly liquid, with a certain volatility, causing its special smell to be smelled in the air.
Looking at its melting point, the melting point is about [X] ° C, and the boiling point is about [X] ° C. This melting boiling point characteristic is derived from the intermolecular force. In the molecule, the interaction of bromine atoms, aldehyde groups and pyridine rings makes the intermolecular attractive force reach a certain degree, and the melting boiling point is in the corresponding range.
In terms of solubility, 3-bromopyridine-5-formaldehyde is slightly soluble in water. Because its molecules have a certain polarity, but the pyridine ring has strong hydrophobicity with bromine atoms, it is difficult to dissolve in water with strong polarity. However, it is soluble in common organic solvents, such as dichloromethane, chloroform, ethanol, ether, etc. In organic solvents, molecules and solvent molecules can mix with each other by van der Waals force, hydrogen bonding, etc., showing good solubility.
On the density, its density is slightly higher than that of water, about [X] g/cm ³. This property makes 3-bromopyridine-5-formaldehyde sink to the bottom of the water if it is not miscible with water.
In addition, 3-bromopyridine-5-formaldehyde is sensitive to light and air. Light or long-term exposure to air can easily cause oxidation or other chemical reactions and cause it to deteriorate. Therefore, when storing, it should be placed in a cool, dry and dark place, and well sealed to ensure its chemical purity and physical stability.

3-Bromopyridine-5-formaldehyde, this substance has unique chemical properties. Its aldehyde group is active and easy to react, and can be added to nucleophiles with nucleophiles. Taking ammonia derivatives as an example, they can quickly react to form nitrogen-containing compounds such as oxime and hydrazone. They are often used as intermediates in organic synthesis to help build complex nitrogen-containing structures.
Its bromine atoms also have high reactivity and can participate in a variety of classical reactions. Under metal catalysis, such as palladium-catalyzed coupling reaction, they can be linked to carbon-containing nucleophiles to form new carbon-carbon bonds, providing a way to construct the carbon skeleton of pyridine derivatives, which are widely used in pharmaceutical chemistry and materials science.
Furthermore, the properties of the pyridine ring affect its overall chemical behavior. The pyridine ring has certain alkalinity, which can form salts with acids, change its own physical and chemical properties, and affect the solubility and reactivity in different solvents. In some reactions, the pyridine ring can also be used as an electron transfer medium to participate in the redox process.
In addition, the chemical properties of 3-bromopyridine-5-formaldehyde make it a variety of choices in the design of organic synthesis strategies. It can be reacted with aldehyde groups first and then treated with bromine atoms; it is also reversible, and can be flexibly adjusted according to the structure and needs of the target product, providing a powerful tool for the synthesis of organic compounds with specific structures and functions.

The common synthesis methods of 3-bromopyridine-5-formaldehyde cover the following numbers.
First, the method of using pyridine as the starting material. First, the pyridine is functionalized at a specific position, and the bromine atom is introduced at the third position of the pyridine ring through a halogenation reaction. This halogenation step requires a suitable halogenation reagent and reaction conditions, such as a specific brominating agent, reacted in a suitable temperature and solvent to ensure that the bromine atom falls precisely at the third position. Subsequently, the aldehyde group is introduced at the fifth position of the pyridine ring through an aldehyde reaction. This aldehyde-based process or the corresponding aldehyde-based reagent can be used to effectively introduce the 5-position aldehyde group in the presence of a catalyst by carefully adjusting the reaction parameters, such as temperature, pH, etc., so as to obtain the target product 3-bromopyridine-5-formaldehyde.
Second, the derivative containing the pyridine structure is used as the starting material. If the starting derivative already has some of the required functional groups, the target can be synthesized by the functional group conversion reaction. If the starting material contains groups that can be converted into bromine atoms and groups that can be converted into aldehyde groups, these groups can be converted sequentially or simultaneously through selective conversion reactions. For example, with a pyridine derivative containing a suitable substituent group, a specific group is first converted into a bromine atom through suitable reagents and conditions, and then another group is converted into an aldehyde group through another series of reactions. This process requires strict control of the selectivity and conditions of each step of the reaction to prevent side reactions from occurring, resulting in impure products or low yields.
Third, there are also synthetic pathways catalyzed by transition metals. Transition metal catalysts often play a key role in this process, promoting the introduction of bromine atoms and aldehyde groups in the pyridine ring or the conversion of functional groups. For example, transition metal catalysts such as palladium are used with specific ligands to catalyze halogenation and aldehyde reactions. The synthesis of 3-bromopyridine-5-formaldehyde can be efficiently achieved by optimizing factors such as catalyst, ligand, ratio of reaction substrate, and reaction environment (such as solvent, type and dosage of base). Due to the high activity and selectivity of transition metal catalysts, this path often achieves ideal reaction results, but it is necessary to pay attention to catalyst cost and recovery.

3-Bromopyridine-5-formaldehyde is used in various fields. In the field of medicinal chemistry, it is a key intermediate and is often used to prepare antibacterial and anti-inflammatory drugs. Its structure is unique, and it can introduce various functional groups to form bioactive compounds.
In the field of materials science, it also shows unique functions. Or it can participate in the preparation of organic materials with special properties, such as those with photoelectric activity, used in organic Light Emitting Diode (OLED), solar cells, etc., because its structure can help adjust the electronic properties of materials and optimize device performance.
In organic synthetic chemistry, this substance is an important building block. Chemists use the reactivity of aldehyde groups and bromine atoms to perform various organic reactions, such as nucleophilic addition, substitution, etc., to construct complex organic molecular structures, paving the way for the synthesis of novel organic compounds.
In addition, in the field of pesticide chemistry, it may be used as a raw material for the synthesis of high-efficiency and low-toxicity pesticides. After rational molecular design and reaction transformation, pesticide products with specific biological activities and good control effects against pests and pathogens can be created.

What I'm asking you is about the market price of 3-bromopyridine-5-formaldehyde. However, the market price of this compound is difficult to sum up. The price of this compound is influenced by many factors, which are like changes in the wind and clouds, and it is intricate.
First, the price fluctuation of raw materials has a great impact on it. If the raw materials required for the synthesis of this compound fluctuate due to production increases or decreases, changes in the situation of origin or other reasons, the cost of 3-bromopyridine-5-formaldehyde will also change, which will eventually affect its market price.
Second, the difficulty and cost of the preparation process are also key. If a process is complicated, requires high-end equipment, rare reagents, or consumes a lot of energy, resulting in high production costs, its price will not be low. On the contrary, if there is a simple and efficient method, the cost will be reduced, and the price may be close to the people.
Third, the market supply and demand relationship, such as the two ends of the scale, checks and balances the price. If the market demand for this product is strong, but the supply is limited, the merchant will raise the price in order to make a big profit; if the supply exceeds the demand, in order to get rid of it, the price will fall.
Fourth, the different manufacturers also make the price different. Large factories may be able to sell at a lower price due to scale effects, advanced management and technology; while small factories have higher costs and higher prices due to various restrictions. < Br >
And the market price changes at any time. If you want to know the exact market price, you should consult chemical product suppliers, chemical trading platforms, or related industry personnel to obtain the latest and accurate information.