3 Bromopyridine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

3-Bromopyridine-2-carbonitrile

    Specifications

    HS Code

    680726

    Name 3-Bromopyridine-2-carbonitrile
    Molecular Formula C6H3BrN2
    Molecular Weight 183.005 g/mol
    Cas Number 7252-83-7
    Appearance Off-white to light yellow solid
    Melting Point 65 - 69 °C
    Boiling Point 268.6 °C at 760 mmHg
    Density 1.69 g/cm³
    Solubility Soluble in organic solvents like dichloromethane, chloroform
    Purity Typically available in high purity (e.g., 95%+)
    Flash Point 116.2 °C

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 3-Bromopyridine-2-carbonitrile?
    3-Bromopyridine-2-formonitrile is an organic compound. It has unique chemical properties.
    Looking at its structure, the bromine atom and the cyanyl group are connected to the pyridine ring. Due to the certain electronegativity of the bromine atom, the distribution of the molecular electron cloud is disturbed, which affects the reactivity. Bromine atoms can participate in the nucleophilic substitution reaction. With its good departure properties, they are easily replaced by suitable nucleophilic reagents. In case of hydroxyl negative ions, they can form corresponding hydroxyl substitutes; interact with amino reagents, or obtain amino-substituted products, which is crucial for the construction of various pyridine derivatives.
    Cyanyl also has active chemistry. It can be hydrolyzed, and under acidic or basic conditions, the cyanyl group can be converted into a carboxyl group, and then the pyridine carboxylic acid compounds can be synthesized. Such compounds are widely used in the fields of medicine, pesticides, etc. Cyanyl groups can also participate in the reduction reaction to obtain aminomethyl pyridine derivatives, which add new structural units to organic synthesis.
    Furthermore, the conjugated system of the pyridine ring imparts certain stability and electron delocalization characteristics to the molecule, which affects the selectivity of the check point of nucleophilic and electrophilic reactions. In the electrophilic substitution reaction, the reaction is mostly affected by the localization effect of bromine and cyano groups, and the reaction occurs at a specific location. In conclusion, 3-bromopyridine-2-formonitrile has active and diverse chemical properties due to its functional groups and pyridine ring structures, which is of great significance in the field of organic synthesis and lays a foundation for the creation of new functional materials and drug lead compounds.
    What are the common synthetic methods of 3-Bromopyridine-2-carbonitrile?
    The common synthesis methods of 3-bromopyridine-2-formonitrile have been known for a long time. First, pyridine is used as the starting material. First, pyridine is substituted with bromine under appropriate conditions to introduce bromine atoms. This process requires precise control of the reaction temperature, time and proportion of reactants, so that bromine atoms are just substituted at the 3rd position of the pyridine ring. Then, under specific reagents and reaction conditions, cyano groups are introduced at the 2nd position, which can be achieved by suitable nucleophilic substitution reactions. The choice of reagents and reaction environment is extremely critical, which affects the purity and yield of the product.
    Second, 2-cyanopyridine is used as the starting material. On this basis, the bromination reaction at position 3 is achieved by specific brominating reagents under suitable solvents and reaction conditions. Attention should be paid to selecting mild and selective brominating reagents to avoid adverse effects on cyanyl groups, and to regulate the reaction parameters to obtain better synthesis results.
    Third, the target molecule can be gradually constructed from the pyridine derivatives containing suitable substituents through multi-step reactions. According to the different structures of starting materials, the reaction route is rationally designed, and the synthesis of 3-bromopyridine-2-formonitrile is gradually achieved through a series of organic reactions such as substitution, addition, and elimination. This process requires high requirements for the planning of reaction steps and the optimization of reaction conditions in each step.
    3-Bromopyridine-2-carbonitrile in what areas
    3-Bromopyridine-2-formonitrile has many uses in various fields. This compound is a key raw material in the field of pharmaceutical creation. The structure of genopyridine and nitrile groups endows it with unique biochemical activities. Physicians use it to develop antibacterial and anti-inflammatory drugs, or to provide an opportunity for the creation of new anti-cancer drugs. Because it can combine with specific targets in organisms, interfere with pathological processes, and then have therapeutic effects.
    In the field of materials science, 3-bromopyridine-2-formonitrile also has extraordinary properties. It can be integrated into polymer materials by chemical synthesis to improve the properties of materials. For example, it can enhance the stability and durability of materials, and can be used in the preparation of coatings, plastics and other materials, or it can optimize its quality and make it more suitable for different environments.
    Furthermore, in the field of organic synthetic chemistry, this compound is an important intermediate. Chemists can use the activity of bromine atoms and nitrile groups to carry out various chemical reactions. Through nucleophilic substitution, addition and other reactions, more complex organic molecular structures can be constructed, paving the way for the synthesis of new organic compounds, and promoting the progress and development of organic synthetic chemistry.
    Overall, 3-bromopyridine-2-formonitrile has shown important application value in many fields such as medicine, materials and organic synthesis, and has made great contributions to the development of related fields.
    What is the market price of 3-Bromopyridine-2-carbonitrile?
    The market price of 3-bromopyridine-2-formonitrile is difficult to come to a conclusion. The price of 3-bromopyridine-2-formonitrile is often influenced by many factors, which is like a changing situation and is elusive.
    The first to bear the brunt is the cost of production. The preparation of this compound requires specific raw materials and exquisite processes. The price of raw materials often varies from time to time. If raw materials are scarce, or their acquisition and refining costs are high, the cost of 3-bromopyridine-2-formonitrile will rise, and the market price will also rise. And the simplicity of the process is also related to the production cost. If the process is complicated, many steps and precision instruments are required, and manpower and material resources are consumed, the price should be high.
    Furthermore, the supply and demand relationship in the market has a deep impact on its price. If the market has strong demand for 3-bromopyridine-2-formonitrile, such as in specific fields such as medicine and pesticides, the demand for R & D or production increases sharply, and the supply is relatively insufficient, just like the trend of water, the price will rise. On the contrary, if the supply exceeds the demand and the market is saturated, the price may fall in order for merchants to sell the goods.
    In addition, the situation of industry competition also affects its price. Many manufacturers compete for the market. If the competition is fierce, each manufacturer will compete for a share, or they will use the price as a weapon to reduce the price and promote. However, if the market is monopolized by a few manufacturers, its pricing power is in control, and the price may be stable and higher.
    There are more policies and regulations and the international trade situation, which should not be underestimated. Stringent environmental protection policies may lead to limited production, increased costs, and prices are affected by them. Tariff adjustments and trade barriers in international trade affect their import and export, which in turn affects market prices.
    Therefore, in order to know the exact market price of 3-bromopyridine-2-formonitrile, it is necessary to gain real-time insight into the raw material market, pay attention to the dynamics of supply and demand, clarify the industry competition landscape, and pay attention to changes in policies and regulations and international trade, in order to obtain more accurate price information, so as not to misjudge.
    What are 3-Bromopyridine-2-carbonitrile storage conditions?
    3 - Bromopyridine - 2 - carbonitrile is an organic compound, and its storage conditions are quite important. This compound should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of reaction or deterioration due to excessive temperature. The dry state can avoid moisture hydrolysis or chemical changes with water vapor. Good ventilation can drive away volatile gases that may accumulate, and keep the environment safe.
    When storing, be sure to keep away from fire and heat sources. Fire and heat can easily lead to combustion or trigger violent reactions, causing dangerous accidents. And should be stored separately from oxidizing agents, acids, bases, etc. Because of their active chemical properties, contact with their substances or chemical reactions will have unpredictable consequences.
    The container must be tightly sealed to prevent leakage. If exposed to air or interacting with air components, it will affect the quality. After taking it, it should also be sealed in time to ensure its stability. In addition, the storage area should be equipped with suitable materials to contain leaks. In case of leakage, it can be dealt with in time to minimize harm. In short, follow the above storage conditions to ensure the quality and storage safety of 3-Bromopyridine-2-carbonitrile.