3 Bromopyridine 2 4 Diol
pyridine pyrrole pyrazine piperidine piperazine

3-Bromopyridine-2,4-diol

    Specifications

    HS Code

    207661

    Chemical Formula C5H4BrNO2
    Molar Mass 189.995 g/mol
    Appearance Solid (predicted)
    Boiling Point Decomposes
    Melting Point 187 - 190 °C
    Density 1.925 g/cm³ (predicted)
    Solubility In Water Slightly soluble
    Pka 2.65 (predicted)
    Logp -0.24 (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 3-Bromopyridine-2,4-diol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3-Bromopyridine-2,4-diol?
    3 - Bromopyridine - 2,4 - diol is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, which is relatively stable at room temperature and pressure.
    This compound contains a bromine atom and two hydroxyl groups, giving it specific reactivity. Bromine atoms can participate in nucleophilic substitution reactions because of their certain electronegativity, making the carbon atoms connected to it partially positively charged and vulnerable to attack by nucleophiles. For example, it can be substituted with nucleophiles such as sodium alcohol and amines to generate new nitrogen-containing or oxygen-containing derivatives, which is very important for the preparation of complex pyridine compounds in organic synthesis.
    Furthermore, its two hydroxyl groups are also active. Hydroxyl groups can participate in esterification reactions, react with carboxylic acids or anhydrides under the action of catalysts to form ester compounds, which can be used to modify molecular structures and change their physical and chemical properties. At the same time, hydroxyl groups can undergo dehydration reactions. Under appropriate conditions, two molecules of the compound can be dehydrated and condensed to form ether structures.
    In addition, 3-Bromopyridine-2,4-diol can form intramolecular or intermolecular hydrogen bonds due to the presence of hydroxyl groups. Intramolecular hydrogen bonds affect the spatial structure and stability of compounds, while intermolecular hydrogen bonds have significant effects on their physical properties such as melting point, boiling point and solubility. In polar solvents, because they can form hydrogen bonds with solvent molecules, they have good solubility.
    In summary, 3-Bromopyridine-2,4-diol is widely used in the field of organic synthesis due to its bromine atom and hydroxyl properties, and can be used as a key intermediate to prepare a variety of compounds with biological activity or special functions.
    What are the main uses of 3-Bromopyridine-2,4-diol?
    3 - Bromopyridine - 2,4 - diol is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of drugs in the field of medicinal chemistry. Due to the special chemical structure of this compound, a variety of biologically active drug molecules can be derived through a specific chemical reaction path, such as some antibacterial and antiviral drugs. By modifying and modifying its structure, the interaction between the drug and the biological target can be precisely adjusted, thereby improving the efficacy and selectivity of the drug.
    In the field of materials science, 3 - Bromopyridine - 2,4 - diol also has its uses. It can be used as a raw material for the preparation of functional materials, such as organic materials with specific optoelectronic properties. In the process of organic synthesis, its bromine atoms and hydroxyl groups can participate in a variety of reactions, such as nucleophilic substitution reactions, coupling reactions, etc., to build complex organic molecular structures and lay the foundation for the creation of new materials. It is expected to be applied to optoelectronic devices, such as organic Light Emitting Diodes, solar cells and other fields, endowing materials with unique optical and electrical properties.
    In addition, in the field of pesticide chemistry, derivatives made from a series of reactions using this as a starting material may have biological activities such as insecticides and weeds, which can provide an effective means for pest control in agricultural production and help improve the yield and quality of crops.
    What are the synthesis methods of 3-Bromopyridine-2,4-diol?
    3 - Bromopyridine - 2,4 - diol is an important organic compound, and there are many methods for its synthesis. The common method is to use pyridine derivatives as the starting material.
    First, pyridine containing suitable substituents can be introduced into bromine atoms through halogenation reaction, and then hydroxylation reaction can be used to introduce hydroxyl groups at specific positions. For example, pyridine is brominated first, the reaction conditions are controlled, and the bromine atoms are precisely replaced to the target position, and then the hydroxylation is achieved by using suitable reagents and conditions to obtain 3 - Bromopyridine - 2,4 - diol. In this process, the halogenation reaction needs to select a suitable halogenated reagent and reaction environment to ensure the accuracy of the substitution position; the hydroxylation step needs to consider factors such as reagent activity, reaction temperature, time, etc., to ensure the successful introduction of hydroxyl groups and the purity of the product.
    Second, the strategy of gradually constructing pyridine rings can also be used. Small molecules containing bromine and potential hydroxyl functional groups are synthesized first, and then pyridine rings are constructed by cyclization. In this approach, the synthesis of small molecules requires careful design of reaction routes to ensure the relative position and activity of functional groups; during cyclization, the reaction conditions should be regulated to promote smooth cyclization of molecules, while avoiding side reactions, in order to achieve higher yield and purity.
    In addition, the improved method reported in the literature can also be used for reference. Many researchers have explored the synthesis of similar compounds, and their experience and improvement strategies can be used as a reference. By optimizing the reaction conditions and using new catalysts or reagents, it is expected to improve the synthesis efficiency and quality of 3-Bromopyridine-2,4-diol. In short, the synthesis of this compound requires comprehensive consideration of many factors such as starting materials, reaction steps, and condition control, and satisfactory results can be obtained through repeated experiments and optimization.
    What should I pay attention to when storing and transporting 3-Bromopyridine-2,4-diol?
    3 - Bromopyridine - 2,4 - diol is a chemical substance that requires careful attention in many aspects when storing and transporting.
    Store first. This substance is quite sensitive to environmental conditions and is first dry. Humid gas can easily cause it to deteriorate, so it should be placed in a dry place, away from water sources, and the surrounding humidity should be controlled at a low level. Temperature is also critical, not too high or too low, usually at room temperature. Due to extreme temperatures or chemical reactions, it will affect its chemical properties. Furthermore, it is necessary to prevent it from coming into contact with other chemicals, especially those with strong oxidizing or reducing properties, so as not to cause dangerous reactions. The storage place should be well ventilated to avoid the accumulation of harmful gases.
    As for transportation, the packaging must be tight. Appropriate packaging materials should be selected to ensure that they are not affected by vibrations and collisions during transportation to prevent leakage. Transportation vehicles should be clean and free of other substances that may react with them. Transport personnel should also be familiar with their characteristics and emergency treatment methods. In the event of an accident, they can respond quickly and correctly. Transportation route planning should also pay attention to avoid densely populated areas and environmentally sensitive places to prevent leakage from causing serious harm to people and the environment. In this way, the safety and stability of 3-Bromopyridine-2,4-diol during storage and transportation should be guaranteed.
    What is the market price of 3-Bromopyridine-2,4-diol?
    3 - Bromopyridine - 2,4 - diol is a chemical substance whose market price varies due to a variety of factors. The complexity of the synthesis or extraction process of this substance, the amount of market demand for it, and the size of the production scale all affect its price.
    If the synthesis process is complicated, rare or expensive raw materials are required, or the operating conditions are harsh, the production cost will rise, and the market price will also rise. Furthermore, if the market demand for this substance is strong and the supply is limited, the state of supply will push up the price; conversely, if the demand is low and the supply is sufficient, the price may decline.
    However, there is no conclusive uniform pricing in the market today. Based on past transactions and market conditions, the price range is relatively wide. For transactions with average purity and small batches, the price per gram may range from tens of yuan to hundreds of yuan; if the purity is extremely high, or the purchase volume is quite large, the unit price may be significantly reduced due to the scale effect, from a few yuan to a few tens of yuan per gram. However, this is only a rough estimate. The real price needs to be consulted with chemical raw material suppliers in detail, or the recent transaction data on the relevant chemical product trading platform can be obtained. Price information close to market conditions can be obtained.