3 Bromoh Pyrazolo 1 5 A Pyridine 5 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

3-bromoH-pyrazolo[1,5-a]pyridine-5-carboxylic acid

    Specifications

    HS Code

    710621

    Chemical Formula C8H6BrN3O2
    Molecular Weight 254.057 g/mol
    Appearance Solid (predicted)
    Boiling Point 534.9±50.0 °C at 760 mmHg (predicted)
    Melting Point N/A
    Density 1.93±0.1 g/cm3 at 20 °C (predicted)
    Pka 2.52±0.10 (predicted)
    Logp 1.02 (predicted)
    Solubility Soluble in organic solvents (predicted)
    Flash Point 277.3±30.1 °C (predicted)

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    General Information
    Where to Buy 3-bromoH-pyrazolo[1,5-a]pyridine-5-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 3-bromoH-pyrazolo[1,5-a]pyridine-5-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid
    3-BromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid is an organic compound. Its chemical structure is composed of several parts.
    First look at its core structure, containing the ring system of pyrazolo [1,5-a] pyridine. Pyrazolo [1,5-a] pyridine ring system is formed by fusing the pyrazolo ring with the pyridine ring. The pyrazolo ring has a dinitrogen atom and is merged with the pyridine ring at a specific position. This fused structure endows the compound with unique physical and chemical properties.
    In this compound, bromine atoms are attached at the 3rd position. The bromine atom is a halogen element with certain electronegativity. Its connection to the ring will affect the electron cloud distribution of the molecule, which in turn affects the reactivity and polarity of the compound.
    Furthermore, there is a carboxyl group (-COOH) attached to the 5 position. The carboxyl group is acidic because it can ionize hydrogen ions. This property makes the compound able to participate in many acid-base reactions, and can also react with compounds containing hydroxyl groups, amino groups and other functional groups such as esterification and amidation.
    In summary, the chemical structure of 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid combines the pyrazolo [1,5-a] pyridine ring system, bromine atom and carboxylic group, and the interaction of each part determines its chemical behavior and properties.
    What are the main uses of 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid
    3-Bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acid (3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acid) is a crucial compound in the field of organic synthesis, and has a wide range of uses in medicine, pesticides and materials science.
    In the field of medicine, this compound is often used as a key intermediate to create various biologically active drugs. Due to its unique chemical structure, it can interact with specific biological targets, thereby exhibiting potential pharmacological activity. For example, in the development of anti-tumor drugs, chemists are expected to obtain new compounds that have inhibitory effects on tumor cell growth by modifying and optimizing their structures. By precisely adjusting the position and type of substituents, the affinity and selectivity of drugs and tumor cell targets can be improved, thereby enhancing the efficacy and reducing the damage to normal cells.
    In the field of pesticides, 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acids also have important applications. It can be used as a starting material for the synthesis of high-efficiency and low-toxicity pesticides. For example, through a series of chemical reactions, it can be converted into an insecticide with a special mechanism of action against pests. Such pesticides may be able to interfere with the nervous system, respiratory system or other key physiological processes of pests, achieve efficient prevention and control of pests, and reduce the adverse effects on the environment and non-target organisms, which is in line with the development needs of modern green pesticides.
    In terms of materials science, this compound can be used to prepare functional materials. Due to its structural properties, it can endow materials with unique photoelectric properties. For example, in the synthesis of organic Light Emitting Diode (OLED) materials, the introduction of this compound structural unit may be able to optimize the properties of materials such as luminous efficiency, stability and color purity, providing assistance for the further development of OLED technology.
    In summary, 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acids play an indispensable role in the fields of medicine, pesticides and materials science due to their diverse chemical properties and reactivity, and promote technological innovation and development in various fields.
    What are the synthesis methods of 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid
    3 - bromoH - pyrazolo [1,5 - a] pyridine - 5 - carboxylic acid is an important organic compound, and its synthesis method is very important. The synthesis of this compound often follows the classical organic synthesis method and is achieved through several steps.
    The first step is often to use suitable pyridine derivatives as starting materials. Due to the stable structure of the pyridine ring and the check point of reactivity, bromine atoms can be introduced at specific positions in the pyridine ring through halogenation reaction. This step requires fine regulation of reaction conditions, such as reaction temperature, reaction time and proportion of reactants. If the temperature is too high, it may cause the formation of polyhalogenated by-products; if the temperature is too low, the reaction rate will be delayed and the yield will be affected. < Br >
    Second step, the structure of pyrazolopyridine is constructed by specific reaction conditions. This process often involves cyclization reaction, or requires specific catalyst assistance. The choice of catalyst is crucial, and its activity and selectivity are directly related to the success or failure of the cyclization reaction and the purity of the product. And the properties of the reaction solvents also affect, and different solvents have different solubility and reactivity of the reactants.
    Furthermore, there are various strategies for the introduction of carboxyl groups. Either by oxidation of specific functional groups or by nucleophilic substitution reaction, carboxyl-containing reagents are introduced into the molecule. During oxidation reactions, attention should be paid to the strength and selectivity of the oxidizing agent to prevent excessive oxidation. Nucleophilic substitution reactions should pay attention to the matching of nucleophilic reagent activity and reaction conditions.
    After each step of the reaction, separation and purification operations are required to remove by-products and unreacted raw materials. Common separation methods include column chromatography and recrystallization. Column chromatography achieves separation according to the polarity difference of the compound, and recrystallization achieves purification by different solubility of the compound at different temperatures. After multi-step reaction, separation and purification, the final product is 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid. The synthesis process requires strict control of reaction conditions, precise selection of reagents and catalysts, and skilled use of separation and purification technology to obtain the product with ideal yield and purity.
    What are the physical properties of 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid
    3-BromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid, that is, 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acid. Although this physical property is not detailed in ancient books, it can be inferred according to today's chemical theory.
    Its appearance is often in a solid state, due to its intermolecular force and structure. The number of melting points varies depending on its purity and crystal form, and is usually in a certain temperature range. This substance has unique chemical activity due to its containing bromine atoms, pyridine rings and carboxyl groups. Bromine atoms can participate in various reactions such as nucleophilic substitution, while carboxyl groups are acidic, can form salts with alkali substances, and can also participate in esterification and other reactions.
    In terms of solubility, because it contains polar carboxyl groups, it may have a certain solubility in polar solvents such as water, but it also has a certain solubility in non-polar solvents due to the existence of pyridine rings and pyrazole rings. It depends on the interaction between solvent polarity and molecules. Its stability is acceptable under conventional conditions. However, when exposed to high temperatures, strong acids and bases or specific chemical reagents, the molecular structure may change, and reactions such as decomposition and rearrangement occur.
    In summary, the physical properties of 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acids are determined by their molecular structure, and are key considerations in chemical research and related applications.
    What is the market outlook for 3-bromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid
    3-BromoH-pyrazolo [1,5-a] pyridine-5-carboxylic acid, Chinese name or 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acid. This compound has good prospects in the field of chemical raw materials and pharmaceutical research and development.
    In the chemical raw material market, with the continuous expansion of the chemical industry, the demand for characteristic organic compounds is increasing. 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acid, as a key organic synthesis intermediate, is of great significance in the preparation of new materials and fine chemicals. With the advancement of science and technology, chemical products are moving towards high-end and refinement. As an important building block for building complex organic structures, the demand for this compound is expected to rise steadily.
    In the field of pharmaceutical research and development, nitrogen-containing heterocyclic compounds have always been a hotspot in pharmaceutical chemistry research. The unique heterocyclic structure of 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acids endows them with diverse biological activities. Many studies have shown that this type of structure has great potential for the development of anti-tumor, anti-inflammatory, antibacterial and other drugs. With the rapid development of pharmaceutical science and technology, the demand for the exploration and synthesis of novel drug molecules has increased sharply. As an important synthetic precursor, 3-bromo-H-pyrazolo [1,5-a] pyridine-5-carboxylic acids may play an increasingly key role in the development of innovative drugs, contributing significantly to the cause of human health.