3-(Bromoacetyl)pyridine hydrobromide

3 - (bromoacetyl) pyridine hydrobromide has a wide range of uses. In the field of organic synthesis, it is an important intermediate. It can be used to create various nitrogen-containing heterocyclic compounds, which have key effects in medicine, pesticides, materials science and many other aspects.
In the field of medicine, using it as a starting material, it can synthesize a variety of biologically active drug molecules. The structural properties of the pyridine ring and bromoacetyl groups can interact with specific targets in organisms, which will help to develop new therapeutic drugs, such as antibacterial, anti-inflammatory, and anti-tumor drugs, which are expected to bring great benefits to human health and well-being.
In the field of pesticides, pesticide products with high insecticidal and bactericidal properties can be synthesized through this. Through precise molecular design, using its chemical activity to create highly selective, low-toxic and environmentally friendly pesticides for pests and pathogens, in order to promote sustainable agricultural development and ensure crop yield and quality.
In the field of materials science, it can also be used. It can participate in the synthesis of functional polymer materials, giving materials special electrical, optical or mechanical properties. For example, preparing polymers with specific electrical conductivity properties for use in the field of electronic devices; or synthesizing materials with fluorescent properties for optical sensing, display technology, etc. In conclusion, 3- (bromoacetyl) pyridine hydrobromide has shown broad application prospects in many fields due to its unique chemical structure and activity, providing an important chemical basis for technological innovation and development in various fields.

The method of preparing 3- (bromoacetyl) pyridine hydrobromide has been described in many books in the past. The common method is to use pyridine as a base to react with bromoacetyl bromide in an appropriate solvent. If anhydrous dichloromethane is used as a solvent, pyridine and bromoacetyl bromide are mixed in a certain proportion, and slowly added dropwise at low temperature to prevent overreaction. After adding dropwise, gradually heat up to room temperature, and continue to stir to make the reaction sufficient. When the reaction is completed, the crude product can be obtained by washing with water, drying, and rotary steaming. After recrystallization with an appropriate solvent, a pure 3- (bromoacetyl) pyridine hydrobromide can be obtained.
There are those who use 3-acetylpyridine as the starting material. First, 3-acetylpyridine is reacted with bromine in glacial acetic acid, and bromine selectively replaces the α-hydrogen atom of the acetyl group to generate 3- (bromoacetyl) pyridine. The reaction process should be controlled by temperature and should not be too high to avoid side reactions. After the reaction is completed, it is neutralized, extracted, dried, etc., and then reacted with hydrobromic acid to form the target product 3- (bromoacetyl) pyridine hydrobromide.
Another method is to use 3-methylpyridine as the starting material. First, 3-methylpyridine is oxidized to 3-pyridinecarboxylic acid, and then 3-pyridinecarboxylic alcohol is obtained through esterification, reduction and other steps. Then 3-pyridinecarboxylic alcohol is treated with a brominating agent such as phosphorus tribromide to obtain 3-bromomethyl pyridine. Then it reacts with acetyl bromide and goes through a series of treatments to finally obtain 3 - (bromoacetyl) pyridine hydrobromide. All methods have their own advantages and disadvantages, and need to be carefully selected according to the actual situation, such as the availability of raw materials, cost, product purity, etc.

3 - (bromoacetyl) pyridine hydrobromide, this is an organic compound. Its physical properties are crucial and related to many practical applications.
When it comes to appearance, under normal temperature and pressure, it is mostly white to light yellow crystalline powder, which is easy to identify intuitively. And when the substance is in the solid state, the texture is more delicate, and the feel may be different from other substances.
The melting point is about 150-155 ° C. The characteristics of the melting point are of great significance in the purification, identification and temperature control of the substance during application. When the temperature approaches or reaches this range, the compound will gradually change from the solid state to the liquid state, and its intermolecular forces will also change.
In terms of solubility, it is soluble in polar solvents such as water, methanol, and ethanol. This property allows for the selection of suitable solvents according to needs when preparing solutions or performing related chemical reactions. Dissolved in water, it can form a uniform and dispersed system, which plays a basic supporting role in some reactions or analytical tests involving aqueous solutions.
As for the density, although the exact value varies slightly due to measurement conditions, it is roughly 1.8-2.0 g/cm ³. The property of density has important reference value in practical operations such as the measurement, storage, and transportation of substances. The physical properties of 3- (bromoacetyl) pyridyl hydrobromide, from appearance, melting point, solubility to density, play an indispensable role in the research and production process of chemical industry, medicine and other fields, providing a lot of operation and application basis for related workers.

3 - (bromoacetyl) pyridine hydrobromide is an important compound in organic chemistry, and many matters must be paid attention to when storing and transporting.
First, when storing, place it in a cool, dry and well-ventilated place. Because the compound is quite sensitive to humidity and temperature, high temperature or humid environment can easily cause it to deteriorate. If the humidity is too high, it may cause moisture decomposition, causing its purity to be damaged; if the temperature is too high, it may accelerate its chemical reaction and change its chemical properties.
Second, it needs to be kept away from fire and heat sources. Because of its certain chemical activity, in case of open fire, hot topic or dangerous accidents such as combustion or even explosion, it will endanger the safety of the storage place and surrounding areas.
Third, it should be stored separately from oxidants, alkalis, etc., and should not be mixed. Due to its chemical structure characteristics, contact with oxidants, or severe oxidation reaction; encounter with alkalis, or chemical reaction occurs, causing the compound to deteriorate and or produce dangerous products.
Fourth, when transporting, be sure to ensure that the container is well sealed to prevent leakage. If leakage occurs, not only will material loss occur, but the compound may cause pollution to the environment, contact with human body or endanger health. During transportation, follow relevant regulations, choose suitable transportation tools and conditions, and ensure transportation safety.
Fifth, storage and transportation sites should be equipped with suitable emergency treatment equipment and protective equipment. In the event of an accident, such as a leak or fire, personnel can take timely and effective measures to reduce the risk and ensure their own safety.

I don't know the market price of "3 - (Bromoacetyl) pyridine hydrobromide". This compound is not a well-known common general-purpose compound, and its price is determined by a variety of reasons.
First, the purity has a great impact. If the purity is very high, it is suitable for the key steps of fine synthesis or scientific research, and the price must be high; if the purity is slightly lower, it is only used for the preliminary exploration of ordinary experiments, and the price may be slightly reduced.
Second, the ease of preparation is also the key. If the synthesis requires complicated steps, expensive reagents or special conditions, the cost will increase and the price will be high.
Third, the market supply and demand situation is related to the price. If the demand is strong and the supply is limited, if there is a sudden increase in demand for this product in some emerging research fields, the price will rise; if the supply exceeds the demand, the price will tend to fall.
Fourth, the price is different due to the difference in suppliers. Well-known large enterprises, strict product quality control, or because of brand and service, the price is higher; small suppliers compete for the market, or have low-price strategies.
For the exact price, you can consult chemical reagent suppliers, such as Sinopharm Group Chemical Reagent Co., Ltd., search banner reagent company, etc. They often quote based on real-time conditions. You can also browse professional chemical e-commerce platforms, or communicate with industry peers to know their approximate price range.