3-Bromo-5-(imidazol-1-yl)pyridine

3-Bromo-5- (imidazole-1-yl) pyridine, this is an organic compound. Its chemical properties are unique, and it has some of the characteristics of pyridine and imidazole.
Let's talk about the pyridine ring first. The pyridine ring is aromatic, and the presence of nitrogen atoms makes its electron cloud uneven and alkaline. The bromine atom at position 3 has high chemical activity and can participate in many nucleophilic substitution reactions. Because of its carbon-bromine bond, the bromine atom has strong electronegativity, which makes the carbon atom partially positively charged and vulnerable to attack by nucleophilic reagents. For example, when reacted with sodium alcohol, bromine atoms can be replaced by alkoxy groups to form corresponding ether compounds; when reacted with amines, nitrogen-containing derivatives can be formed, which is widely used in the construction of complex organic molecular structures.
Looking at the imidazole-1-group attached to the 5-position, the imidazole ring is also aromatic and has two nitrogen atoms, one of which is connected to pyridine at the 1-position. The nitrogen atom of the imidazole ring can participate in the formation of hydrogen bonds, which affects the physical and chemical properties of the compound. Under acidic conditions, the nitrogen atom of the imidazole ring can be protonated, changing the charge distribution and solubility of the entire molecule. At the same time, imidazole-1-group can participate in the reaction as a nucleophile or ligand. In transition metal-catalyzed reactions, it can coordinate with metal ions to stabilize the active centers of metals and promote the reaction.
The chemical properties of this compound make it potentially useful in pharmaceutical chemistry, materials science and other fields. In pharmaceutical chemistry, its structure can be modified to obtain compounds with specific biological activities; in materials science, its reactivity can be used to construct functional polymer materials.

3 - Bromo - 5 - (imidazol - 1 - yl) pyridine, Chinese name 3 - bromo - 5 - (imidazol - 1 - yl) pyridine, this compound has a wide range of uses and is often a key intermediate for the creation of new drugs in the field of medicinal chemistry. Due to its unique chemical structure, it can participate in a variety of chemical reactions and help build molecular structures with specific biological activities. For example, when developing targeted drugs for specific diseases, it can be used to precisely interact with targets in vivo to demonstrate therapeutic efficacy.
It also has important uses in the field of materials science. It can be modified by specific reactions to impart novel properties to materials, such as improving optical and electrical properties of materials. In the preparation of organic optoelectronic materials, with its structural properties, it may improve the charge transport ability of materials, enhance the photoelectric conversion efficiency, and contribute to the optimization of the performance of organic Light Emitting Diodes, solar cells and other devices.
In the field of chemical synthesis, as a key raw material, it provides the possibility for the construction of complex organic molecules. With its active check point, it can carry out coupling reactions, substitution reactions, etc., expand the complexity of molecular structures, and synthesize organic compounds with special functions and structures, which contribute to the development of organic synthesis chemistry.

3 - Bromo - 5 - (imidazol - 1 - yl) pyridine is an important organic compound, and its synthesis method follows the path of classical organic synthesis in the past.
The first is pyridine, which is aromatic, and the electron cloud on the ring is unevenly distributed, and a substituent can be introduced at a specific position. Here, a bromine atom is introduced at the 3rd position of the pyridine ring, and an imidazole - 1 - group is introduced at the 5th position.
First, pyridine is reacted with a brominating agent such as bromine under suitable conditions. Or in the presence of Lewis acid catalysis, such as aluminum trichloride, in an inert solvent, such as dichloromethane, the temperature and reaction time can be controlled, and the hydrogen at the 3-position of pyridine can be replaced by a bromine atom to obtain 3-bromopyridine.
Then 3-bromopyridine is used as a substrate to react with imidazole. Usually, the nitrogen atom of imidazole is nucleophilic and can undergo nucleophilic substitution with the 3-position bromine of 3-bromopyridine. The help of alkalis, such as potassium carbonate, is often required in an organic solvent such as N, N-dimethylformamide, heated and stirred to make the reaction proceed smoothly. The alkali can capture the hydrogen on imidazole nitrogen, enhance its nucleophilicity, and promote the efficient occurrence of nucleophilic substitution reactions, resulting in the final production of 3-Bromo-5- (imidazol-1-yl) pyridine.
There are also improved methods, such as the use of transition metal catalysis, which can improve the selectivity and efficiency of the reaction. Taking palladium catalysis as an example, suitable palladium catalysts such as tetra (triphenylphosphine) palladium, in the presence of ligands, can make the reaction conditions milder, and the product purity is better, and the yield is also improved. These synthesis methods have been refined with the development of organic chemistry, aiming to obtain target compounds more efficiently and green.

I don't have the exact price of 3 - Bromo - 5 - (imidazol - 1 - yl) pyridine in the market. However, if you want to know its price, you can follow several ways. First, visit the official website of the chemical supplier, such sites often list the price of the product, or have different prices depending on the purchase quantity and purity. Second, dial the phone and ask each supplier to discuss with their sales specialist, you can get accurate quotations, and you can inquire about discounts and delivery dates. Third, refer to the chemical product trading platform, which brings together multiple suppliers, and the price is clear at a glance, which is easy to compare. In addition, the price of this compound may be affected by the cost of raw materials, the difficulty of synthesis, and market supply and demand. If the price of raw materials is high, the synthesis is difficult, or the demand increases sharply and the supply is insufficient, the price will rise; otherwise, the price may drop. In short, to know the exact price, it is necessary to search for information and communicate with suppliers.

3-Bromo-5- (imidazole-1-yl) pyridine is a kind of organic compound. Its storage conditions are crucial to the quality and properties of this substance, which cannot be ignored.
This substance should be placed in a cool and dry place, away from direct sunlight. Cover sunlight exposure, or cause photochemical reactions to occur, damage its structure and change its properties. In a cool place, the temperature is constant, which can reduce the thermal movement of molecules and prevent the reaction from being accelerated due to excessive temperature, so as to maintain its chemical stability.
Dry environment is also key. Moisture in the air may interact with the compound, triggering reactions such as hydrolysis and causing it to deteriorate. Therefore, it is often necessary to store it in a sealed container to prevent moisture from invading.
When it is stored, it should be kept away from fire sources and oxidizing agents. This compound may be flammable, and it will be dangerous in case of fire; oxidizing agents can also react violently with the like, endangering safety.
In addition, in the place of storage, it should be clearly marked, and its name, nature and preservation should be noted. When using it, it is also necessary to follow the standard method to avoid misoperation causing its qualitative change or biological safety. In this way, the purpose of properly preserving 3-bromo-5- (imidazole-1-yl) pyridine can be achieved, so that it can be used in scientific research and production.