3-Bromo-5-chloropyridine-2-carboxylic acid

3-Bromo-5-chloropyridine-2-carboxylic acid, this is an organic compound. Its chemical properties are unique and acidic. Due to its carboxyl group, hydrogen ions can be dissociated under suitable conditions, and the corresponding carboxylate and water can be formed by neutralization reaction with alkali.
The presence of bromine and chlorine atoms in this compound gives it halogenated hydrocarbon properties. Bromine and chlorine atoms are highly active and can participate in many nucleophilic substitution reactions. For example, nucleophiles can attack carbon atoms connected to halogen atoms, and halogen atoms leave as leaving groups to form new organic compounds. The presence of
pyridine rings also significantly affects its chemical properties. The pyridine ring has certain aromatic and basic properties, and can react with acids to form pyridine salts. At the same time, the particularity of the electron cloud distribution on the pyridine ring affects the activity of the substituents connected to it, which makes the compound exhibit unique reactivity and selectivity in specific reactions.
In addition, the chemical properties of 3-bromo-5-chloropyridine-2-carboxylic acids are significantly affected by reaction conditions such as temperature, solvent, catalyst, etc. Under different reaction conditions, its participation in the reaction path and product may vary.

3-Bromo-5-chloropyridine-2-carboxylic acid, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate. Different functional groups can be introduced through specific reaction pathways to build complex active pharmaceutical ingredients, or to contribute to the synthesis of antibacterial and anti-inflammatory drugs.
In the field of pesticide chemistry, it also has important functions. With this as a starting material, new pesticides can be created, such as the design of highly selective and efficient insecticides for specific pests, or the development of fungicides that can resist plant diseases, helping to increase agricultural yield.
Furthermore, in the field of materials science, 3-bromo-5-chloropyridine-2-carboxylic acids can participate in the construction of functional organic materials. With its unique chemical structure, polymerization or other reactions endow materials with special properties such as photoelectric properties and adsorption properties, opening up new paths for the research and development of new materials.
In short, 3-bromo-5-chloropyridine-2-carboxylic acids play an indispensable role in many important chemical-related fields, and are of great significance for promoting technological innovation and development in various fields.

The synthesis method of 3-bromo-5-chloropyridine-2-carboxylic acid follows a number of paths. First, pyridine is used as the starting material, and bromine and chlorine atoms are added by halogenation reaction, and then carboxylation is carried out.
Take pyridine first, co-locate it with bromine and appropriate catalysts such as iron powder at low temperature, and bromine is selected to replace it in the pyridine ring to obtain bromine-containing pyridine. This step requires temperature control and agent ratio to avoid polybromination. Next, bromine-containing pyridine is used as the base and reacts with chlorine sources such as sulfoxide chloride and chlorine gas under specific conditions to make chlorine atoms enter the ring to obtain 3-bromo-5-chloropyridine. In this process, the solvent, temperature, and reaction time are all key, which are related to the purity and yield of the product.
Then, carboxylation of 3-bromo-5-chloropyridine. The Grignard reagent method can be used to prepare Grignard reagent with magnesium and 3-bromo-5-chloropyridine, and then hydrolyzed with carbon dioxide to obtain 3-bromo-5-chloropyridine-2-carboxylic acid. In this process, the Grignard reagent needs to be anhydrous and oxygen-free to prevent its decomposition.
Or, pyridine-2-carboxylic acid is used as the starting point and halogenated first. In a suitable solvent, pyridine-2-carboxylic acid is mixed with bromine and chlorine sources in sequence to control the reaction conditions, so that bromine and chlorine atoms occupy positions in sequence, and the target product can also be obtained. After each step of the reaction, separation and purification are often required, such as column chromatography and recrystallization, to remove impurities and extract the purity of the product.

I look at your question, but I am inquiring about the market price of 3-bromo-5-chloropyridine-2-carboxylic acid. However, this price is not constant and is actually influenced by various factors.
The first one to bear the brunt is the source of raw materials. If the raw materials for synthesizing this acid are abundant and cheap, the cost will drop, and its price may also decrease; on the contrary, the raw materials are scarce and expensive, and the cost will increase, and the price will rise.
Furthermore, the situation of market supply and demand has a great impact. If there are many applicants and few suppliers, merchants will raise prices due to the situation; if the supply exceeds the demand, the price will drop in order to sell inventory.
The roughness of the process is also the key. Sophisticated and advanced preparation technology may reduce costs and increase output, which also affects prices.
In addition, differences in regions and seasons can cause price fluctuations.
I don't have the exact market price. If you want to know, you can go to the chemical raw material trading market, consult chemical product suppliers, or check the industry information platform to get the latest and accurate price news.

3-Bromo-5-chloropyridine-2-carboxylic acid is an organic compound. When storing and transporting, the following things should be paid attention to:
First, the storage environment is the most critical. It should be stored in a cool, dry and well-ventilated place. This compound is quite sensitive to heat, and high temperature can easily cause it to decompose and deteriorate. If placed in a humid environment, moisture may react with the compound, which will damage its quality. Therefore, the warehouse temperature should be strictly controlled and the humidity should be kept within an appropriate range.
Second, avoid contact with incompatible substances. The compound has a certain chemical activity. Contact with strong oxidants, strong bases and other substances may cause violent chemical reactions, or even risk explosion. When storing, make sure that it is stored separately from such substances and take isolation measures.
Third, during transportation, the packaging must be stable and tight. Choose appropriate packaging materials to prevent the compound from leaking. Because the compound may be toxic and corrosive, once leaked, it will not only pollute the environment, but also pose a serious threat to the health of transporters.
Fourth, follow relevant regulations and standards. Whether it is storage or transportation, it must be strictly in accordance with national and local regulations on the management of hazardous chemicals. When transporting, corresponding qualifications are required, and transporters should also be familiar with the characteristics of the compound and emergency treatment methods.
Fifth, do a good job of marking and recording. Storage containers and transportation vehicles should clearly label the compound name, properties, hazards and other information. At the same time, make detailed records of the storage and transportation process for traceability and management.
In short, the storage and transportation of 3-bromo-5-chloropyridine-2-carboxylic acid should be treated with caution, and all factors should be considered to ensure that personnel safety, environmental safety and compound quality are not damaged.