3-Bromo-2-hydroxy-5-nitropyridine

3-Bromo-2-hydroxy-5-nitropyridine, this is an organic compound with unique chemical properties. In its structure, bromine atoms, hydroxyl groups and nitro groups are all connected to the pyridine ring.
Let's talk about its acidity and alkalinity first. Because it contains hydroxyl groups, under suitable conditions, hydroxyl hydrogen can be dissociated, making the compound acidic to a certain extent. The nitrogen atom of the pyridine ring has lone pairs of electrons and has a certain alkalinity, but its alkalinity is relatively weak.
Let's talk about its reactivity. Bromine atoms are highly active and prone to substitution reactions. When encountering nucleophiles, bromine atoms can be replaced by nucleophilic groups, such as reacting with sodium alcohol, bromine atoms may be replaced by alkoxy groups. < Br >
The nitro group is a strong electron-absorbing group, which reduces the electron cloud density of the pyridine ring, making the electrophilic substitution reaction on the ring more difficult. However, the nitro group itself can participate in a variety of reactions, such as reduction reaction. Under suitable conditions, the nitro group can be reduced to an amino group.
Hydroxy groups can not only reflect acidity, but also participate in esterification reactions. Reaction with acid anhydride or acid chloride can form corresponding ester compounds.
In addition, this compound may also undergo other reactions such as addition reactions on the ring, depending on the reaction conditions and the reagents encountered. Its chemical properties are rich and diverse, and it has important applications in the field of organic synthesis.

To prepare 3-bromo-2-hydroxy-5-nitropyridine, the following method can be used.
First, a suitable pyridine derivative is used as the starting material, such as 2-hydroxypyridine. It is first nitrified, placed in an appropriate amount of mixed acid (nitric acid and sulfuric acid are prepared in a specific ratio) system, and reacted at a suitable temperature. In the mixed acid, nitric acid is the nitrifying agent. Sulfuric acid can promote the production of nitroyl positive ions from nitric acid and improve the nitrification activity. Temperature control is crucial. If the temperature is too high, it is easy to cause side reactions such as polynitrification. If the temperature is too low, the reaction rate will be too slow. After this step, 2-hydroxy-5-nitropyridine can be obtained.
Then 2-hydroxy-5-nitropyridine is brominated. The bromine source is liquid bromine or bromine-containing reagents such as N-bromosuccinimide (NBS), and the reaction is initiated by heating or lighting in an organic solvent such as dichloromethane in the presence of an initiator such as benzoyl peroxide. Liquid bromine has higher activity, while NBS is relatively mild and easier to control. In the reaction, the initiator generates free radicals, which promote the substitution of bromine free radicals with specific positions on the pyridine ring to obtain the target product 3-bromo-2-hydroxy-5-nitropyridine.
After each step of the reaction, it needs to be separated and purified, such as extraction, column chromatography, etc., to remove impurities and extract the purity of the product to make the synthesis required. In this way, 3-bromo-2-hydroxy-5-nitropyridine can be synthesized.

3-Bromo-2-hydroxy-5-nitropyridine, this compound is used in many fields such as medicine, pesticides, materials science, etc.
In the field of medicine, as a key intermediate, it plays an extraordinary role in the development of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms. For example, in the development of anti-cancer drugs, the structure of this compound can be modified to precisely target specific receptors or enzymes in cancer cells, inhibit the proliferation of cancer cells, and bring new hope for overcoming cancer problems. In the research of antibacterial drugs, it can enhance the inhibitory activity of specific bacteria by adjusting its substituents, providing new ideas for solving the problem of bacterial drug resistance.
In the field of pesticides, 3-bromo-2-hydroxy-5-nitropyridine can be used to create highly efficient, low-toxicity and environmentally friendly pesticides. Thanks to its chemical properties, pesticides with high selectivity to pests and beneficial biological safety can be developed. For example, for some crop pests, pesticides developed based on this compound can interfere with the nervous system or metabolic processes of pests, achieve efficient control, and reduce the harm to the environment and non-target organisms, contributing to sustainable agricultural development.
In the field of materials science, this compound can participate in the synthesis of functional materials. For example, it is used to prepare materials with special optical and electrical properties. By introducing it into the structure of polymer materials, it can endow materials with unique photoelectric properties, demonstrate application potential in the fields of organic Light Emitting Diode (OLED), solar cells, etc., promote the continuous innovation and development of materials science, and lay the foundation for the research and development of new functional materials.

3-Bromo-2-hydroxy-5-nitropyridine, this is a chemical substance. Its storage conditions are crucial, which is related to the stability and safety of the substance.
According to chemical common sense, this substance should be stored in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature, humidity or lack of air circulation may cause chemical reactions, causing it to deteriorate or deactivate.
Furthermore, it should be kept away from fire sources and oxidants. This substance may be flammable. In case of open flames and hot topics, it is easy to burn and contact with oxidants. It is more likely to react violently and cause danger.
At the same time, the storage place should be separated from acids, bases and other chemical substances. Because its structure contains hydroxyl groups, nitro groups and other functional groups, contact with acid and alkali, or chemical reaction, affecting the quality of the substance.
Containers containing 3-bromo-2-hydroxy-5-nitropyridine must be well sealed to prevent them from contacting with moisture, oxygen and other components in the air, causing the composition to change. And the container material should be resistant to chemical corrosion and do not react with the substance.
Storage places should be clearly marked, indicating the name of the substance, danger and other information, so that personnel can identify and deal with emergency. Managers should regularly check storage conditions to ensure that environmental conditions are appropriate and that containers are free of leaks, so that 3-bromo-2-hydroxy-5-nitropyridine can be stored safely.

I think this 3 - Bromo - 2 - hydroxy - 5 - nitropyridine is a chemical substance. Its market price is difficult to determine. Because the market is changing, the price often changes with many factors.
First, the price of raw materials has a great impact. If the raw materials required for synthesizing this substance are easy to obtain and affordable, the cost is low, and the market price may not be high. However, if raw materials are scarce, or mining and refining are difficult, the price will be high, and the price of this substance will also rise.
Second, the preparation method is also important. An efficient and simple preparation process can reduce costs and make prices accessible to the people. If the preparation process is complicated, special equipment and harsh conditions are required, the cost will increase greatly, and the price will be high.
Third, market supply and demand determine the price. If the market demand for this material is strong, but the supply is limited, merchants may raise prices to obtain large profits. On the contrary, if the demand is low and the supply is excessive, merchants will sell it for promotion or reduce prices.
Fourth, manufacturers and brands also have an impact. Well-known manufacturers pay attention to quality and strict production management, and their product prices may be higher than ordinary manufacturers.
To know the exact market price, you should check the chemical product trading platform in detail and consult industry merchants or professionals to get an accurate number. It must not be based on fantasy alone, but on real-time market information.