3 Bromo 2 6 Dichloropyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Bromo-2,6-dichloropyridine

    Specifications

    HS Code

    847619

    Name 3-Bromo-2,6-dichloropyridine
    Molecular Formula C5H2BrCl2N
    Molecular Weight 226.88
    Appearance Solid (Typical)
    Melting Point 45 - 49 °C
    Boiling Point 239.6 °C at 760 mmHg
    Density 1.904 g/cm³
    Flash Point 98.7 °C
    Solubility Soluble in organic solvents like dichloromethane
    Purity Typically high - purity available in the market (e.g., 98%+)
    Cas Number 76626-75-8

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    General Information
    Where to Buy 3-Bromo-2,6-dichloropyridine in China?
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    Frequently Asked Questions

    As a leading 3-Bromo-2,6-dichloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Bromo-2,6-dichloropyridine?
    3-Bromo-2,6-dichloropyridine has a wide range of uses in the field of organic synthesis. Its primary use is in the preparation of pesticides. Based on it, a variety of high-efficiency pesticides can be prepared, which is of great help in agricultural pest control. For example, synthesizing insecticides with unique insecticidal mechanisms can accurately act on specific physiological links of pests, effectively eliminate pests and are environmentally friendly, reducing the damage of traditional pesticide residues.
    Furthermore, it also has an important position in the field of pharmaceutical synthesis. It can provide key intermediates for the synthesis of new drugs. With its special molecular structure and a series of chemical reactions, compounds with specific pharmacological activities can be constructed, and it is expected to develop innovative drugs for difficult diseases and benefit human health.
    Because of its halogen-containing atoms, it may be involved in the preparation of materials with special properties in materials science. If polymerized with other monomers, it may endow materials with unique electrical, optical or thermal properties, expand the scope of material applications, and show potential value in electronic devices, optical materials, etc. In short, 3-bromo-2,6-dichloropyridine has important uses in various fields, promoting the development of related industries and technological innovation.
    What are the synthesis methods of 3-Bromo-2,6-dichloropyridine?
    The synthesis method of 3-bromo-2,6-dichloropyridine is described in detail in ancient books.
    First, pyridine is used as the initial raw material and can be induced by halogenation. First, pyridine, bromine and chlorine are used under specific reaction conditions. In suitable solvents, such as inert organic solvents, control temperature, pressure and reaction time, so that bromine atoms and chlorine atoms replace hydrogen atoms on the pyridine ring in turn. The temperature control is very important. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow. The adjustment of pressure cannot be ignored, depending on the specific reaction. This way requires a fine grasp of the reaction process to obtain the target product. < Br >
    Second, it can be started from the corresponding pyridine derivative. First, pyridine derivatives with specific substituents are prepared, and then bromine and chlorine atoms are introduced through suitable conversion reactions. For example, select pyridine derivatives containing substituted groups and react with halogenated reagents in the presence of catalysts. The type and dosage of catalysts depend on the reaction rate and selectivity. Selecting a suitable catalyst can promote the reaction in the direction of generating 3-bromo-2,6-dichloropyridine.
    Third, the reaction path catalyzed by transition metals is also feasible. Using the unique catalytic properties of transition metal complexes, the reagents containing halogen atoms are coupled to pyridine substrates. In this process, transition metals can activate substrates and reagents, reducing the activation energy of the reaction. However, the selection of transition metals and the design of ligands are crucial. Ligands can affect the electron cloud density and steric resistance of metals, which in turn affect the selectivity and activity of the reaction. Optimization of reaction conditions, such as reaction solvents, types and dosages of bases, have a significant impact on the reaction results.
    All synthesis methods have advantages and disadvantages. The choice of initial raw materials, the difficulty of reaction conditions, the purity and yield of the product, etc., all need to be weighed. Experimenters should choose carefully according to their own conditions and needs in order to achieve the optimal synthesis effect.
    What are the physical properties of 3-Bromo-2,6-dichloropyridine?
    3-Bromo-2,6-dichloropyridine, this is an organic compound with unique physical properties. Its appearance is mostly white to light yellow crystalline powder, which is quite stable at room temperature and pressure.
    Looking at its melting point, it is between 46 and 48 ° C. This property allows the substance to change from solid to liquid at a specific temperature, which has a profound impact on its processing and application. In terms of boiling point, it is about 236-238 ° C. At this temperature, the substance will change from liquid to gaseous state, which is crucial in separation operations such as distillation.
    Solubility is also a key physical property. 3-Bromo-2,6-dichloropyridine is insoluble in water, but it is soluble in many organic solvents, such as dichloromethane, chloroform, ethanol, acetone, etc. This difference in solubility facilitates the selection of suitable solvents in chemical synthesis to promote the reaction, and also facilitates the separation and purification of the product.
    Furthermore, the density of the compound is about 1.82 g/cm ³, which reflects its unit volume mass and needs to be taken into account in operations involving metering and mixing. In addition, its low vapor pressure means that the degree of volatilization at room temperature is limited, which can reduce volatilization losses during storage and use, and ensure its stability and safety.
    These physical properties are interrelated and together determine the application mode and scope of 3-bromo-2,6-dichloropyridine in the fields of organic synthesis and drug development. Only by deeply understanding and making good use of these properties can we fully realize the value of this compound and achieve efficient and precise chemical operation and product preparation.
    What is the market price of 3-Bromo-2,6-dichloropyridine?
    3-Bromo-2,6-dichloropyridine, an important intermediate in the field of organic synthesis, is widely used in the preparation of many fine chemical products such as medicine and pesticides. Its market price fluctuates due to multiple factors, making it difficult to generalize accurate pricing.
    The first to bear the brunt, the market supply and demand relationship has a significant impact. If the market demand for medicines or pesticides containing this ingredient surges, and the supply is relatively scarce, the price will often rise; on the contrary, if the demand is low and the supply is excessive, the price will easily decline.
    Furthermore, the production cost also affects the price. The cost of raw materials is the first to bear the brunt. If the price of bromine, chlorine and other raw materials required for the preparation of 3-bromo-2,6-dichloropyridine rises, the cost of the product will increase and the price will increase accordingly. The complexity of the production process is closely related to it. If the process is cumbersome, involves multi-step reactions, harsh reaction conditions or requires high-end equipment and professional technology, the cost will increase and the price will also be high.
    In addition, product quality and purity have a great impact on the price. High-purity 3-bromo-2,6-dichloropyridine is in high-end application scenarios that are sensitive to impurities, and its price is naturally higher than that of low-purity products.
    Different suppliers offer different prices due to different production scales, technical levels, and operating costs. Suppliers with large-scale production may have low costs and competitive prices due to economies of scale; while small suppliers have high costs and high prices.
    Regional factors cannot be ignored. Prices vary in different regions due to different levels of economic development, logistics costs, and market competition. Economically developed regions have large demand but fierce competition, and prices may be relatively stable; while regions with inconvenient logistics or small markets may have prices affected.
    To know the exact market price, it is advisable to consult chemical raw material suppliers and distributors for details, or refer to real-time quotations on chemical product trading platforms to obtain more accurate price information.
    What are the precautions for 3-Bromo-2,6-dichloropyridine during storage and transportation?
    3-Bromo-2,6-dichloropyridine is a commonly used chemical raw material in organic synthesis. When storing and transporting, the following things should be paid attention to:
    First, the storage environment must be dry and cool. This compound is susceptible to moisture, moisture invades it, or causes it to undergo chemical reactions such as hydrolysis, which damages its quality. Therefore, it should be placed in a dryer or stored in an environment with a humidity lower than 40%. A cool place can reduce the risk of decomposition or other adverse reactions caused by excessive temperature. Generally speaking, the storage temperature should be maintained below 25 ° C.
    Second, it is necessary to isolate the air. The substance may react with oxygen, carbon dioxide and other components in the air, so it should be stored in a sealed container. Filling with inert gases such as nitrogen can further reduce its contact with air and maintain its chemical stability.
    Third, when transporting, ensure that the packaging is intact. Packaging materials need to have good pressure resistance and shock resistance to prevent the package from cracking due to collision and vibration during transportation, resulting in leakage of 3-bromo-2,6-dichloropyridine.
    Fourth, this compound has certain toxicity and irritation, and relevant safety procedures must be strictly followed whether it is stored or transported. Operators should wear protective clothing, gloves and goggles and other protective equipment to avoid direct contact. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment according to the specific situation.
    Fifth, the label must be clear. On the storage container and transportation package, its name, nature, danger warning and other information should be clearly marked so that relevant personnel can see it at a glance, and handle it with caution to avoid accidents.
    In short, proper storage and transportation methods are the key to ensuring the quality and safety of 3-bromo-2,6-dichloropyridine, and must not be taken lightly.