3-(BENZYLOXY)-5-BROMOPYRIDINE

3 - (carboxyl) - 5 - sulfonic acid group, the compound has the characteristics of both carboxyl and sulfonic acid groups. The carboxyl group is acidic and can be dissolved in water to make the solution acidic, with the general nature of acid, and can be neutralized and reversed to generate water. For example, acetic acid is an example, it is oxidized and reversed to produce acetic acid water. And the carboxyl group can be esterified and reversed, and the alcohol is catalyzed by acid to form an ester compound. This reaction is often used in the synthesis of alcohol, such as spices and spices.
The sulfonic acid group is also acidic, and its acidic carboxyl group is more acidic, which can be highly hydrolyzed in water. The presence of a sulfonic acid group allows the compound to have good water solubility. Due to the sulfonic acid properties, it is easy to form water molecules. Such as dodecylbenzene sulfonic acid, because of its sulfonic acid group, it can be soluble in water and is often used as an active ingredient for washing.

The same compound contains 3-carboxyl-5-sulfonic acid group, which is more acidic and has better water solubility. The degree of solubility of this compound in water is large, which can provide more molecules and make it have good solubility. In some applications, due to its good water solubility and acidity, it can be used for surface treatment of gold to remove oxides on the surface of gold. And because it has both functional and functional bases, it can provide more possibilities for synthetic synthesis, which can be used to synthesize special chemical compounds to meet the needs of materials science, material research and other fields.

3- (Amino) -5 -bromopyridine is an important intermediate in the field of organic synthesis. Its common synthesis methods are as follows:
1. ** Pyridine is used as the starting material **: Pyridine undergoes an amination reaction, an amino group is introduced, and then a bromine atom is introduced at a specific position through a bromination reaction. This path requires precise control of the reaction conditions in order to achieve regionally selective reactions. For example, under a suitable catalyst and reaction temperature, pyridine is fully reacted with an amination reagent, and then reacted with a brominating reagent to obtain the target product. The raw materials for this method are relatively common, but the reaction steps are relatively complicated, and the reaction conditions of each step need to be carefully optimized.
2. ** With the help of nitrogen-containing heterocyclic construction method **: using a suitable nitrogen-containing heterocyclic precursor as the starting material, a pyridine ring is constructed through a multi-step reaction, and amino and bromine atoms are introduced at the same time. This method can effectively improve the selectivity and yield of the target product by rationally designing the precursor structure. For example, a specific nitrogen-containing compound is selected to form a pyridine ring through cyclization reaction. During the reaction process, amino and bromine atoms are introduced in a timely manner according to demand. Although the starting material may not be widely available, this path can achieve the synthesis of the target product more efficiently, especially suitable for large-scale preparation.
3. Transition metal catalysis method: Under the action of transition metal catalysts, the reagent containing amino and bromine atoms is coupled with the pyridine derivative to generate 3- (amino) -5 -bromopyridine. This method has the advantages of mild reaction conditions and high selectivity. For example, taking palladium catalysts as an example, in the presence of specific ligands and bases, the corresponding halogenated pyridine derivatives are coupled with amination reagents. This method requires relatively low reaction equipment and can better control the reaction process, so it has certain application value in laboratory and industrial production.

The application of 3- (carboxyl) -5 -hydroxyl groups has been reflected in many fields, and it can be seen in detail in the "Tiangong Kaiwu".
In the pottery industry, these two functions are significant. In clay, the presence of carboxyl and hydroxyl groups affects the plasticity of clay. Carboxyl groups are hydrophilic and can absorb water molecules, which increases the distance between clay particles, thereby enhancing plasticity and making it easier to shape pottery billets. Hydroxyl groups can form hydrogen bonds with metal ions in clay to stabilize the clay structure. When fired, they help maintain the shape of the ceramic billet, reduce the possibility of deformation, and improve the quality of pottery.
The art of papermaking is also related to it. After raw materials such as wood are treated, the carboxyl and hydroxyl groups in cellulose can affect the properties of paper. Carboxyl groups can improve the water absorption of paper, hydroxyl groups can enhance the hydrogen bonding between cellulose, make paper fibers bond more tightly, improve paper strength and toughness, and make paper smooth and durable.
In the field of printing and dyeing, 3- (carboxyl) -5- (hydroxyl) has an extraordinary effect. Dye molecules contain such groups, which can chemically react with fabric fibers. Carboxyl and hydroxyl groups can combine with reactive groups on fibers to make dyes firmly adhere to fabrics, improve dyeing fastness, lasting and bright color, and both can adjust dye solubility and diffusion, and facilitate uniform dyeing.
Furthermore, in the field of medicine, many drug molecules contain this structure. Carboxyl and hydroxyl groups affect drug solubility, stability and biological activity. Appropriate proportions can optimize the absorption, distribution, metabolism and excretion of drugs in the body, improve the efficacy of drugs, and reduce toxic and side effects.
From the above, 3- (carboxyl) -5-hydroxyl groups play an important role in ceramics, papermaking, printing and dyeing, medicine, and many other fields, affecting the performance and quality of products in various industries. It is an indispensable chemical group.

There are three hydroxyl (amino) pentanal products today, what is the price of the market?
According to the "Tiangong Kaiwu", the price of various things often varies with time, place and quality. However, the book does not specify this trihydroxyl (amino) pentanal product, so it is difficult to determine its price.
The price of most goods in the world is determined by the thinness of the material, the difficulty of preparation, and the urgency of use. If the raw materials of this product are easy to obtain, and the preparation method is simple and labor-saving, the price may be inexpensive; if the raw materials are rare, the production method is difficult, and it takes a lot of effort, the price must be high.
And the distance of the place also depends on the price. If the product is located near the city and the freight province, the price is appropriate; if the place of origin is remote, it is difficult to transfer, the cost will increase, and the price will be high.
The need to use it is also the main reason. If people compete for it, and those who use it will increase the price; if there is little demand and few people ask for it, the price will be depressed.
Although "Tiangong Kaiwu" does not know the price of this trihydroxy (amino) pentanal, following the pricing principles mentioned in it, it can also be inferred that if the raw materials are widely distributed, the production method is easy, and there is no need for great heat, the price may be in the ordinary domain; if the raw materials are scarce, the preparation is complicated, and the user is eager, the price may be expensive, or it may be a treasure.

The storage conditions of 3- (carboxyl) -5 -hydroxyl are delicate, and it is necessary to pay attention to all elements of the environment.
The first is temperature. This substance should be stored in a cool place to avoid deterioration due to excessive temperature. Usually 0 to 5 degrees Celsius is the best environment, just like the state of cold spring, this temperature can slow down the movement of its molecules and maintain the stability of its structure.
The second is humidity. When avoiding moisture, if the humidity is too high, water vapor will easily adhere to it, causing its hydrolysis and other changes. Therefore, it should be placed in a dry place, with a relative humidity of 40% - 50%. It is just like the autumn climate, with less water and clear air.
And light. This object is afraid of light, especially direct exposure to strong light. If the light is sharp, it can break its chemical bonds and change its properties. Therefore, it should be hidden in a dark place or placed in a brown bottle, protected from light like a dark night, to preserve its authenticity.
And its storage place should be kept away from all kinds of chemicals to prevent it from touching and melting, causing unexpected changes. For example, when a gentleman is alone, he should not be in the company of evil neighbors, so as to be completely pure. When
is stored, it is also necessary to check its appearance frequently. If there is any discoloration, odor, deformation, etc., it cannot be used again. This is essential to protect its quality and effectiveness.