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What are the main uses of 3-aminopyridine-2-formonitrile?
3-Hydroxybutyric acid-2-ethyl ester, that is, beta-hydroxybutyrate ethyl ester, its main uses are as follows:
This is an organic compound that has important uses in many fields. In the field of fragrances, because of its unique odor characteristics, it is often used as a fragrance ingredient, which can give products a different aroma. When blending various floral and fruity fragrances, adding beta-hydroxybutyrate ethyl ester can make the aroma richer, fuller and layered. It is common in the fragrance formulas of daily chemical products such as perfumes, air fresheners, and detergents, which can enhance the olfactory experience of products.
In the field of pharmaceuticals and chemicals, it is also an important intermediate. It can be used to synthesize a variety of drugs, and with its specific chemical structure, it can participate in many drug synthesis reaction steps. For example, in the synthesis path of certain biologically active compounds, beta-hydroxybutyrate ethyl ester, as a starting material or a key intermediate, can be converted into drugs with the effect of treating specific diseases through a series of chemical reactions, which is of great significance to the research and development and production of medicine.
Furthermore, in the field of organic synthesis, it can be used as a basic unit for building complex organic molecular structures. Organic chemists can use the reactivity of their functional groups to combine them with other organic compounds through various organic reactions, such as esterification, condensation, and substitution, to create organic compounds with diverse structures and functions, providing important starting materials for the synthesis of new materials and special chemicals, and promoting the development and innovation of organic synthetic chemistry.
What are the synthesis methods of 3-aminopyridine-2-formonitrile?
There are several methods for the synthesis of 3-aminopyridine-2-carboxylic acid. One is to use pyridine as the initial material and undergo a multi-step transformation. First, pyridine is introduced into the nitro group under specific conditions to form nitropyridine derivatives. This process requires careful control of reaction conditions, such as temperature, reagent ratio, etc., to ensure precise positioning of nitro groups. Then, the nitro group is reduced to amino groups, often with suitable reducing agents, such as iron and hydrochloric acid systems, or catalytic hydrogenation. This step aims to convert the nitro group into the desired amino functional group. Finally, through carboxylation, carboxyl groups are introduced at specific positions in the pyridine ring, resulting in 3-aminopyridine-2-carboxylic acid. < Br >
In addition, there are also other nitrogen-containing heterocyclic compounds as starting materials. For example, the appropriate pyridine analogue is selected, and its structure may already have a skeleton of some target molecules. The purpose of synthesis can also be achieved by modifying and converting the functional groups of the analogue. This path can avoid some more complicated steps in the direct reaction of pyridine, but the selection and synthesis of starting materials are quite demanding.
Another coupling reaction strategy with the help of metal catalysis. The coupling reaction occurs with the halogenate containing the pyridine ring and the reagent containing the amino group and the carboxyl group precursor under the action of the metal catalyst. The key to this method is to select high-efficiency metal catalysts, such as palladium and copper catalysts, and suitable ligands to improve the selectivity and yield of the reaction. At the same time, the alkali, solvent and other factors in the reaction system also have a great impact on the process and results of the reaction, which needs to be carefully considered and optimized.
What are the physical and chemical properties of 3-aminopyridine-2-formonitrile?
3-Hydroxybutyric acid-2-methyl ester is one of the organic compounds. Its physical and chemical properties are unique and are described as follows:
Looking at its physical properties, under room temperature and pressure, 3-hydroxybutyric acid-2-methyl ester is often colorless and transparent to light yellow liquid, like a clear and slightly yellowish brilliance. It has a specific smell. Although it is not rich and pungent, it has a unique smell of a chemical substance, like a unique logo hidden in the molecular structure. And its density is slightly heavier than that of water. When placed in water, it is like a stable stone, slowly settling. At the same time, the substance is soluble in common organic solvents, such as ethanol, ether, etc., just like fish swimming in suitable waters, showing good solubility.
As for its chemical properties, the molecular structure of 3-hydroxybutyric acid-2-methyl ester contains hydroxyl groups and ester groups. Hydroxyl groups have certain activity and can participate in many chemical reactions. When encountering acid, the reverse reaction of esterification reaction can occur, that is, hydrolysis reaction, which is like a molecular level deconstruction and recombination. The existence of ester groups allows them to undergo ester exchange reactions with alcohols, amines and other substances, and constantly change their own forms on the stage of chemical reactions. And under appropriate conditions, oxidation reactions can occur, and hydroxyl groups are oxidized, giving them more chemical changes, just like a flexible and changeable particle in the world of chemical reactions, constantly interpreting the magical chapter of chemical changes.
What is the price range of 3-aminopyridine-2-formonitrile in the market?
In today's market, the quality of acetyl can vary depending on factors such as product quality, source, and supply and demand. Roughly speaking, if acetyl is used for ordinary commercial use, the market price may be between 50 and 100 yuan per catty. However, if it is a high-quality product, it is weighed heavily by workshops and shops, and it may be doubled, from 200 yuan per catty.
If it is a little bit less, it is only used for crude use, and it is only slightly used, or 30 to 50 yuan per catty. And the market is often used. If it is harvested in seasons, more supply is required than demand, and the price will drop; if it is encountered by government orders, the amount will be less, and more supply and less supply will be required, and the price will rise.
As for special-purpose, high-quality acetyl, which is not available in regular stores, it is more expensive, and it is more expensive, and it is not easy to obtain unless it is rich or used. This is generally the case, and the quality of the product needs to be studied, the place of transaction, and the situation of the party.
What are the requirements for the storage conditions of 3-aminopyridine-2-formonitrile?
The storage conditions of 3-aminobutyric acid-2-acetyl have many requirements. These two are special in nature and need to be properly stored in order to maintain their quality and utility.
First, the temperature condition is very critical. It should be stored in a cool place, and the temperature is usually not higher than 25 ° C. Excessive temperature can easily cause its composition to change, or cause chemical reactions to cause it to deteriorate. If it is in a high temperature environment, the activity of 3-aminobutyric acid-2-acetyl molecules is enhanced, which may accelerate decomposition or react with other substances, affecting its purity and efficacy.
Second, the humidity also needs to be strictly controlled. It should be stored in a dry environment, and the humidity is generally controlled at 40% - 60%. Humid environment is easy to make the two absorb moisture, triggering deliquescence. Once deliquescence, not only the appearance changes, but also its chemical properties may be affected, such as hydrolysis reaction, thereby reducing its quality.
Third, light is also an important factor. It needs to be stored away from light because it is sensitive to light. Under light, 3-aminobutyric acid-2-acetyl may undergo photochemical reactions, resulting in structural changes. Therefore, it is usually stored in brown bottles or opaque containers to block light and avoid poor quality caused by light.
Fourth, the storage environment should be kept clean and well ventilated. In an unclean environment, there may be impurities or microorganisms that contaminate 3-aminobutyric acid-2-acetyl. Poor ventilation can cause abnormal local ambient humidity and temperature, which affects its storage stability.
Finally, it is necessary to pay attention to isolation from other substances. Avoid contact with acids, alkalis, strong oxidants and other substances, because of their active chemical properties, contact with them may cause chemical reactions and damage their own structure and properties.