3-Aminopyridine 1-oxide hydrochloride

3-Aminopyridine-1-oxide hydrochloride has a wide range of uses. It is often used as a key intermediate in the field of pharmaceutical synthesis. Due to its unique structure, it can be cleverly combined with other compounds through a series of chemical reactions to construct complex molecular structures with specific pharmacological activities, thus paving the way for the creation of new drugs.
In the field of materials science, it also has important uses. Or it can participate in the preparation process of some functional materials, giving materials such as special electrical, optical or mechanical properties. With its special chemical properties, it plays an indispensable role in the molecular design and performance optimization of materials.
In organic synthetic chemistry, it is an extremely useful reagent. It can be used to promote a variety of organic reactions, such as nucleophilic substitution reactions, oxidation-reduction reactions, etc. With its participation, it can effectively improve the reaction efficiency, increase the yield of target products, and help chemists construct various organic compounds more efficiently.
And in scientific research and exploration, it is also an important research object. Scientists continue to expand their understanding of the reaction laws of organic compounds by exploring their chemical properties and reaction mechanisms, and contribute to the theoretical development of related fields. In short, 3-aminopyridine-1-oxide hydrochloride plays a pivotal role in many fields, promoting the continuous progress of technology and theory in various fields.

3-Aminopyridine-1-oxide hydrochloride is one of the organic compounds. It has unique physical properties, which are described below.
Looking at its properties, at room temperature, it is mostly white to light yellow crystalline powder. This morphology is easy to identify with the naked eye. Its appearance is quite useful in the preliminary identification of substances.
When it comes to solubility, the compound has a certain solubility in water. Water is a common solvent, and many reactions are carried out in water. This solubility allows 3-aminopyridine-1-oxide hydrochloride to participate in many aqueous reactions. At the same time, it also has a certain solubility in some organic solvents, such as ethanol and methanol, which expands its application possibility in different reaction systems.
The melting point is an important physical constant of the substance, and 3-aminopyridine-1-oxide hydrochloride has a specific melting point. Accurate determination of the melting point can assist in judging the purity of the compound. The higher the purity, the closer the melting point is to the theoretical value.
In addition, its stability is also a key physical property. Under normal environmental conditions, if properly stored, it can maintain a relatively stable state. In case of extreme conditions such as high temperature, strong acid, and strong base, its structure may change. This stability consideration is crucial when storing and using the compound. The physical properties of 3-aminopyridine-1-oxide hydrochloride are of great significance in the fields of organic synthesis and drug development, and researchers need to rationally plan experiments and applications according to their characteristics.

The method for preparing 3-aminopyridine-1-oxide hydrochloride is not specified in the ancient book "Tiangong Kaiwu", but the method can be deduced based on current chemical reasons.
First, 3-aminopyridine is often used as the starting material. First, 3-aminopyridine is reacted with an appropriate oxidizing agent to obtain 3-aminopyridine-1-oxide. Common oxidizing agents include hydrogen peroxide. In a suitable solvent, such as an alcohol solvent or a halogenated hydrocarbon solvent, control the temperature and reaction time to make the reaction proceed gently.
When 3-aminopyridine reacts with hydrogen peroxide, the choice of solvent depends on the reaction rate and product purity. If ethanol is used as a solvent, it is heated to a moderate temperature, such as 50-70 ° C, and stirred, and the two react slowly. The reaction process can be monitored by thin-layer chromatography. When the raw material point disappears, the reaction is nearly complete.
Then, the obtained 3-aminopyridine-1-oxide is reacted with hydrogen chloride gas or hydrochloric acid. If hydrogen chloride gas is used, 3-aminopyridine-1-oxide can be placed in a dry reactor, and hydrogen chloride gas is introduced. Under normal temperature or slightly warmed conditions, the two combine to form 3-aminopyridine-1-oxide hydrochloride. If hydrochloric acid is used, the concentration and dosage of hydrochloric acid need to be controlled. After the reaction, the pure 3-aminopyridine-1-oxide hydrochloride can be obtained through evaporation of solvent and crystallization. When crystallizing, controlling the cooling rate and the residual amount of solvent has a great impact on the crystal form and purity of the product.

3-Aminopyridine-1-oxide hydrochloride is a chemical substance that requires special attention during storage and transportation.
When storing, the first environment is dry. This substance is susceptible to moisture. If the environment is humid, or it may cause deliquescence and deterioration, it should be stored in a dry and ventilated place, away from water sources and areas with high humidity.
Temperature is also critical. It should be stored in a cool place to avoid high temperature. Due to high temperature or chemical reactions, the properties of the substance can be changed. Generally speaking, room temperature (about 15-30 ° C) is more suitable, but the specific temperature can be fine-tuned according to the product description.
Furthermore, it needs to be stored separately from other chemicals. 3-Aminopyridine-1-oxide hydrochloride may react with certain substances, such as strong oxidants, strong alkalis, etc., so it is necessary to avoid mixing to prevent danger.
When transporting, the packaging must be stable. Appropriate packaging materials should be selected to ensure that the substance is not damaged and leaked due to vibration or collision during transportation. The packaging should have good sealing to prevent contact with outside air and moisture.
Transportation personnel should also be familiar with the characteristics of this substance. In the event of an unexpected situation such as leakage, correct measures can be taken quickly to prevent the harm from expanding. In conclusion, the storage and transportation of 3-aminopyridine-1-oxide hydrochloride requires careful treatment of the environment, packaging, and personnel handling to ensure the safety and stability of the material.

The market price range of 3-aminopyridine-1-oxide hydrochloride varies due to various factors such as market conditions, quality, and source. In ancient books such as "Tiangong Kaiwu", it is difficult to find a relevant market price for this product, because there is no production and trading of this chemical substance at that time.
Looking at today's chemical market, if it is based on ordinary industrial-grade quality, its price may be between tens and hundreds of yuan per kilogram. However, if it is high purity and special specifications, used in pharmaceutical research and development, high-end chemical experiments, etc., its price will rise sharply, or reach thousands of yuan per kilogram.
The reason for this is that the preparation of high-purity products requires fine craftsmanship and rigorous processes, which greatly increases the cost, so the price is high. And market supply and demand also affect its price. If demand is strong and supply is limited, the price will also increase; on the contrary, if supply exceeds demand, the price may drop. Coupled with different pricing strategies of different suppliers, price fluctuations are also caused. Therefore, in order to know the exact market price, it is necessary to carefully investigate the market dynamics and inquire from relevant chemical raw material suppliers.