3-Aminomethyl-6,7-Dihydro-4H-Isoxazolo[4,5-C]Pyridine-5-Carboxylic Acid Tert-Butyl Ester

This is the problem of 3-aminomethyl-6,7-dihydro-4H-isoxazolo [4,5-c] pyridine-5-carboxylic acid tert-butyl ester. Its chemical structure is similar to that of tert-butyl ester, on the ring of isoxazolo-pyridine, the hydrogen atoms at the 6th and 7th positions are double, and the aminomethyl at the 3rd position is connected, and the carboxyl group at the 5th position is estered with tert-butyl.
Looking at this compound, the ring of isoxazolo-pyridine is its core structure, and the existence of nitrogen and oxygen heteroatoms in the ring gives it unique chemical activities. The dihydrogen state of the 6 and 7 positions causes the ring to have a certain degree of unsaturation, which affects the spatial conformation and electron cloud distribution of the molecule. The aminomethyl group of the 3 position contains amino and methylene groups. The amino group is basic and can participate in many chemical reactions, such as salting with acids or reacting with electrophilic reagents; the methylene is the connecting part, which also plays a role in the spatial arrangement and reactivity of the molecule. The tert-butyl carboxylate of the 5 position has a relatively large tert-butyl ester group, which has a certain spatial barrier and can affect the interaction between molecules. Under certain conditions, the tert-butyl ester group can undergo reactions such as hydrolysis, which makes the carboxyl group free and exhibits the chemical properties of carboxylic acids.
The chemical structure of this compound, the parts are interrelated, and together determine its physical and chemical properties. It is used in the fields of organic synthesis, medicinal chemistry, etc., or has specific uses due to these properties.

3-Aminomethyl-6,7-dihydro-4H-isoxazolo [4,5-c] pyridine-5-carboxylate tert-butyl ester, this compound has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. This structure contains unique nitrogen heterocycles and functional groups, which can be combined with other molecules by organic synthesis to construct complex and diverse drug molecular structures to develop new drugs with specific pharmacological activities.
In the process of drug development, it may be used to construct small molecule inhibitors targeting specific disease targets. For example, for some cancer-related kinases, by rationally designing synthetic routes and converting them into compounds with highly selective inhibitory effects on the kinase, it is expected to provide new drugs for cancer treatment.
In the field of organic synthetic chemistry, it is an extremely useful building block. Because of its functional groups such as aminomethyl and carboxyl tert-butyl esters, it can carry out various reactions such as amidation, esterification, and nucleophilic substitution. With the help of these reactions, chemists can construct a rich and diverse library of organic compounds for screening compounds with potential biological activities or special physical and chemical properties, providing a material basis for research in materials science, medicinal chemistry, and other fields.
In addition, in the study of synthetic methodologies for exploring new heterocyclic compounds, this compound may serve as a model substrate, assisting chemists in developing novel, efficient and green synthesis strategies to enhance the efficiency and selectivity of heterocyclic compound synthesis, and promote the progress and development of organic synthetic chemistry.

Fu 3 - Aminomethyl - 6,7 - Dihydro - 4H - Isoxazolo [4,5 - C] Pyridine - 5 - Carboxylic Acid Tert - Butyl Ester, there are various methods of synthesis. One method can also be started from starting materials containing pyridine and isoxazole structures. First, a suitable functional group is introduced at a certain point on the pyridine ring through a specific reaction, such as a nucleophilic substitution reaction, and a group that can be further converted into aminomethyl groups is introduced.
To obtain aminomethyl, a haloalkyl group can be introduced first, and then treated with ammonia or amine reagents to promote its nucleophilic substitution to form aminomethyl. As for the isoxazole ring, it may need to be constructed in a multi-step reaction during synthesis. The skeleton of the isoxazole ring can be established by condensation reaction of compounds containing carbonyl and hydroxylamine.
In addition, to protect the carboxylic acid as tert-butyl ester, an appropriate tert-butyl alcohol reagent can be selected, and the esterification reaction can be carried out in the presence of acid catalysis or condensation agent. Acid catalysts, such as p-toluenesulfonic acid, condensation agents, such as dicyclohexyl carbodiimide (DCC) and the like.
During the reaction process, pay attention to the conditions of each step of the reaction. Temperature and solvent are all important. The nucleophilic substitution reaction often needs to be in a polar aprotic solvent, such as N, N-dimethylformamide (DMF), to promote the reaction. When constructing the isoxazole ring, the reaction temperature may vary according to the activity of the reactants, and it is possible to be heated at room temperature or at room temperature.
During the esterification reaction, the temperature should be controlled to avoid the side reaction of tert-butyl ester, and the appropriate reaction time should be selected to obtain the best yield. In this way, after careful operation in multiple steps, 3 - Aminomethyl - 6,7 - Dihydro - 4H - Isoxazolo [4,5 - C] Pyridine - 5 - Carboxylic Acid Tert - Butyl Ester can be obtained.

3-Aminomethyl-6,7-dihydro-4H-isoxazolo [4,5-c] pyridine-5-carboxylic acid tert-butyl ester, this is an organic compound. Its physical properties are quite important, and it is related to the application of this compound in many fields.
Looking at its appearance, it is mostly white to off-white solid at room temperature and pressure. This color and morphological characteristics make it easy to distinguish during preliminary identification and observation.
Melting point is also one of the key physical properties. Its melting point is about a specific temperature range, and this value is of great significance for the identification of the purity of this compound and the study of thermal changes. When the temperature rises near the melting point, the compound will gradually melt from a solid state to a liquid state. This transition process is very important for material purification and quality control.
In terms of solubility, it has a certain solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide. This property makes it possible to build a homogeneous reaction system with the help of such solvents in organic synthesis reactions to promote the smooth progress of the reaction. However, in water, its solubility is relatively poor. This feature can be used in the process of separation and purification of compounds to achieve effective separation through the extraction operation of aqueous and organic phases.
In addition, the density of the compound also has a specific value. The physical property of density plays an indispensable role in application scenarios involving mass and volume conversion, such as preparation, measurement of reaction materials, etc. Knowing its density can accurately control the amount of compounds used, and ensure the accuracy and stability of experiments and production processes.
In summary, the physical properties of 3-aminomethyl-6,7-dihydro-4H-isoxazolo [4,5-c] pyridine-5-carboxylate tert-butyl ester, from appearance, melting point, solubility to density, are of great significance for its research, application and related operations.

The price of 3 - Aminomethyl - 6,7 - Dihydro - 4H - Isoxazolo [4,5 - C] Pyridine - 5 - Carboxylic Acid Tert - Butyl Ester in the market is geometric. However, the price of this product is difficult to determine. The price is influenced by many factors, such as the abundance of raw materials, the difficulty of synthesis, the supply and demand of the market, and even the pricing strategy of merchants.
If the raw materials are abundant, the synthesis is easy, and the market demand is stable, the price may be relatively easy; conversely, if the raw materials are scarce, the synthesis is complicated, and the market demand is strong, the price will be high. And different merchants will have different pricing due to different cost considerations and business strategies. There may be those who win by volume, with small profits but quick turnover; there are also those who focus on high-end quality, with high prices and seek big profits.
To determine the exact price of this thing, you need to check the chemical raw material trading platform in detail, consult relevant suppliers, or ask industry insiders to get a more accurate number.