3-Amino-furo[2,3-b]pyridine-2-carboxylicacidethylester

Ethyl 3-amino-furano [2,3-b] pyridine-2-carboxylate is a crucial compound in the field of organic synthesis. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to create various new drugs. Due to its unique chemical structure, it can be modified and derived by a variety of chemical reactions to obtain compounds with specific biological activities.
In the process of pharmaceutical research and development, researchers try to construct complex drug molecular structures, hoping to find innovative drugs with therapeutic effect on specific diseases. For example, for some difficult diseases, such as cancer, neurological diseases, etc., this compound may be chemically modified to have the ability to target specific biological targets, opening up new avenues for drug research and development.
Furthermore, in the field of materials science, it may also have potential applications. In the design and preparation of organic materials, it may endow materials with unique photoelectric properties due to their structural properties, such as the development of Light Emitting Diode, solar cells and other materials, or it can be used to help improve material properties and enhance the efficiency of related devices.
And in the total synthesis of natural products, 3-amino-furano [2,3-b] pyridine-2-carboxylate ethyl ester also plays an important role. When synthesizing complex natural products, it can be used as a key building block to help achieve the precise construction of target molecules, laying the foundation for in-depth research on the biological activity of natural products and the development of related drugs. In short, it has important significance and broad application prospects in many scientific fields.

To prepare 3-amino-furano [2,3-b] pyridine-2-carboxylic acid ethyl ester, it is often done by numerical method.
First, furano [2,3-b] pyridine-2-carboxylic acid ethyl ester is used as the starting material and obtained by amination. First, furano [2,3-b] pyridine-2-carboxylic acid ethyl ester and suitable amination reagents, such as ammonia, amines, etc., are co-prepared under specific reaction conditions. In this case, temperature, pressure, solvent and catalyst are all important factors. The reaction of ammonia gas with furo [2,3-b] pyridine-2-carboxylic acid ethyl ester is catalyzed by ammonia gas as an amino agent in an autoclave under high temperature and pressure with the help of an appropriate metal catalyst. After a series of changes such as nucleophilic substitution, it can reach 3-amino-furo [2,3-b] pyridine-2-carboxylic acid ethyl ester.
Second, it can be prepared by cyclization and condensation of furan and pyridine derivatives containing suitable substituents. For example, furan derivatives and pyridine derivatives with suitable substituents are condensed and cyclized with the help of condensing agents and catalysts. Commonly used condensing agents such as phosphorus oxychloride, carbonyl diimidazole, etc., catalysts such as Lewis acids. In the reaction, according to the activity of the substrate and the reaction process, the reaction temperature, time and material ratio are regulated. After complex cyclization pathways, furano [2,3-b] pyridine ring is formed, and then appropriately modified, amino and ethyl ester groups are introduced to obtain the target product.
Third, biosynthesis is also one of the ways. Use the catalytic activity of specific microorganisms or enzymes to use suitable precursors as raw materials. In the biological system, the catalysis of enzymes has high selectivity and mild reaction conditions. Find a microorganism with the ability to catalyze related reactions, take its enzyme solution after cultivation, put it in a suitable substrate, and put it in a buffer system with suitable temperature and pH value. The enzymatic reaction occurs. After the specific catalysis of the enzyme, the complex transformation is completed to generate 3-amino-furano [2,3-b] pyridine-2-carboxylate ethyl ester. However, biosynthesis methods often need to optimize microorganisms or enzymes to improve yield and activity.

3-Amino-furano [2,3-b] pyridine-2-carboxylic acid ethyl ester, this is an organic compound. Its physical and chemical properties are unique, and they are described as follows:
Looking at its properties, at room temperature, it is mostly white to white solid powder, but its color may change slightly due to purity. The powder is fine in texture, smooth to the touch, and has no special odor.
The melting point is about [specific value] ° C. The melting point is the critical temperature at which the substance changes from solid to liquid, which is crucial for the identification and purification of this compound. At this temperature, the intermolecular force weakens, the lattice structure disintegrates, and then solidifies into a liquid state.
In terms of solubility, this compound exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). This property is attributed to the interaction between its molecular structure and the formation of organic solvent molecules such as hydrogen bonds and van der Waals forces. However, in water, its solubility is very small, and it is difficult to dissolve due to the large proportion of hydrophobic groups in its molecules. The force between water molecules and water molecules is weak, and it is difficult to overcome the hydrogen bond between water molecules.
Stability is also an important property. In normal temperature and pressure, dry environment, this compound is quite stable, and the molecular structure does not change significantly. In case of strong acid, strong alkali, or high temperature and high humidity environment, the stability is greatly affected. Strong acids and bases can cause hydrolysis reactions, and both ester groups and amino groups in the molecule may participate, causing structural changes and forming new compounds. High temperature and high humidity may accelerate its oxidation and affect its chemical activity.
Its spectral properties are also characteristic. In the infrared spectrum, there are characteristic absorption peaks at specific wavenumbers, which characterize the vibration of specific chemical bonds. For example, C = O bonds in ester groups have strong absorption peaks at about 1700 cm, revealing the existence of ester groups. In hydrogen nuclear magnetic resonance spectroscopy, hydrogen atoms in different chemical environments present absorption peaks at different chemical shifts, and the position of the peak, the splitting situation and the integrated area can analyze the number of hydrogen atoms in the molecule and the chemical environment, providing key information for determining the molecular structure.

What you are inquiring about is the price of 3 - Amino - furo [2,3 - b] pyridine - 2 - carboxylic acid ethyl ester in the market. However, the price in the market often changes due to various reasons, such as the abundance of materials, the simplicity of the craftsmanship, the situation of supply and demand, the distance of the region, and the difference in merchants.
If you want to know the exact price, you should follow various paths. First, you can visit the market of chemical raw materials, consult the merchants in person, and the merchants there will often know the current price, and can give different prices according to the quantity. Second, the trading network of Kedeng chemical products, such a platform, gathers merchants, and the price is often listed on it. You can also consult customer service for details of the price. Third, you can ask the experts and experts in the chemical industry, who have been involved in this industry for a long time, are familiar with the market, or can tell you the approximate price.
However, according to my observation, this compound may not be available in the city due to its specialized use. If its preparation requires complicated methods and rare materials, the price will be high; if it is easy to prepare and the materials used are often used, the price may be slightly flat. But in the end, it is difficult to determine its price, and you need to explore it in person to find the true meaning.

3 - Amino - furo [2,3 - b] pyridine - 2 - carboxylic acid ethyl ester is an organic compound, but I have been searching for ancient books, and it is difficult to find the exact manufacturer.
The industry of Guanfu Organic Chemistry is mostly focused on the research and production of such compounds by various fine chemical companies. They may specialize in the creation of heterocyclic compounds, and devote themselves to this field with their profound technical heritage and exquisite craftsmanship.
Today, the global chemical industry is dotted, and there are strong chemical companies in Europe, America and Asia, Japan, South Korea and other places. In the field of organic synthetic chemistry, they may be involved in the production of this compound.
And in the land of China, there is also no shortage of chemical Toshihiko. In the Yangtze River Delta, Pearl River Delta and Bohai Rim, the chemical industry is prosperous. Many fine chemical enterprises have worked hard to cultivate organic synthesis. They may have the ability to produce this compound, but due to the obstruction of information, it has not been widely disseminated.
Or there may be industry-university-research cooperation between universities and scientific research institutes to promote the development of the preparation technology of this compound with academic power, and then give birth to related production entities. If you want to know the exact manufacturer, you need to visit the chemical directory, industry exhibitions, or consult with industry experts to get detailed information.