3-Amino-6-chloropyridine-2-carboxylic acid

3-Amino-6-chloropyridine-2-carboxylic acid, this substance has a wide range of uses. In the field of medicine, it is a key intermediate and can be used to create a variety of drugs. For example, some antibacterial drugs, by modifying and modifying their structure, endow the drug with unique antibacterial activity, which can effectively inhibit the growth and reproduction of specific pathogens, and provide a powerful means for the treatment of infectious diseases. In the field of pesticides, it also plays an important role and can be used as a raw material for the synthesis of new pesticides. The pesticides produced show high selectivity and efficiency to pests, while having little impact on the environment. It is in line with the current concept of green environmental protection and is of great significance to ensure crop yield and quality. In the field of materials science, it can participate in the preparation of functional For example, by polymerizing with other compounds to form materials with special properties, these materials may have unique applications in electronics, optics, etc., such as in the manufacture of new display screens, sensors and other devices, promoting the progress and innovation of materials science and technology. It can be seen that 3-amino-6-chloropyridine-2-carboxylic acids play an indispensable role in many industries and have a profound impact on the development of related fields.

3-Amino-6-chloropyridine-2-carboxylic acid, this is an organic compound. Its physical properties are crucial and are relevant to many applications.
When it comes to appearance, it usually appears as a white to light yellow crystalline powder. This morphological feature is of great significance in practical operation and identification, and its purity and quality can be preliminarily determined by its appearance.
Melting point is also an important characteristic, about 220-225 ° C. The accurate determination of melting point can provide a key basis for the identification and purity evaluation of compounds. The melting point of the compound with different purity may vary, so that its purity can be detected. < Br >
In terms of solubility, it is slightly soluble in water and has limited solubility in common organic solvents such as methanol, ethanol, and dichloromethane. This solubility characteristic must be taken into account when separating and purifying compounds and selecting reaction solvents. Due to its poor solubility, specific solvent systems may be required in some reactions to promote the smooth progress of the reaction.
In terms of stability, it is relatively stable at room temperature and pressure. When encountering strong oxidants, strong acids, and strong bases, or chemical reactions occur, resulting in changes in structure and properties. When storing and using, avoid contact with such substances, and choose suitable storage conditions to ensure its chemical stability.
The physical properties of 3-amino-6-chloropyridine-2-carboxylic acids have far-reaching influence in the fields of chemical industry and medicine. In-depth understanding and precise grasp of them are helpful for related process optimization and product quality improvement.

There are many methods for synthesizing 3-amino-6-chloropyridine-2-carboxylic acids. In the past, there were many ways to do it.
First, it was obtained by halogenation, amination and carboxylation of pyridine derivatives. First, take a suitable pyridine substrate, and under the action of a halogenating agent, such as chlorine gas, sulfoxide chloride, etc., under appropriate conditions, such as specific temperatures and catalysts, connect the chlorine atom to the designated position of the pyridine ring to form a chloropyridine-containing intermediate. Then, with the help of ammonia source, such as liquid ammonia, ammonia water, etc., at high temperature and high pressure or a specific catalyst, ammonia is substituted for a certain group and an amino group is introduced to obtain a pyridine containing amino and chlorine. Finally, carboxylation reagents, such as carbon dioxide, halocarboxylate, etc., are used to connect the carboxyl group to the pyridine ring, and finally 3-amino-6-chloropyridine-2-carboxylic acid.
Second, synthesized by heterocyclic ring construction method. Pyridine ring is formed by cyclization reaction with related raw materials containing nitrogen, chlorine and carboxyl groups. For example, some nitrogen-containing bifunctional compounds and chlorine-containing and carboxyl-based precursors are used to construct a pyridine ring structure under the help of condensation agents and catalysts, in suitable solvents and temperatures, and the target substituent is introduced synchronously to obtain the compound. This approach requires delicate design of the raw material structure and reaction conditions to achieve the expected cyclization and substitution effects.
Third, biosynthetic methods have also been explored. Using the catalytic properties of microorganisms or enzymes, specific substrates are selectively synthesized through enzymatic reactions in vivo. This is an emerging method with the characteristics of green, efficient and excellent selectivity. However, it requires strict biological systems and reaction conditions, and is still in the advanced stage of research. Although each method is different, it is necessary to obtain 3-amino-6-chloropyridine-2-carboxylic acid. The researcher needs to choose the appropriate method according to the actual situation, such as the availability of raw materials, cost, yield and purity requirements.

The price range of 3-amino-6-chloropyridine-2-carboxylic acid in the market is difficult to determine. This is due to the intertwining of many factors, resulting in uncertain price fluctuations.
First, the trend of supply and demand affects the price. If the demand is too much, the demand is too large and the goods are not available, the price will rise; if the supply is too much, the stock and the demand is thin, the price will be depressed. Second, the price of raw materials is also the key. The production of this compound depends on the relevant raw materials. The rise and fall of raw material prices directly affects the cost of this product, which in turn affects the price. Third, the preparation process is complicated and simple. The more complex the process, the more manpower, material and financial resources are required, and the higher the cost, the higher the price; the simpler the process, the lower the cost, the lower the price. Fourth, the market competition situation cannot be ignored. There are many manufacturers, and the competition is fierce, in order to seize the market share, there may be price reductions; there are few manufacturers, with monopoly power, the price may be high.
Looking at past transactions, the price may be between tens of yuan and hundreds of yuan per kilogram. However, this is only an approximate number, not an exact value. To know the current accurate price, you can consult chemical raw material suppliers, chemical trading platforms, or consult with industry insiders at relevant industry exhibitions and seminars to get a real-time price quotation.

3-Amino-6-chloropyridine-2-carboxylic acid is one of the organic compounds and is widely used in medicine, pesticides and other fields. There are many manufacturers and they are scattered all over the world.
In China, there are many manufacturers of this compound. For example, a chemical enterprise in Shandong has exquisite craftsmanship and a large production scale. With advanced equipment and strict quality control, the 3-amino-6-chloropyridine-2-carboxylic acid is of high quality and is not only supplied in the domestic market, but also exported overseas.
Furthermore, there are also manufacturers in Jiangsu that focus on this. The factory focuses on R & D and innovation, continuously optimizes the production process, and strives to improve product quality and production efficiency. The products it produces have a good reputation in the industry and are favored by many downstream enterprises.
There are also many well-known manufacturers overseas. For example, some chemical companies in Europe and the United States have profound technical heritage and unique process and technical advantages in the production of this compound. Its products are famous for their high precision and high purity, and occupy an important position in the international market.
If you want to know the details of the manufacturer, you can obtain more accurate and detailed information through the chemical industry information platform, relevant exhibition materials, or directly consult industry insiders. The chemical industry is developing rapidly, and the dynamics of manufacturers are constantly changing. Real-time tracking is required to keep track of the latest production conditions.