3 Amino 5 Bromopyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

3-amino-5-bromopyridine-2-carboxylic acid

    Specifications

    HS Code

    694289

    Name 3 - amino - 5 - bromopyridine - 2 - carboxylic acid
    Molecular Formula C6H5BrN2O2
    Molar Mass 217.02 g/mol
    Appearance Solid (usually powder)
    Melting Point Specific value needs further experimental determination
    Boiling Point Specific value needs further experimental determination
    Solubility In Water Low solubility, sparingly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka Specific pKa values for amino and carboxylic acid groups need experimental determination
    Stability Stable under normal conditions, but sensitive to strong acids, bases and oxidizing agents
    Odor Odorless or very faint odor

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    General Information
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    Frequently Asked Questions

    As a leading 3-amino-5-bromopyridine-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-amino-5-bromopyridine-2-carboxylic acid?
    3-Amino-5-bromopyridine-2-carboxylic acid has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate in organic synthesis. In the process of drug development, it can be used as a starting material to build complex active molecules through a series of chemical reactions, laying the foundation for the creation of new drugs. For example, for specific disease targets, chemists carefully design and synthesize drug molecules that fit with them, and 3-amino-5-bromopyridine-2-carboxylic acids play an important role in the starting structure.
    In the field of materials science, it also has unique uses. It can participate in the preparation of functional materials, such as materials with special optical and electrical properties. By modifying and modifying its chemical structure, the properties of the material can be adjusted to meet the needs of different fields such as photoelectric display and sensors. For example, when developing new photoelectric materials, its structural characteristics are used to endow the materials with unique light absorption and emission properties and improve the efficiency of photoelectric devices.
    In addition, in organic synthesis chemistry, it is used as an important building block to construct diverse pyridine derivatives. According to the principles and strategies of organic synthesis, chemists select suitable reaction conditions and reagents to promote their reaction with other compounds, synthesize organic compounds with novel structures and specific functions, enrich the library of organic compounds, and open up a broad space for chemical research and application.
    What are the synthetic methods of 3-amino-5-bromopyridine-2-carboxylic acid?
    There are many methods for the synthesis of 3-amino-5-bromopyridine-2-carboxylic acid. The method of the past, or starting from the pyridine derivative. First, you can take the appropriate pyridine first, and introduce the bromine atom at the 5th position through the halogenation reaction. This halogenation method often uses bromine and an appropriate catalyst in a suitable solvent to control the temperature and make the bromine site-selective substitution. Then, the amination reaction is carried out, and the amino group is introduced at the 3rd position. The amination can be reacted with the pyridine derivative under specific conditions by means of a reaction such as nucleophilic substitution. Or the carboxyl group is introduced at the 2nd position first, and the method of introducing the carboxyl group can be obtained by hydrolysis of the corresponding ester or by hydrolysis of the cyanide group. Ester hydrolysis requires a suitable acid-base as a catalyst, and cyano hydrolysis also requires specific reaction conditions.
    Another approach is to synthesize heterocyclic rings. Pyridine rings can be constructed by multi-step reactions, and the positions of bromine, amino and carboxyl groups can be planned at the same time. For example, using small molecules containing nitrogen and carbon as raw materials, through a series of reactions such as condensation and cyclization, the pyridine skeleton is gradually built, and each substituent is precisely introduced in appropriate steps.
    In addition, in modern organic synthesis, there are also methods of catalysis with the help of transition metals. Using the unique activity and selectivity of transition metal catalysts, the reaction of bromination, amination and carboxylation can be promoted to efficiently synthesize the target product. These methods have their own advantages and disadvantages, and they need to be selected according to various factors such as the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
    What are the physical properties of 3-amino-5-bromopyridine-2-carboxylic acid?
    3-Amino-5-bromopyridine-2-carboxylic acid is also an organic compound. Its physical properties are unique and of important research value.
    Looking at its properties, under normal temperature and pressure, it mostly takes the form of a solid. Its melting point is one of the keys to the properties of the substance. It has a specific value due to factors such as intermolecular forces, but the specific melting point will change due to conditions such as purity.
    In terms of solubility, it varies in organic solvents. In polar organic solvents, such as methanol and ethanol, it may have a certain solubility. Its molecular structure contains polar groups, and it can form intermolecular forces with polar solvents, such as hydrogen bonds, to promote dissolution. In non-polar organic solvents, such as n-hexane, the solubility may be very small, because of the weak interaction between the molecules of the non-polar solvent.
    In addition, this compound has certain stability, but under specific conditions, it will also change. In case of high temperature, strong acid, strong base, etc., the molecular structure may be damaged, triggering a chemical reaction. Its stability is related to the chemical bond energy and spatial structure of the molecule.
    The physical properties of 3-amino-5-bromopyridine-2-carboxylic acid are influenced by various factors such as molecular structure, chemical bond and external conditions, which is of great significance for its application in organic synthesis, drug development and other fields.
    What is the market price of 3-amino-5-bromopyridine-2-carboxylic acid?
    3-Amino-5-bromopyridine-2-carboxylic acid, the price of this product in the market is difficult to say directly. The price of this product often changes for many reasons, just like the vagaries of the situation.
    The first to bear the brunt is the level of its purity. If the purity of this product is high, it is almost flawless, like a well-crafted jade, its price must be high; if the purity is slightly inferior, it seems that the jade contains minor flaws, the price will also drop.
    Furthermore, the scale of production is also critical. If large-scale production is like a torrential river, there will be a steady stream of water. Due to the benefits of scale, the cost will be reduced, and the price in the market may become more affordable. If it is produced in small quantities, it is like a trickle, and the cost rises, the price will remain high.
    The balance between supply and demand also affects the price. If there are many people in the market who want it, but there are few people who supply it, like the clouds in the hope of a drought, the price will rise; on the contrary, if the supply is full and the demand is small, the price will fall.
    In addition, the cost of raw materials and the complexity of the preparation process are closely related to the price. If the raw materials are not easy to obtain, or the preparation process is extremely complicated, such as the difficulty of climbing the road, the price will also be affected by it and fluctuate. Therefore, in order to know the exact market price of 3-amino-5-bromopyridine-2-carboxylic acid, it is necessary to carefully observe the current market conditions and comprehensively consider the above factors to obtain a more accurate valuation.
    Where is 3-amino-5-bromopyridine-2-carboxylic acid used?
    3-Amino-5-bromopyridine-2-carboxylic acid, this compound is useful in medicine, materials and other fields.
    In the field of medicine, it is an important organic synthesis intermediate. Through chemical reactions, it can be converted into compounds with specific biological activities. For example, after modification, drugs with antibacterial effects may be obtained. In the process of bacterial cell wall synthesis, such derivatives may play a role, inhibiting bacterial growth by interfering with key metabolic links of bacteria, providing a new way for the development of antibacterial drugs. Or anticancer drugs can be constructed through specific reactions. Some cancer cells require specific biomolecules for proliferation, and the compounds derived from this compound may block the generation pathway of these biomolecules and inhibit cancer cell growth. < Br >
    In the field of materials, it also has its uses. Due to its unique molecular structure, it can be used to prepare functional polymer materials. After polymerization, it is introduced into the polymer skeleton to give the material special properties. For example, it can prepare materials that selectively adsorb specific substances. In wastewater treatment, it exhibits high adsorption capacity for certain heavy metal ions or organic pollutants, helping to purify water quality. Or it can be used to prepare optical materials. Its structure may enable the material to have special optical properties, such as fluorescence properties. It can be used as a fluorescent probe in the field of optical sensors to detect the presence and concentration of specific substances. 3-Amino-5-bromopyridine-2-carboxylic acids have broad prospects in the fields of medicine and materials, and can provide effective ways to solve many practical problems and promote the development of related fields.