3 Amino 4 Bromo 2 6 Dichloropyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Amino-4-bromo-2,6-dichloropyridine

    Specifications

    HS Code

    975738

    Chemical Formula C5H3BrCl2N2O
    Molecular Weight 241.90
    Appearance Solid (predicted)
    Boiling Point 352.7°C at 760 mmHg (predicted)
    Melting Point 175 - 177°C
    Density 1.954 g/cm³ (predicted)
    Solubility In Water Insoluble (predicted)
    Logp 2.44 (predicted)
    Flash Point 167.1°C (predicted)
    Pka 12.14±0.40 (predicted)

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    General Information
    Where to Buy 3-Amino-4-bromo-2,6-dichloropyridine in China?
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    Frequently Asked Questions

    As a leading 3-Amino-4-bromo-2,6-dichloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3-Amino-4-bromo-2,6-dichloropyridine?
    3-Amino-4-bromo-2,6-dichloropyridine, this is an organic compound. Its chemical properties are unique and of great research value.
    Looking at its structure, amino, bromine and chlorine atoms are cleverly connected to the pyridine ring. Amino is a donator group, which can enhance the electron cloud density of the pyridine ring, which is crucial in electrophilic substitution reactions. Because of its donator properties, it can make the pyridine ring more attractive to electrophilic reagents and promote the reaction to occur more easily.
    Bromine and chlorine atoms are electron-withdrawing groups, which can reduce the electron cloud density of the pyridine ring. In many reactions, this electron-withdrawing effect affects the reaction check point and reactivity. For example, in nucleophilic substitution reactions, the positions of bromine and chlorine atoms are more susceptible to nucleophilic attack due to the decrease in electron cloud density.
    In terms of acidity and alkalinity, the presence of amino groups imparts a certain alkalinity to the compound. The nitrogen atom in the amino group contains lone pairs of electrons, which can accept protons and exhibit alkaline characteristics.
    In chemical reactions, 3-amino-4-bromo-2,6-dichloropyridine can participate in a variety of reaction types. For example, in the electrophilic substitution reaction, the electron effect of the amino group will guide the electrophilic reagent to mainly attack the specific position on the pyridine ring; in the nucleophilic substitution reaction, the bromine and chlorine atoms provide a good reaction check point for the nucleophilic reagent. This compound may also participate in condensation reactions, etc. In the field of organic synthesis, with these reaction characteristics, it may be used to construct more complex organic molecular structures, and has potential applications in many fields such as medicinal chemistry and materials science.
    What are the main uses of 3-Amino-4-bromo-2,6-dichloropyridine?
    3-Amino-4-bromo-2,6-dichloropyridine is an important compound in the field of organic synthesis, with a wide range of uses and outstanding performance in various industries.
    First, in the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of new drugs. Due to its special chemical structure, it can impart specific biological activities and pharmacological properties to drug molecules. By means of organic synthesis, it can be ingeniously introduced into the molecular structure of drugs, and then developed into highly effective therapeutic drugs for specific diseases. For example, in the research and development process of anti-tumor drugs, by modifying and optimizing their structures, it is expected to create new drugs with highly selective killing effects on tumor cells, which will contribute to the solution of cancer problems.
    Second, in the field of pesticide chemistry, 3-amino-4-bromo-2,6-dichloropyridine also plays a pivotal role. It can be used as an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. After reasonable chemical transformation, pesticide products with excellent insecticidal, bactericidal or herbicidal properties can be prepared. Such pesticides can not only effectively control crop diseases and pests, ensure food yield and quality, but also have relatively little harm to the environment due to their low toxicity, which is in line with the current needs of green agriculture development.
    Furthermore, in the field of materials science, the compound has made a name for itself in the synthesis of organic optoelectronic materials due to its unique electronic structure and chemical properties. Through careful design and synthesis, it can be applied to organic light emitting diodes (OLEDs), organic solar cells and other fields. In OLEDs, it may be used as a key component of luminescent materials to improve the luminous efficiency and stability of devices; in organic solar cells, it may improve the photoelectric conversion efficiency of batteries and promote the progress of renewable energy technologies.
    In conclusion, 3-amino-4-bromo-2,6-dichloropyridine has shown great application potential in many fields such as medicine, pesticides and materials science due to its diverse uses, and is of great significance for promoting the development of related industries.
    What are the synthesis methods of 3-Amino-4-bromo-2,6-dichloropyridine?
    The synthesis method of 3-amino-4-bromo-2,6-dichloropyridine has been known for a long time, and there are many exquisite methods.
    First, it can be started by a specific pyridine derivative. First, a suitable halogenation reagent is used to halogenate a specific position on the pyridine ring. If a brominating agent is used, under appropriate reaction conditions, bromine atoms are introduced at the 4th position of the pyridine ring; then a chlorination reagent is used to introduce chlorine atoms at the 2nd and 6th positions. This process requires precise control of the reaction temperature, time and reagent dosage to make the halogenation reaction proceed as expected.
    Second, amino-containing pyridine compounds are also used as raw materials. The amino group is first protected to prevent it from being affected in subsequent reactions. Then bromination and chlorination are carried out in sequence. After the halogenation is completed, the amino protecting group is carefully removed to obtain the target product. In this approach, the selection of protecting groups and the optimization of deprotection conditions are crucial.
    Third, there is a strategy to achieve this by constructing a pyridine ring. Using a suitable small molecule compound containing nitrogen and halogen atoms as the starting material, the pyridine ring structure is constructed by cyclization reaction, and the introduction of bromine and chlorine atoms at specific positions is achieved. This cyclization reaction often requires catalyst assistance, and the reaction conditions need to be carefully adjusted to ensure the selectivity and yield of the product.
    All this synthesis method requires chemists to use exquisite skills and rigorous attitude, carefully consider the reaction conditions, and carefully handle the intermediate products in order to effectively synthesize 3-amino-4-bromo-2,6-dichloropyridine, providing a solid material foundation for research and application in related fields.
    What is the price range of 3-Amino-4-bromo-2,6-dichloropyridine in the market?
    The price range of 3-amino-4-bromo-2,6-dichloropyridine in the market is difficult to determine. The price often varies due to a variety of factors, such as supply and demand, preparation methods, quality, purchase quantity, and even fluctuations in market conditions.
    In the past, the price of chemical materials relied on business negotiations and market research to clarify. If the preparation of this product is difficult, the raw materials are rare, and the demand is ardent, the price will be high. On the contrary, if the preparation method is simple, the raw materials are abundant, and the demand is small, the price may be easy.
    Looking at "Tiangong Kaiwu", although it is detailed in all kinds of technological creations, at that time, the chemical research was not as advanced as it is today, and there was no such fine compound, so it was difficult to find a price.
    There are three possible things to know about its price today. First, consult the suppliers of chemical raw materials, who often quote according to real-time market conditions and purchase quantities; second, visit the chemical product trading platform, which often collects quotations from many companies and can be compared; third, refer to academic literature, industry reports, or get a general price trend. However, it must always be understood that the price of this compound is not static and must change with various factors.
    What are the storage conditions for 3-Amino-4-bromo-2,6-dichloropyridine?
    3-Amino-4-bromo-2,6-dichloropyridine is an organic compound, and its storage conditions are very critical. This substance should be placed in a cool, dry and well-ventilated place. Because of the cool place, it can avoid high temperature and cause its properties to change. In a dry environment, it can avoid water vapor intrusion, deliquescence and other conditions, which can damage its purity. Well ventilated, it can prevent the accumulation of harmful gases and affect its quality.
    And it needs to be kept away from fire and heat sources, both of which are at risk of triggering chemical reactions, or causing their decomposition, combustion, and even explosion. Furthermore, it should be stored separately from oxidants, acids, and bases, and should not be mixed. Because the oxidizing agent has strong oxidizing properties, or an oxidation reaction occurs with the compound; acids and bases are chemically active and may also react with them to deteriorate the substance.
    When storing, there should be suitable materials to contain the leakage. If it leaks accidentally, it can be collected and processed in time to avoid polluting the environment and preventing harm to personnel. The packaging should be well sealed to maintain its stability and prevent external factors from interfering. Following these storage conditions can ensure the quality and safety of 3-amino-4-bromo-2,6-dichloropyridine.