3 Amino 2 Methoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Amino-2-methoxypyridine

    Specifications

    HS Code

    110076

    Name 3-Amino-2-methoxypyridine
    Molecular Formula C6H8N2O
    Molecular Weight 124.14 g/mol
    Appearance Solid (usually)
    Melting Point 64 - 66 °C
    Boiling Point 261 - 263 °C
    Density 1.147 g/cm³ (estimated)
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Pka Value Around 4.85 (protonated form)
    Odor Typical amine - like odor
    Flash Point 111 °C

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    General Information
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    Frequently Asked Questions

    As a leading 3-Amino-2-methoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-amino-2-methoxypyridine?
    3-Hydroxy-2-methylhydroxybenzoquinone has many main uses.
    In the field of medicine, it is quite effective. It has certain antioxidant properties and can scavenge free radicals generated by the body. Free radicals are the source of cell damage, aging and various diseases. Therefore, 3-hydroxy-2-methylhydroxybenzoquinone can protect cells from free radical damage by antioxidant, and is beneficial in delaying aging and preventing chronic diseases such as cardiovascular diseases and neurodegenerative diseases. And studies have shown that it may have antibacterial and anti-inflammatory properties, which can deal with some bacterial infections and inflammation-related diseases, providing a new path for pharmaceutical research and development. < Br >
    In the chemical industry, it also has its uses. Due to its special chemical structure, it can be used as a raw material or intermediate for the synthesis of many fine chemicals. After chemical transformation, polymer materials and dyes with specific properties can be prepared. For example, other functional groups can be introduced through specific reactions to improve the properties of materials, such as improving the stability and dyeability of materials, and expanding the variety and application of chemical products.
    In the biological field, it may regulate the metabolic process in organisms. It can participate in the signal transduction pathway in cells, affect the expression of related genes and the activity of proteins, and then regulate the growth, differentiation and apoptosis of cells. This is of great significance for in-depth exploration of physiological and pathological mechanisms in organisms, and may open up new ideas for biomedical research, and help innovation in disease diagnosis and treatment strategies.
    In short, 3-hydroxy-2-methylhydroxybenzoquinone has important uses in medicine, chemical industry, biology and other fields, providing broad prospects for scientific research and industrial development.
    What are the physical properties of 3-amino-2-methoxypyridine?
    3-Hydroxy-2-methylhydroxyanisole is one of the organic compounds. Its physical properties are unique, let me describe them in detail for you.
    Looking at its appearance, under normal temperature and pressure, it is mostly white to light yellow crystalline powder with fine texture, which is easy to observe and use.
    As for its melting point, it is about 57 ° C - 65 ° C. Such a melting point range allows the substance to be converted from solid to liquid within a specific temperature range, which is of great significance in many chemical operations and experimental processes. For example, in some scenarios where it needs to be melted to participate in the reaction, the temperature can be precisely controlled to the vicinity of the melting point to achieve the goal. The boiling point of
    is usually around 295 ° C. This boiling point value indicates that a higher temperature is required to make it change from liquid to gaseous. This characteristic is in the process of separation and purification of substances. If distillation and other means are used, the temperature needs to be raised to this boiling point before the substance can be vaporized and separated from other components.
    Solubility is also one of its important physical properties. This substance is soluble in organic solvents such as ethanol, ether, and acetone. In ethanol, it can be dispersed more uniformly to form a uniform and stable solution system. However, its solubility in water is relatively low. This solubility characteristic determines the existence state and reactivity of the substance under different solvent environments. In the field of organic synthesis, selecting a suitable organic solvent to dissolve 3-hydroxy-2-methylhydroxyanisole plays a key role in promoting the smooth progress of the reaction.
    In addition, the substance has a certain odor, but it is not a pungent and unpleasant smell, but a slightly mild special smell. This odor characteristic also needs to be considered in some product applications that require odor.
    In summary, the physical properties of 3-hydroxy-2-methylhydroxyanisole, from appearance, melting point, boiling point, solubility to odor, have their own unique characteristics, which together shape its unique position and application value in the chemical field.
    What are the chemical properties of 3-amino-2-methoxypyridine?
    3-Hydroxy-2-methylhydroxybenzaldehyde is one of the organic compounds. It has the characteristics of both hydroxyl and aldehyde groups, is active and changeable, and shows unique ability in many chemical reactions.
    The aldehyde group has the property of reducing, and can be oxidized by weak oxidants such as Torun reagent and Feilin reagent to form a carboxyl group. In case of Torun reagent, the aldehyde group is oxidized to carboxylate, and silver is precipitated at the same time, which is like a silver mirror. This is one of the characteristic reactions of aldehyde group to test the existence of aldehyde.
    Its hydroxyl group is not idle, and it is weakly acidic. Although the acidity is inferior to that of common inorganic acids, it can react with bases to form corresponding salts. And the hydrogen atoms in the adjacent and para-hydroxyl groups are greatly increased in activity due to the conjugation effect of aldehyde and hydroxyl groups, and are prone to substitution reactions. For example, when it encounters bromine water, the hydrogen in the adjacent and para-hydroxyl groups can be replaced by bromine atoms to form bromogenates.
    And because it has both hydroxyl and aldehyde groups in the molecule, it can undergo intramolecular or intermolecular condensation reactions. Under appropriate conditions, the intramolecular hydroxyl and aldehyde groups are condensed to form a cyclic semi-acetal structure; if it is an intermolecular reaction, a larger condensation product can be formed.
    This compound has a wide range of uses in the field of organic synthesis and can be used as an intermediate to construct more complex organic molecules through many reaction paths. Due to its unique chemical properties, it plays an important role in pharmaceutical synthesis, fragrance preparation, and other industries, and is a key raw material for many scientific research and industrial production.
    What are the synthesis methods of 3-amino-2-methoxypyridine?
    To prepare 3-amino-2-methylaminopyridine, there are many methods.
    First, the corresponding pyridine derivative can be obtained by substitution reaction. First, find a pyridine substrate containing suitable substituents, so that halogen atoms or other easily exiting groups occupy the place where the amino group is to be introduced. Then, choose a nucleophilic reagent, such as ammonia or methylamine, under suitable conditions, the nucleophilic attacks the substrate, the halogen atom leaves, and the amino or methylamino groups are introduced to obtain the target product. This process requires careful regulation of reaction temperature, time and reagent ratio to improve yield and selectivity. If the halogenated pyridine is used as the starting material, in an appropriate solvent, the reaction with excess ammonia under heating and pressure may achieve the substitution of amino groups; the methylamino group can be introduced through similar steps.
    Second, the pyridine ring can also be constructed by cyclization reaction. First, small molecular compounds containing nitrogen and carbon are used as raw materials, such as nitroenamines and dicarbonyl compounds. The two are condensed and cyclized to form a pyridine ring structure. During the reaction design, the substituent positions are cleverly arranged so that the possibility of introducing amino and methylamino groups is reserved at the target check point after cyclization. After cyclization, amino and methylamino groups are introduced at the corresponding positions through specific reactions, such as reduced amination.
    Third, catalytic hydrogenation reduction is also a feasible way. If the starting material is a pyridine derivative containing nitro or other groups that can be reduced to amino groups, catalytic hydrogenation can be used. With a suitable catalyst, such as palladium carbon, in a hydrogen atmosphere, nitro and other groups can be reduced to amino groups. If the substrate has nitro and groups that can be converted into methylamino groups, the synthesis of 3-amino-2-methylamino pyridine can be achieved by controlling the reaction conditions. However, catalytic hydrogenation requires attention to the safety of the reaction and strict control of parameters such as hydrogen pressure and reaction temperature.
    What are the precautions for 3-amino-2-methoxypyridine in storage and transportation?
    3-Amino-2-methylaminopyridine is a chemical substance. Care must be taken in storage and transportation. The following points must be kept in mind.
    The choice of the first storage environment. It needs to be stored in a cool, dry and well-ventilated place. Because if the substance is heated or damp, it is very likely to cause a chemical reaction and cause its properties to change. It must not be placed in direct sunlight, nor should it be in contact with humid environments such as water sources and steam. For example, the location of the warehouse should be away from water sources and high temperature areas, and there should be good ventilation facilities to ensure air circulation and avoid the accumulation of harmful gases.
    The choice of times and storage containers. It must be stored in a container with good sealing performance. In this way, it can not only prevent its volatilization, but also avoid reaction with the air. Generally speaking, it is advisable to use sealed containers made of glass, plastic and other materials, and the material of the container must not react chemically with the substance. For example, special glass bottles are selected and equipped with tightly sealed caps to ensure the safe storage of the substance.
    Furthermore, the transportation process should not be underestimated. During transportation, ensure that the packaging is complete and firm to prevent the container from being damaged or leaked during transportation. At the same time, it should be classified as a specific hazardous chemical for transportation in accordance with relevant regulations. The transportation vehicle should be equipped with corresponding protective equipment and emergency treatment tools, and the transportation personnel should also undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. If there is an emergency during transportation, it can be dealt with in time and properly.
    In addition, whether it is storage or transportation, it is necessary to strictly follow relevant regulations and standards, and make detailed records, such as storage time, location, quantity, transportation route, time and other information, for follow-up inquiry and traceability. And it is strictly forbidden to mix with oxidants, acids and other substances, because it may have violent reactions, resulting in serious consequences. In short, only by comprehensively doing all the precautions can we ensure the safety and stability of 3-amino-2-methylaminopyridine during storage and transportation.