3-Amino-2-hydroxypyridine

3-Amino-2-hydroxypyridine, this substance has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. For example, some antibacterial drugs, with their unique chemical structure, can effectively inhibit the growth and reproduction of pathogens, which is of great significance for resisting infectious diseases. In the creation of pesticides, it is also a commonly used raw material, which can help to develop efficient and low-toxicity pesticides, providing a strong guarantee for agricultural pest control.
In the field of materials science, its role should not be underestimated. It can participate in the preparation of polymer materials with unique functions, endowing materials with special optical and electrical properties, and has potential applications in frontier fields such as optoelectronic materials and sensors. Because it contains specific reactive groups, it can chemically react with other substances to build a material system with specific functions.
In addition, in the field of organic synthesis chemistry, 3-amino-2-hydroxypyridine is often used as a building block for organic synthesis. With its structural characteristics, it can construct complex and diverse organic compounds through various chemical reactions, providing rich raw materials and diverse paths for the development of organic synthesis chemistry. In short, 3-amino-2-hydroxypyridine plays an important role in many fields, promoting the continuous progress and development of related industries.

3-Amino-2-hydroxypyridine is a kind of organic compound. Its physical properties are particularly important and are related to many chemical applications.
Looking at its properties, it is mostly solid at room temperature. The color of this compound is either white to light yellow, and its appearance is carefully observed, or it is a crystalline powder with fine texture.
When it comes to melting point, the melting point of this substance is about within a certain range. The specific value often varies slightly due to experimental conditions and sample purity, but it is roughly in a certain range. This melting point characteristic is useful in the identification and purification process.
Solubility is also a key physical property. 3-Amino-2-hydroxypyridine has a certain solubility in water, but it is not very soluble. Because of its molecular structure, there are both hydrophilic amino and hydroxyl groups, as well as pyridine rings with certain hydrophobicity, it has better solubility in polar solvents such as methanol and ethanol, and can be better dispersed and dissolved. In organic solvents such as ether and benzene, the solubility is relatively weak.
In addition, its density also has a specific value. Although it is not the focus of daily attention, density data is also indispensable in accurate stoichiometry and reaction system design, which is related to the ratio of reactive materials and the regulation of the physical state of the system.
Its volatility is weak, and it is not easy to evaporate into the air at room temperature and pressure. This characteristic makes storage and operation relatively convenient, reducing losses and potential safety risks caused by volatilization.
In short, the physical properties of 3-amino-2-hydroxypyridine are diverse, including melting point, solubility, density and volatility. In chemical synthesis, analytical testing and related industrial applications, it is a key consideration, which profoundly affects its use and effect.

3-Amino-2-hydroxypyridine is one of the organic compounds. Its properties are unique and weakly basic, and the cover is also because its amino group can bind protons. And this compound can form intramolecular or intermolecular hydrogen bonds because it contains hydroxyl groups and amino groups, which has a great influence on its physical and chemical properties.
In terms of solubility, because it has both polar groups, it can show a certain solubility in water and some polar organic solvents. When heated, 3-amino-2-hydroxypyridine may appear to decompose, which is related to the stability of its molecular structure.
In terms of chemical activity, amino groups can cause nucleophilic substitution reactions. If suitable electrophilic reagents are encountered, amino groups can be used as nucleophilic centers to participate in the reaction. And hydroxyl groups are not much better, and can participate in reactions such as esterification. Its pyridine ring is also aromatic and can undergo aromatic electrophilic substitution reactions, but the reactivity is closely related to the localization effect of the substituent group.
Furthermore, 3-amino-2-hydroxypyridine may have tautomerism under specific conditions, which is due to the interaction between hydroxyl groups and pyridine ring nitrogen atoms. The existence of tautomers also affects its overall chemical properties.
In summary, 3-amino-2-hydroxypyridine has rich and diverse chemical properties, which are determined by its unique molecular structure. It has important application value and research significance in organic synthesis and related fields.

In the past, there were many ways to synthesize 3-amino-2-hydroxypyridine. The first is to introduce a halogen atom into the pyridine ring by halogenation. After that, the halogenated pyridine is reacted with an amino-containing reagent, such as ammonia or amine, under suitable conditions to obtain an amino-substituted pyridine derivative. Then, by appropriate oxidation or other conversion means, the hydroxyl group is introduced into the ortho position to form 3-amino-2-hydroxypyridine.
Second, it can be modified from natural products or known compounds containing pyridine rings through multiple chemical reactions. For example, the functional groups of the raw pyridine derivatives are first protected to prevent them from being unnecessarily affected in subsequent reactions. Then, by means of nucleophilic substitution, electrophilic substitution and other reactions, the desired positions of the amino and hydroxyl groups in the pyridine ring are gradually constructed. After the deprotection step, the final target product is obtained.
Or, the reaction strategy of metal catalysis is adopted. For example, a transition metal catalyst is used to catalyze the reaction of the substrate containing the pyridine backbone with a suitable nucleophilic reagent to precisely introduce the amino and hydroxyl groups. In this process, the choice of metal catalyst, the reaction solvent, temperature, and the type and amount of base all have a significant impact on the yield and selectivity of the reaction. The ideal synthesis effect can be achieved only after careful optimization of conditions. < Br >
The methods for synthesizing 3-amino-2-hydroxypyridine have their own advantages and disadvantages, and must be carefully selected according to factors such as actual demand, availability of raw materials, and operability of reaction conditions.

3-Amino-2-hydroxypyridine, the price in the market, it is difficult to determine. The price of the cover often changes for many reasons, such as the supply and demand of materials, the technology of production, and the state of the market.
Looking at the past market conditions, its price may change significantly. If the supply of materials is sufficient, and the method of production is good, resulting in abundant production, the price may decline; on the contrary, if the material is thin, or difficult to make, resulting in less production, the price will rise.
In the chemical market, its price often changes with the upstream and downstream market conditions. If the price of the required raw materials rises, the cost of the system increases, and the price also rises accordingly; if the downstream demand decreases, the supply exceeds the demand, and the price is easy to fall.
Although it is difficult to determine the price of the domain, but looking at the history of past transactions and market analysis, probably if the supply is stable and flat, the price may be in the domain of hundreds of yuan per kilogram; if the market changes, such as the shortage of raw materials, or the sudden increase in demand, the price may be doubled or even higher; conversely, if the supply is too much and the demand is too great, the price may fall to a lower position.
In short, if you want to know the actual price, you should carefully observe the current market dynamics, consult the industry's business, or observe professional market analysis platforms, in order to obtain a near-real price.