3-Amino-2-fluoro-4-methylpyridine

3-Amino-2-fluoro-4-methylpyridine is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of drugs in the field of medicinal chemistry. Due to the special structure of this compound, it contains amino groups, fluorine atoms and methyl groups, giving it unique chemical and biological activities.
In drug development, this compound can be chemically modified to construct molecular structures with specific pharmacological activities. For example, by linking with other active groups, or changing the position and type of their substituents, new drug molecules targeting specific disease targets can be created, which are expected to be used in the synthesis of antibacterial, anti-inflammatory, anti-tumor and many other drugs.
In the field of materials science, 3-amino-2-fluoro-4-methylpyridine is also used. Because of its chemical structure, it can participate in specific chemical reactions, or can be used as a raw material for the synthesis of functional materials, used to prepare materials with special optical, electrical or mechanical properties, such as materials used in organic Light Emitting Diode (OLED) materials, or materials with specific adsorption and separation functions.
In addition, in the field of organic synthetic chemistry, it is an important building block. Chemists can regulate the reactivity of amino, fluorine atoms and methyl groups to carry out various organic reactions, such as nucleophilic substitution, electrophilic substitution, coupling reaction, etc., to synthesize more complex and diverse organic compounds, enrich the organic compound library, and lay the foundation for further scientific research and industrial applications. In short, 3-amino-2-fluoro-4-methyl pyridine has important uses in many fields such as medicine, materials and organic synthesis due to its unique structure.

3-Amino-2-fluoro-4-methylpyridine is one of the organic compounds. It has various physical properties, which are listed below.
When it comes to appearance, 3-amino-2-fluoro-4-methylpyridine is often white to light yellow crystalline powder. This color state is easy to identify, and in practical applications and research, it can be one of the aids in identifying the substance.
As for the melting point, it is about a specific temperature range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 3-amino-2-fluoro-4-methylpyridine is an important indicator of its physical state changes at different temperatures. If the temperature rises above the melting point, the substance will melt into a liquid state, which has a great influence on processes such as separation, purification and certain chemical reactions.
In terms of solubility, it exhibits a certain solubility in some organic solvents. For example, in common organic solvents such as ethanol and dichloromethane, it can be moderately dissolved. This solubility facilitates its application as a reactant or intermediate in organic synthesis reactions. Because it can be dissolved in a specific solvent, the contact between the molecules of the reactants is more sufficient, which is conducive to the progress of the reaction, and facilitates the separation and purification of the products after the reaction.
Furthermore, the compound has a certain vapor pressure. Vapor pressure characterizes the tendency of a substance to evaporate from a liquid or solid state to a gaseous state. Although 3-amino-2-fluoro-4-methylpyridine is not very volatile, its vapor pressure under specific conditions cannot be ignored. During storage and use, the potential impact of its vapor pressure on the environment and operation should be considered to ensure safe and effective handling.
In summary, the physical properties of 3-amino-2-fluoro-4-methylpyridine, such as appearance, melting point, solubility, and vapor pressure, are of great significance in chemical research, industrial production, and related fields, laying the foundation for the rational use and in-depth investigation of this compound.

The synthesis method of 3-amino-2-fluoro-4-methylpyridine has been investigated by chemists throughout the ages, and there are many records in the classics.
One method is to use a compound containing a pyridine structure as the starting material. Usually a suitable 2-halo-4-methylpyridine is used as the group, and an amino group is introduced first. In this step, ammonia or ammonia derivatives can be selected, and under suitable reaction conditions, such as in a specific solvent, appropriate temperature and pressure are applied to replace the halogen atom with an amino group. This process requires fine regulation of the reaction conditions. The polarity of the solvent and the level of the reaction temperature are all related to the rate of the reaction and the purity of the product.
Furthermore, the pyridine ring structure can be constructed first. Using small molecule compounds containing fluorine, amino group and methyl group as raw materials, the pyridine ring is spliced into a pyridine ring through multi-step reaction. For example, the fluorine-containing carbonyl compound and the amino group and methyl-containing alkenamine compound, under the catalysis of acid or base, through a series of reactions such as condensation and cyclization, the prototype of the pyridine ring is constructed, and then appropriately modified to achieve the synthesis of 3-amino-2-fluoro-4-methylpyridine. There are many steps in this path, and each step needs to be strictly controlled to ensure the smooth progress of each step of the reaction and the correct configuration of the product.
Another method is metal catalysis. Specific metal catalysts, such as palladium, copper, etc., are selected to catalyze the coupling reaction of halogenated pyridine derivatives with reagents containing amino groups, fluorine, and methyl groups. The activity of the metal catalyst, the choice of ligands, and the base and solvent in the reaction system all play a key role in the success or failure of the reaction. This method can often efficiently construct the target molecule, but the reaction conditions are demanding, and the recovery and reuse of the metal catalyst are also factors to be considered.
There are many methods for synthesizing 3-amino-2-fluoro-4-methylpyridine, but each method has its advantages and disadvantages. Chemists need to choose the optimal synthesis method according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction.

I have not obtained the exact price of 3 - Amino - 2 - fluoro - 4 - methylpyridine in the market. However, if you want to know its price, you can ask for it in several ways.
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Third, participate in chemical industry exhibitions and seminars. At such gatherings, chemical companies and experts can communicate with them to explore the price and market conditions of this product. And here you can form more industry contacts to prepare for later purchases.
Fourth, check industry reports and information. There are professional reports and information in the chemical industry, which involve the market status of various chemical products, or contain the price analysis of this product. You can ask for such information in libraries, professional databases, and industry websites to explain their price trends. < Br >
It is difficult to determine the price of 3 - Amino - 2 - fluoro - 4 - methylpyridine because we have not personally observed the market conditions. To determine the price, you need to follow the above methods and compare the information of various sources in detail to obtain the appropriate price.

3-Amino-2-fluoro-4-methylpyridine is also an organic compound. Its storage is essential for its physical properties and safety. This compound has certain chemical activity, so many matters must be paid attention to when storing.
First, it must be placed in a cool place. If the cover temperature is too high, it may cause chemical reactions, damage its quality, or even cause danger. A cool place can slow down the rate of chemical change and maintain the stability of its chemical properties.
Second, drying is essential. Moisture may react with 3-amino-2-fluoro-4-methylpyridine to form impurities and damage its purity. Therefore, when stored in a dry place, or supplemented by a desiccant, to prevent moisture disturbance.
Furthermore, sealed storage is indispensable. This compound may be sensitive to air, exposed to air, or react with gases such as oxygen and carbon dioxide. The sealed device can block the intrusion of external gases and keep its composition pure.
In addition, the storage place should be kept away from fire sources and oxidants. 3-Amino-2-fluoro-4-methylpyridine may be flammable and dangerous in case of fire; and oxidants can also react violently with it, causing accidents.
In addition, storage containers should also be carefully selected. When using corrosion-resistant materials to prevent the container from interacting with the compound, causing damage to the container or contamination of the compound.
In short, the storage of 3-amino-2-fluoro-4-methylpyridine should be cool, dry, sealed, and away from fire sources and oxidants. Choose a suitable container so that its quality and safety can be guaranteed for subsequent use.