3 Amino 2 Chloro 5 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Amino-2-chloro-5-methylpyridine

    Specifications

    HS Code

    868885

    Name 3 - Amino - 2 - chloro - 5 - methylpyridine
    Chemical Formula C6H7ClN2
    Molar Mass 142.586 g/mol
    Appearance Solid (usually)
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Limited solubility (predicted due to non - polar parts in structure)
    Solubility In Organic Solvents Soluble in some common organic solvents like ethanol, acetone
    Density Data may vary, needs experimental determination
    Pka Data may vary, related to its acidic - basic properties in solution
    Flash Point Data may vary, needs experimental determination
    Odor Characteristic, specific to pyridine - based compounds

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 3-Amino-2-chloro-5-methylpyridine?
    3-Amino-2-chloro-5-methylpyridine is an important chemical substance in the field of organic synthesis. It has a wide range of main uses and is often a key intermediate in the field of medicinal chemistry. The unique structure of the Geinpyridine ring gives it the potential to interact with many targets in organisms. By introducing specific functional groups, such as amino groups, chlorine atoms and methyl groups, its chemical and biological properties can be precisely regulated, and then drug molecules with specific pharmacological activities can be synthesized.
    In the field of pesticide chemistry, this substance also occupies an important position. Due to its structural properties, it can be used as a cornerstone for the construction of efficient pesticide molecules. After rational modification and derivatization, new pesticides with high selectivity and strong toxicity to pests can be developed, and the impact on the environment is small, providing a powerful means for agricultural pest control.
    Furthermore, in the field of materials science, 3-amino-2-chloro-5-methylpyridine also shows potential application value. It can participate in the preparation of organic materials with special properties, such as conductive polymers, fluorescent materials, etc. Through ingenious design and reaction, it can be introduced into the material skeleton, which is expected to endow the material with unique electrical and optical properties to meet the needs of high-performance materials in different fields.
    In summary, 3-amino-2-chloro-5-methylpyridine, with its unique structure, has significant uses in various fields such as medicine, pesticides, and materials science, providing an important material foundation and research direction for the development of related fields.
    What are the physical properties of 3-Amino-2-chloro-5-methylpyridine?
    3-Amino-2-chloro-5-methylpyridine is one of the organic compounds. Its physical properties are crucial and related to many practical applications.
    When it comes to appearance, it is usually white to light yellow crystalline powder, which can help visual identification. And it has a certain stability. It encounters strong oxidizing agents, strong acids, strong bases and other substances, or reacts chemically.
    Its melting point range is about a specific range, and this value has a significant impact on its physical state at different temperatures. Above the melting point, it melts into a liquid state. The boiling point also has a corresponding range, which is the key temperature node for its transformation from liquid to gaseous state. The characteristics of boiling point are of great significance in separation and purification operations such as distillation.
    In terms of solubility, in organic solvents such as ethanol and acetone, there is a certain solubility, which makes it possible to choose a suitable solvent in organic synthesis reactions to facilitate the reaction. In water, the solubility is relatively limited, which is also one of its physical properties. When it comes to the operation of aqueous systems, it needs to be taken into account.
    Density is also an important physical property. The specific density value reflects the mass per unit volume. In storage, transportation and related process operations, this characteristic needs to be paid attention to to to ensure the safety and accuracy of operation.
    In summary, the physical properties of 3-amino-2-chloro-5-methylpyridine, such as appearance, melting point, boiling point, solubility, density, etc., play a crucial role in its application in organic synthesis, chemical production, etc. Practitioners must be well informed in order to make good use of it.
    Is 3-Amino-2-chloro-5-methylpyridine chemically stable?
    3-Amino-2-chloro-5-methylpyridine is one of the organic compounds. The stability of its chemical properties is really related to many factors.
    From the perspective of molecular structure, the pyridine ring is aromatic, which gives it a certain stability. The amino group, chlorine atom and methyl group on the ring also affect its stability. The amino group is the electron cloud density of the pyridine ring, which can increase the electron cloud density of the pyridine ring. In some reactions, it may cause the ring to be more prone to electrophilic substitution, which disturbs its stability. Although the chlorine atom has an electron-absorbing induction effect, its conjugation effect is weak, and it also changes the electron cloud distribution of the pyridine ring, which affects the stability of the compound to a certain extent. The methyl group is the power supply group, which can increase the electron cloud density on the ring, and in some situations, it may enhance the stability of the molecule.
    In the chemical environment, if the compound is in a strong acid or strong base environment, the stability may be challenged. The amino group is alkaline and can react with the acid to change the molecular structure. Under the condition of strong base, the chlorine atom may undergo reactions such as nucleophilic substitution, which will reduce its stability. If it is in a high temperature environment, the kinetic energy of the molecule increases, the reactivity also increases, or various decomposition or rearrangement reactions are triggered, which affects its stability.
    In the redox environment, 3-amino-2-chloro-5-methylpyridine may exhibit different stability. The amino group can be oxidized, and if it encounters a strong oxidizing agent, the amino group may be converted into other functional groups, causing the molecular structure to change and the stability to change accordingly.
    Therefore, the chemical stability of 3-amino-2-chloro-5-methylpyridine is not static, but is influenced by its own molecular structure and external chemical and physical environments. Its stability can be determined under specific conditions.
    What are 3-Amino-2-chloro-5-methylpyridine synthesis methods?
    3-Amino-2-chloro-5-methylpyridine is also an organic compound. The synthesis method is quite complicated, and the list of common ones is described here.
    First, using 2-chloro-5-methylpyridine as the starting material, nitro is introduced through nitration reaction, and then nitro is reduced to amino group by appropriate reducing agent, such as iron and hydrochloric acid system, or catalytic hydrogenation method, to obtain the target product. In this process, the nitration reaction needs to be controlled by the reaction conditions. Temperature, acid concentration, etc. all affect the yield and purity of the product. Catalytic hydrogenation requires careful selection of suitable catalysts, such as palladium carbon, and attention to the pressure and reaction time of hydrogen.
    Second, the corresponding pyridine derivative is used as a base to introduce chlorine atoms through halogenation, methylation is performed, and then amino groups are introduced. The halogenation reaction can choose a suitable halogenating agent, such as sulfoxide chloride, etc.; methylation can be done with methylating reagents, such as iodomethane. The method of introducing amino groups can be reduced after diazotization, or by ammonolysis, etc. These steps need to be carefully adjusted according to the characteristics of the compound.
    Third, it is also synthesized by a heterocyclic construction strategy. Through a multi-step reaction, a pyridine ring is gradually built, and chlorine, methyl and amino groups are introduced at an appropriate stage. This path requires a good understanding of the mechanism of heterocyclic synthesis and clever design of the reaction route to achieve the purpose of efficient synthesis.
    All this synthesis method has its own advantages and disadvantages. When it is implemented, it is necessary to carefully choose according to many factors such as the availability of raw materials, cost considerations, difficulty of reaction and purity of the product. Satisfactory results can be obtained.
    What is the price of 3-Amino-2-chloro-5-methylpyridine in the market?
    In today's world, business conditions change, and it is difficult to determine the price of 3-amino-2-chloro-5-methylpyridine on the market. This is due to a variety of reasons intertwined, resulting in its price often fluctuating.
    The first to bear the brunt is the price of raw materials. If the raw materials required for the preparation of this compound are changed due to changes in time, origin, or supply shortage, or a large number of applicants, the price will rise, which in turn will increase the production cost of 3-amino-2-chloro-5-methylpyridine, and the price will also rise. On the contrary, the supply of raw materials is abundant, and the price will stabilize or decrease automatically.
    Furthermore, the coarse process has a great impact on cost and price. If a new and ingenious method can reduce energy consumption, increase yield, and reduce impurities, it will definitely reduce costs and promote low prices. However, if the process is outdated, inefficient, and the cost is high, the price will also be difficult to get close to the people.
    The trend of market supply and demand is also the key. If the demand for this compound in the fields of medicine, pesticides, etc. increases sharply, but the supply is limited, the price will rise as the tide rises. On the contrary, the demand is sluggish and the supply is excessive, and merchants have to reduce prices in order to sell their goods.
    In addition, external forces such as policies and regulations and the international situation should not be underestimated. New regulations on environmental protection, production is limited, and costs may rise; international trade disputes, tariff changes, and transportation blockages can all cause price fluctuations.
    To sum up, in order to know the current market price of 3-amino-2-chloro-5-methylpyridine, it is necessary to observe the raw material market, process progress, supply and demand changes and policy situations in real time, and study in detail to obtain a relatively accurate number.