3-Amino-2-bromo-6-chloropyridine

3-Amino-2-bromo-6-chloropyridine is an important class of organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Taking the synthesis of specific drug molecules as an example, due to the unique activities of amino groups, bromine atoms and chlorine atoms in the structure, it can be connected with other organic fragments through various chemical reactions to construct a complex drug structure with specific physiological activities.
In the field of pesticide chemistry, it also shows its important value. With reasonable chemical modification, pesticides can be prepared that have high inhibition or killing effects on specific pests or pathogens. This is because its special chemical structure can interact with specific biomacromolecules in pests or pathogens, interfering with their normal physiological metabolic processes.
Furthermore, in the field of materials science, 3-amino-2-bromo-6-chloropyridine may participate in the synthesis of functional materials. For example, by polymerizing with specific monomers, polymer materials with special optical, electrical or mechanical properties can be prepared, opening up new paths for the research and development of new materials.
In summary, 3-amino-2-bromo-6-chloropyridine has critical uses in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related fields.

3-Amino-2-bromo-6-chloropyridine is one of the organic compounds. Its physical properties are of great interest and are of great significance in many fields of chemistry.
First of all, its appearance, at room temperature and pressure, the compound is usually white to light yellow crystalline powder. This appearance characteristic is easy to identify and is consistent with many similar properties of organic compounds. Its color and morphology are affected by molecular structure and intermolecular interactions.
Furthermore, when it comes to melting point, the melting point of this substance is about a specific temperature range, and this value is crucial for determining its purity and behavior in specific chemical reactions. The determination of melting point can be achieved by precision instruments such as melting point meters. Accurate melting point data can provide a key basis for the identification and quality control of compounds.
In terms of solubility, 3-amino-2-bromo-6-chloropyridine exhibits specific solubility properties in common organic solvents. In some organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), it has certain solubility, but its solubility in water is relatively limited. This difference in solubility is mainly due to the amino, bromine and chlorine atoms contained in its molecular structure. These functional groups affect the polarity of the molecule, which in turn determines its solubility in different solvents.
Volatility is also a key factor in considering its physical properties. Due to its relatively stable molecular structure, the volatility of 3-amino-2-bromo-6-chloropyridine is low. This property makes it less susceptible to loss due to volatilization during storage and use, which facilitates its laboratory operation and industrial applications.
In addition, the density of the compound is also a specific value. Although its density is not as frequently used for characterization as melting point and solubility, in some specific situations, such as in processes involving accurate measurement and mixing, density data is also indispensable.
In conclusion, the physical properties of 3-amino-2-bromo-6-chloropyridine, such as appearance, melting point, solubility, volatility, and density, are interrelated and affect their application in organic synthesis, medicinal chemistry, and other fields. In-depth understanding of these properties will enable more effective use of this compound in various chemical processes.

The synthesis method of 3-amino-2-bromo-6-chloropyridine, although the ancient book "Tiangong Kaiwu" does not contain this substance, it can be compared with the ancient chemical process thought.
To synthesize this substance, you can start from pyridine. First, use pyridine as a base and introduce bromine and chlorine atoms by halogenation. In a suitable reaction vessel, such as a porcelain kettle, add pyridine, and use suitable halogenating agents, such as brominating agents and chlorinating agents, to control the temperature and reaction time. Taking bromination as an example, liquid bromine and a suitable catalyst can be selected. At a specific temperature, bromine and pyridine are substituted, and bromine atoms are first introduced at suitable positions in the pyridine ring. Similarly, chlorine atoms are introduced with a chlorinating agent. This process requires fine control of the reaction conditions. Due to the different substitution activities at different positions on the pyridine ring, to obtain 2-bromo-6-chloropyridine, suitable reaction parameters such as temperature and ratio of reactants need to be found.
Second, after 2-bromo-6-chloropyridine is obtained, an amino group is introduced. This can be achieved by ammonolysis reaction. 2-Bromo-6-chloropyridine is placed in a reactor, liquid ammonia or ammonia gas is added with a suitable solvent, and the reaction is under a certain pressure and temperature. The nitrogen atom in the ammonia molecule is nucleophilic and can replace the bromine or chlorine atom, thereby introducing the amino group. However, this process also needs to pay attention to the occurrence of side reactions, such as the formation of polysubstituted products. Therefore, the reaction conditions need to be carefully selected. Different catalysts, temperature and pressure combinations can be tried to improve the yield and purity of the target product 3-amino-2-bromo-6-chloropyridine. The way of synthesis requires repeated trials, detailed observation of the reaction phenomenon, and precise control of the conditions.

3-Amino-2-bromo-6-chloropyridine, the price of this compound in the market often fluctuates due to many factors. Looking at the changes in the market of chemical materials in the past, first, the difficulty of preparation and the abundance of raw materials are the keys to affecting the price. If the preparation process is complicated, and the required raw materials are scarce and difficult to find, or the price of raw materials is affected by the season, origin, and market supply and demand, the production cost of this compound will increase, and the price will also rise.
Second, the state of market demand also affects its price. If there is a strong demand for it in the fields of pharmaceutical synthesis, pesticide research and development, but the supply is relatively insufficient, according to the reason of supply and demand, the price will rise; on the contrary, if the demand is weak and the supply exceeds the demand, the price will inevitably fall.
Furthermore, the state of industry competition is also relevant. If there are many manufacturers and the competition is fierce, there may be price cuts in order to compete for market share; however, if the market is controlled by a few manufacturers, it is monopolistic, and the price is easily controlled by it.
According to the past transactions of chemical products and the price of similar compounds, the price of 3-amino-2-bromo-6-chloropyridine per gram may hover between tens of yuan and hundreds of yuan. However, this is only an approximate number. The actual price should be subject to the current market inquiry. To know the exact price, you need to consult chemical raw material suppliers and reagent sellers in detail, and compare the quotations from multiple parties to clarify.

3-Amino-2-bromo-6-chloropyridine is an organic compound, and its storage conditions are quite critical, which is related to material stability and quality. According to the traditional method of "Tiangong Kaiwu", when it comes to the storage of such compounds, the first environmental choice should be selected.
First, it should be placed in a cool place. Due to high temperature, it is easy to accelerate chemical reactions, or cause 3-amino-2-bromo-6-chloropyridine to decompose and deteriorate. If it is placed in hot summer and placed under the scorching sun, the internal structure of the compound may be affected, thereby damaging its chemical properties.
Second, it needs to be kept dry. Moisture is often the cause of many chemical reactions. 3-amino-2-bromo-6-chloropyridine may be hydrolyzed in contact with water, or undergo other complex reactions with water. Therefore, the storage place should not be humid, and it is appropriate to use a desiccant to keep the environment dry, such as traditional desiccants such as lime, or modern desiccant silica gel, etc., to prevent the compound from contacting with water vapor.
Third, sealed storage is indispensable. Gases such as oxygen and carbon dioxide in the air may react with 3-amino-2-bromo-6-chloropyridine. Sealing can prevent it from contacting with air components. Commonly used sealed containers, such as glass bottles, are sealed with rubber stoppers or glass stoppers. Plastic bottles can also be used, but it is necessary to ensure that the plastic material does not react with compounds.
Fourth, the storage place should be away from fire sources and strong oxidants. 3-Amino-2-bromo-6-chloropyridine may be flammable, and it is easy to catch fire or even explode in case of fire sources; strong oxidants can cause violent oxidation reactions, causing danger. < Br >
In this way, 3-amino-2-bromo-6-chloropyridine can be stored in a cool, dry, sealed condition away from ignition and strong oxidants to ensure its chemical stability and quality.