3 Amino 2 6 Dimethylpyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Amino-2,6-dimethylpyridine

    Specifications

    HS Code

    752543

    Chemical Formula C7H10N2
    Molar Mass 122.17 g/mol
    Appearance Solid
    Color White to off - white
    Odor Characteristic amine - like odor
    Melting Point 63 - 67 °C
    Boiling Point 251 - 253 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Pka ~10.5
    Density 1.03 g/cm³ (estimated)

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    General Information
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    Frequently Asked Questions

    As a leading 3-Amino-2,6-dimethylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-amino-2,6-dimethylpyridine?
    3-Hydroxy-2,6-dimethylpyridine, this substance has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help synthesize many specific drugs. Due to its unique chemical structure, it can impart specific activities and properties to drug molecules. Like some antibacterial drugs, it can improve the antibacterial efficacy and pertinence, and better inhibit the growth and reproduction of pathogens.
    In the field of pesticides, it also plays an important role. It can be used to create new pesticides, showing efficient control effects on pests. By interacting with specific targets in the body of pests, it interferes with their normal physiological activities, achieving effective control of pests, and has a relatively small impact on the environment, which is in line with the development needs of modern green agriculture.
    In the field of materials science, 3-hydroxy-2,6-dimethylpyridine can participate in the preparation of high-performance materials. For example, in the synthesis of polymer materials, as a functional monomer or additive, optimize the properties of materials, such as enhancing the stability, heat resistance and mechanical strength of materials, and expand the practical application of materials.
    This compound is an important cornerstone in the field of organic synthesis. With its active hydroxyl and methyl groups, it can carry out a variety of chemical reactions and realize the construction of various complex organic compounds, providing strong support for the development of organic synthetic chemistry and promoting continuous innovation and progress in related fields.
    What are the physical properties of 3-amino-2,6-dimethylpyridine?
    3-Amino-2,6-dimethylpyridine is a kind of organic compound. Its physical properties are quite unique, let me tell them one by one.
    Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid. Its appearance is quite recognizable, and the texture is uniform and pure.
    When it comes to the boiling point, it is about 195-198 ° C. This boiling point condition makes the substance change from liquid state to gaseous state in a specific temperature environment. Such characteristics are of key guiding significance in the distillation, separation and other processes of chemical production.
    Its melting point is roughly -15 ° C. The value of the melting point indicates that when the external temperature drops to this point and below, the compound will solidify from liquid to solid. Knowing the melting point is of great significance in storage and transportation, so that suitable temperature conditions can be selected accordingly to ensure that the substance maintains the desired form.
    In addition, the density is about 0.963g/cm ³. The property of density reflects the mass of the substance per unit volume, and is an indispensable reference index in operations involving the mixing and proportioning of substances.
    As for solubility, 3-amino-2,6-dimethylpyridine is soluble in many common organic solvents, such as ethanol and ether. However, the solubility in water is relatively limited. This solubility characteristic determines its dispersion and reaction characteristics in different solvent environments, and provides an important basis for chemists in the solvent selection step of organic synthesis.
    In summary, the various physical properties of 3-amino-2,6-dimethylpyridine are interrelated and affect each other, and play an important role in the research and production practice of many fields such as chemical industry and medicine.
    What are the synthesis methods of 3-amino-2,6-dimethylpyridine?
    To prepare 3-amino-2,6-dimethylpyridine, the method is as follows:
    First, take 2,6-dimethylpyridine as the starting material, and obtain 3-nitro-2,6-dimethylpyridine by nitrification. This process requires careful selection of nitrifying reagents, such as concentrated nitric acid and concentrated sulfuric acid mixed acid, and control the reaction temperature and time to prevent side reactions from occurring. After the method of reduction, the nitro group is converted into an amino group. Iron powder, hydrochloric acid, sodium sulfide and other reduction systems can be selected. Catalytic hydrogenation can also be used. Palladium carbon, platinum carbon, etc. are used as catalysts to reduce hydrogen to obtain the target product 3-amino-2,6-dimethylpyridine.
    Second, it can be condensed and cyclized. Using suitable nitrogen-containing compounds and dicarbonyl compounds as raw materials, under the catalysis of bases or acids, pyridine rings are constructed by condensation and cyclization. For example, acetylacetone is reacted with ammonia or amino-containing compounds under appropriate conditions, through cyclization, dehydration and other steps, to obtain 2,6-dimethylpyridine intermediates, and then through subsequent modifications, such as the introduction of amino groups, to obtain 3-amino-2,6-dimethylpyridine. This route requires fine regulation of the reaction conditions so that the reaction proceeds according to the expected path.
    Third, halogenated pyridine can also be used as a raw material. First, 2,6-dimethyl-3-halogenated pyridine is prepared, with halogen atoms such as chlorine, bromine, etc. After nucleophilic substitution reaction, ammonia or amine reagents are used to replace halogen atoms to obtain 3-amino-2,6-dimethylpyridine. In the reaction, the activity of halogenated pyridine should be considered, and appropriate nucleophilic reagents and reaction conditions should be selected to improve the yield and purity of the product.
    What should be paid attention to when storing and transporting 3-amino-2,6-dimethylpyridine?
    3-Amino-2,6-dimethylpyridine is also a chemical substance. When storing and transporting, pay attention to many matters.
    First words storage, this substance should be placed in a cool, dry and well-ventilated place. Because the cool environment can prevent its chemical properties from changing due to excessive temperature, the dry state can avoid its reaction caused by moisture, and good ventilation can disperse harmful gases that may accumulate. And it needs to be kept away from fires and heat sources, because the substance may be flammable, and it is easy to brew in case of open flames and hot topics. In addition, it should be stored separately from oxidants, acids, etc., due to contact with it, or severe chemical reaction, resulting in safety accidents.
    As for transportation, there are also many important requirements. Transportation vehicles must ensure that they are in good condition and have corresponding fire and explosion-proof devices. During transportation, they should be protected from exposure to the sun, rain, and high temperature. When loading and unloading, the operator should be light and light, and it is strictly forbidden to drop and heavy pressure to avoid material leakage due to package damage. If the material leaks, emergency measures should be taken quickly to evacuate the surrounding personnel, isolate the leaked pollution area, and select suitable materials for containment and handling according to its characteristics. Transport personnel should also be familiar with the dangerous characteristics of the substance and emergency treatment methods, so that they can properly respond to emergencies and ensure the safety of transportation.
    What is the market prospect of 3-amino-2,6-dimethylpyridine?
    3-Hydroxy-2,6-dimethylpyridine, this product is in the market and has a promising future. It has a wide range of uses and is a key raw material for the synthesis of many drugs in the field of medicine. The preparation of many antibacterial and anti-inflammatory drugs depends on its participation. With the increasing demand for high-efficiency and safe drugs in the pharmaceutical industry, the demand in this field continues to rise.
    In the field of pesticides, it can be used as an intermediate for the synthesis of new pesticides. Modern pesticides pursue low toxicity, high efficiency and environmental protection. The pesticides synthesized by 3-hydroxy-2,6-dimethylpyridine are in line with this trend and play an important role in the control of crop diseases and insect pests, and the market demand is growing steadily.
    In the field of materials science, it can be used to synthesize special polymer materials. With the advancement of science and technology, the demand for high-performance materials is rising. Materials synthesized from this raw material have emerged in high-end fields such as electronics and aerospace, and the future market potential is huge.
    Furthermore, its synthesis process is also continuously optimized. The emergence of new synthesis methods has reduced production costs and increased productivity, further enhancing its market competitiveness. Many scientific research institutions and enterprises are focusing on this, and R & D investment continues to increase, which is expected to lead to more innovative applications and products. In summary, the market prospect of 3-hydroxy-2,6-dimethylpyridine is promising, and it will play an increasingly important role in many fields. The market scale will also continue to expand.