3 Acetyl 2 Ethoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Acetyl-2-ethoxypyridine

    Specifications

    HS Code

    520824

    Chemical Formula C9H11NO2
    Molar Mass 165.19 g/mol
    Appearance Typically a liquid (appearance can vary based on purity and conditions)

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    General Information
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    Frequently Asked Questions

    As a leading 3-Acetyl-2-ethoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Acetyl-2-ethoxypyridine?
    3-Acetyl-2-ethoxypyridine is also an organic compound. It has a wide range of uses and has important applications in chemical, pharmaceutical and other fields.
    In the chemical industry, it is often a key intermediate for the synthesis of other complex organic compounds. Due to its special chemical structure, it can interact with many reagents through various chemical reactions, such as substitution reactions, addition reactions, etc., to build more complex organic molecular structures, laying the foundation for the preparation of materials with specific properties.
    In the field of medicine, the role of this compound should not be underestimated. Or it can be used as a lead compound, modified and optimized to develop drugs with specific pharmacological activities. In the process of drug research and development, or participate in the regulation of physiological and biochemical processes in organisms, such as affecting the activity of specific enzymes, or interfering with cell signaling pathways, thus exhibiting potential therapeutic effects, and is expected to be used in the treatment of a variety of diseases, such as inflammation, tumors, etc.
    Furthermore, in the field of materials science, 3-acetyl-2-ethoxypyridine or because of its unique physical and chemical properties, such as intermolecular force, solubility, etc., can be used to prepare materials with special properties, such as optical materials, polymer materials, etc., endowing materials with unique functions, such as fluorescence properties, excellent mechanical properties, etc. From this perspective, 3-acetyl-2-ethoxypyridine, with its unique structure and properties, plays an important role in many fields such as chemical engineering, medicine, and materials science, promoting the development and progress of various fields.
    What are the physical properties of 3-Acetyl-2-ethoxypyridine?
    3-Acetyl-2-ethoxypyridine is a kind of organic compound. Its physical properties are particularly important, and it is related to its application and treatment.
    First of all, its appearance is usually liquid, and the color is close to colorless to light yellow. The appearance is clear, like morning dew, pure and free of noise. This appearance sign can help identify among various compounds.
    Second, its boiling point is about a certain temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gas. The boiling point of this compound enables it to achieve phase change at a specific temperature. When heated to this temperature, the molecule is energized, breaks free from the liquid phase and rises into the gas phase. This property is very useful in the process of separation and purification. It can be extracted from the mixture by distillation according to the difference in boiling point.
    Furthermore, the melting point is also an important physical property. Although it is liquid at room temperature, it cools down to a specific low temperature and condenses into a solid state. The exact value of the melting point is like the "solid threshold" of a substance. It is a key indicator of its physical properties and can be used for quality identification. The melting point of pure products and impurity mixtures is often significantly different.
    The solubility cannot be ignored. 3-Acetyl-2-ethoxypyridine often has good solubility in organic solvents, such as ethanol and acetone, and can blend with solvent molecules, just like fish swimming in water, free and unhindered. However, in water, its solubility is relatively limited, which is related to the polarity of the molecule. Due to its molecular structure, the force between it and water molecules is weak, making it difficult to dissolve into water in large quantities.
    density is another characteristic. Its density is specific, slightly heavier or lighter than water, which is related to its position distribution in the mixed system. In the stratification experiment, it can be layered with other substances according to different densities, which provides convenience for the separation operation.
    In addition, its volatility also needs attention. Although it is not highly volatile, under certain conditions, such as rising temperature and well-ventilated areas, molecules will also escape into the air. This volatility needs to be prevented during storage and use to avoid loss and safety risks.
    In summary, the physical properties, appearance, boiling point, melting point, solubility, density and volatility of 3-acetyl-2-ethoxypyridine are of great significance in the fields of organic synthesis and chemical analysis, and are well known to users.
    Is 3-Acetyl-2-ethoxypyridine chemically stable?
    The stability of the chemical properties of 3-acetyl-2-ethoxy pyridine depends on many aspects. Looking at the structure of this compound, both acetyl and ethoxy groups are connected to the pyridine ring. The pyridine ring is aromatic and has a certain stability. However, the substituents on the ring also have a significant impact on its chemical properties.
    Acetyl group has a carbonyl structure. This carbonyl group can participate in a variety of chemical reactions, such as nucleophilic addition reactions. Because its carbonyl carbon is partially positive, it is vulnerable to attack by nucleophilic reagents. When encountering nucleophiles, nucleophiles can attack carbonyl carbons and cause them to react. It can be seen that this part of the structure may reduce the stability of the compound slightly.
    Furthermore, the ethoxy group is attached to the pyridine ring, and the oxygen in the ethoxy group has a lone pair of electrons, which can have an electronic effect with the pyridine ring. This electronic effect may affect the electron cloud density distribution of the pyridine ring, which in turn affects its reactivity. If the electron cloud density changes, the compound may be more prone to react under certain reaction conditions, and the stability will also change accordingly.
    Under different reaction environments, such as pH and temperature, the stability of 3-acetyl-2-ethoxylpyridine is also different. In a strongly acidic environment, the pyridine ring or protonation causes its electronic structure to change, which in turn affects the stability and reactivity of the entire molecule. Under high temperature environments, the vibration of chemical bonds within the molecule intensifies, or it may lead to the breaking of chemical bonds, resulting in a decrease in its stability.
    Overall, the chemical properties of 3-acetyl-2-ethoxylpyridine are not absolutely stable, but are affected by the interaction of various parts in its structure and external reaction conditions. Its stability is in a state of dynamic change, and it needs to be judged according to specific reaction scenarios and conditions.
    What are 3-Acetyl-2-ethoxypyridine synthesis methods?
    The synthesis method of 3-acetyl-2-ethoxy pyridine has been around for a long time, and the method has been evolving over the years. Today I will describe them in detail.
    First, using 2-ethoxy pyridine as the starting material, 3-acetyl-2-ethoxy pyridine can be prepared by acylation reaction. In this process, acetylation reagents, such as acetyl chloride or acetic anhydride, are often used in the presence of suitable catalysts. Catalysts, such as Lewis acids such as aluminum trichloride, can promote the reaction. When reacting, pay attention to the control of reaction temperature and time. If the temperature is too high, it may cause side reactions to occur, which affects the purity of the product; if the time is too short, the reaction may be incomplete, and the yield will decrease. Generally speaking, the reaction starts in the range from low temperature to room temperature, and then the temperature rises moderately depending on the reaction process. After several hours, the product can be obtained by separation and purification.
    Second, the pyridine ring can be modified first, and a suitable substituent can be introduced, and then the acetyl group and ethoxy group can be constructed through a series of reactions. For example, a halogen atom is introduced at a specific position in the pyridine ring first, then an ethoxy group is introduced through a nucleophilic substitution reaction, and finally an acetyl group is added through an acylation reaction. This approach is slightly more complicated, and the control of the reaction conditions is more accurate, which can effectively
    Furthermore, there is a method that starts with a natural product or simple compound containing a pyridine structure and converts it into 3-acetyl-2-ethoxypyridine through a multi-step reaction. This method requires in-depth understanding of the structure and reactivity of the starting material, and gradually realizes the synthesis of the target product with ingenious reaction design.
    All this synthesis method has advantages and disadvantages. In practical applications, it is necessary to carefully select the appropriate synthesis path according to the availability of raw materials, cost, product purity and yield, etc., in order to achieve the purpose of efficient and economical synthesis.
    What is the price range of 3-Acetyl-2-ethoxypyridine in the market?
    The price range of this 3-acetyl-2-ethoxypyridine product in the market is difficult to determine with certainty. The price often varies due to various factors.
    First, the price of raw materials. If the raw materials used in the synthesis of this pyridine are difficult to obtain and the amount can affect the cost, which in turn affects the market price. If the raw materials are scarce and difficult to find, the price must be high; if the raw materials are abundant and easy to obtain, the price may be slightly lower.
    Second, the method of preparation, the complexity of different preparation processes, the required energy consumption, and the yield are all related to the cost. If the process is complicated, the energy consumption is high and the yield is low, the cost will increase, and the market price will also be high; conversely, if the process is simple, the energy consumption is low and the yield is high, the price may decrease.
    Third, the market supply and demand, if the demand for pyridine is strong, but the supply is limited, the merchant will raise the price due to it; if the demand is weak and the supply is excessive, the price will be calculated for sales or lowered.
    Fourth, the difference between manufacturers and quality, made by different manufacturers, due to different technologies and quality control, the quality is different, and the price is also different. Probably well-known manufacturers and those with excellent quality have slightly higher prices; unknown manufacturers and those with inferior quality have lower prices.
    According to the price changes of various chemical products in the past, the price of this 3-acetyl-2-ethoxypyridine per gram may range from a few yuan to tens of yuan. However, this is only a rough test, and the actual price still needs to be carefully checked by various merchants in the current market to obtain an accurate number.