3-Acethyl-6-hydroxypyridine

3-Acetyl-6-hydroxypyridine has a wide range of uses. In the field of medicine, this compound can be used as a key intermediate to assist in the synthesis of various drugs with special pharmacological activities. Its unique structure may be compatible with specific targets in organisms, thus showing the potential to treat diseases, such as in the development of anti-tumor, anti-viral drugs, etc.
In the field of material chemistry, 3-acetyl-6-hydroxypyridine also has potential applications. Due to its specific functional groups, it can participate in the construction of functional materials, such as for the preparation of materials with special optical and electrical properties, or in the field of sensor materials, through the interaction with specific substances, to achieve sensitive detection of specific components.
Furthermore, in organic synthetic chemistry, as an important raw material, it can derive many organic compounds with novel structures through various chemical reactions, expand the variety of organic compounds, and contribute to the development of organic synthetic chemistry. Chemists can skillfully design reaction paths based on their structural characteristics, synthesize more complex and unique organic molecules, enrich the treasure trove of organic compounds, and promote progress in the field of organic synthesis.

3-Acetyl-6-hydroxypyridine is one of the organic compounds. Its physical properties are quite important and are related to many chemical applications.
Looking at its appearance, under room temperature, it is often white to light yellow crystalline powder. This form is easy to store and use, and in many reaction systems, the state of the powder can provide a large surface area, which is conducive to the efficient progress of the reaction.
When it comes to the melting point, it is within a certain range. This property can be used for the identification of purity. Cover pure 3-acetyl-6-hydroxypyridine, the melting point is relatively fixed. If it contains impurities, the melting point will often change, or decrease, or the melting range will become wider.
Solubility is also a key physical property. In common organic solvents, it exhibits a specific dissolution behavior. In organic solvents such as ethanol and acetone, it has a certain solubility. This property makes it possible to choose a suitable solvent according to the reaction requirements in organic synthesis to promote the smooth progress of the reaction. However, in water, the solubility is relatively limited. This difference is closely related to the structure of the molecule. There are both lipophilic acetyl groups in the molecule, and hydrophilic hydroxyl groups and pyridine rings, which lead to the overall difference in its dissolution characteristics in water and organic solvents.
In addition, the stability of 3-acetyl-6-hydroxypyridine is also worthy of attention. Under normal storage conditions, it can maintain a relatively stable chemical structure. However, under extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may change, which in turn affects its physical properties.
In summary, the physical properties of 3-acetyl-6-hydroxypyridine, such as appearance, melting point, solubility, and stability, are of great significance in chemical research, organic synthesis, and related industrial applications, providing a solid foundation for the rational use of this compound.

There are various methods for the synthesis of 3-acetyl-6-hydroxypyridine. One common method is to use 6-hydroxypyridine as the starting material, so that it can react with acetylation reagents, such as acetyl chloride or acetic anhydride, under appropriate reaction conditions. During the reaction, suitable solvents, such as dichloromethane, pyridine, etc., need to be selected to facilitate the reaction. Under the catalysis of bases, acetyl groups can be successfully introduced into the 3-position of 6-hydroxypyridine. Bases can be selected from triethylamine, pyridine, etc., which can promote the occurrence of reactions and improve yields.
Furthermore, pyridine derivatives containing corresponding substituents can also be prepared as raw materials through multi-step reactions. For example, pyridine intermediates containing appropriate protective groups are prepared first, and then 3-acetyl-6-hydroxypyridine is obtained through deprotection, acetylation and other steps. Although this approach is a little complicated, it can effectively control the reaction check point and product purity.
Or it can be synthesized by coupling reaction catalyzed by transition metals. Halogenated pyridine derivatives and acetylation reagents are used in transition metal catalysts, such as palladium catalysts, to realize the construction of carbon-carbon bonds or carbon-heteroatomic bonds, and then to generate the target product. This method has mild conditions and good selectivity, and is increasingly used in the field of organic synthesis.
There are many methods for synthesizing 3-acetyl-6-hydroxypyridine, each with its own advantages and disadvantages. The most suitable method should be selected according to actual needs, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product, etc., in order to achieve the purpose of efficient and high-purity synthesis.

I look at your question, but I am inquiring about the price range of 3-acetyl-6-hydroxypyridine in the market. However, the price of these chemicals often varies due to various factors, making it difficult to determine the number.
First, the situation of supply and demand is the main reason. If there are many people who want this product, but there are few producers, the price will increase; if the supply exceeds the demand, the price will decrease. Second, the cost of production also has a great impact. The price of raw materials, energy consumption, and labor are all related to their cost. If the cost is high, the selling price will also be high. Third, the quality is different, and the price is different. Those with high purity and high quality should be higher than those with ordinary quality. Fourth, the purchase quantity is different, and the price is also different. Buy in bulk, and often get a preferential price.
In the past, the price of such chemicals per gram may be between a few and tens of dollars. However, today is different from the past, and the market conditions are unpredictable. To know the exact price, you should consult chemical suppliers, traders, or check in detail on relevant chemical trading platforms. In this way, you can get the current real price range.

3-Acetyl-6-hydroxypyridine is a chemical substance. Its storage conditions are crucial and related to the stability and quality of this substance.
To properly store this 3-acetyl-6-hydroxypyridine, the first dry environment. Moisture is often the enemy of many chemicals, which can cause adverse reactions such as hydrolysis to occur, damaging its purity and activity. Therefore, when placed in a dry place, if in a laboratory, desiccants can be prepared in storage places, such as calcium chloride, silica gel, etc., to absorb water vapor in the air and ensure a dry environment.
Secondary and temperature control. It should be stored in a cool place away from high temperatures. High temperatures can accelerate the rate of chemical reactions, or cause adverse changes such as decomposition and polymerization. Generally speaking, it is best to store in a refrigerated environment of 2-8 degrees Celsius. If conditions are limited, it should also be placed at a place not higher than 25 degrees Celsius.
Furthermore, protection from light cannot be ignored. Light can initiate photochemical reactions, which affect the structure and properties of 3-acetyl-6-hydroxypyridine. Therefore, the storage container should be protected from light, such as brown glass bottles, which can effectively block light and protect the substance from light damage.
In addition, the storage place should be kept away from fire sources, oxidants and other dangerous items. 3-Acetyl-6-hydroxypyridine may have certain chemical activity, and may be dangerous when exposed to fire sources or oxidants, or react violently. And should be placed separately from other chemical substances to prevent mutual contamination and reaction.
Properly store 3-acetyl-6-hydroxypyridine, pay attention to dry, cool, dark and isolated dangerous substances, so as to ensure the stability and availability of this substance.