3 6 Dichloro 2 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

3,6-DICHLORO-2-(TRIFLUOROMETHYL)PYRIDINE

    Specifications

    HS Code

    465433

    Chemical Formula C6H2Cl2F3N
    Molecular Weight 215.987
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Approximately 162 - 164 °C
    Density Around 1.55 g/cm³
    Vapor Pressure Relatively low, but data may vary with temperature
    Solubility In Water Low solubility in water, considered hydrophobic
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Flash Point Caution: May be flammable, specific flash - point data needed

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    Frequently Asked Questions

    As a leading 3,6-DICHLORO-2-(TRIFLUOROMETHYL)PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,6-dichloro-2- (trifluoromethyl) pyridine?
    3% 2C6 -dioxo-2- (triethylmethyl) pyridine, this substance was not available in the era covered by Tiangong Kaiwu, so it is difficult to record its use in the book. However, in today's view of chemical knowledge, such compounds have a wide range of uses in the field of organic synthesis.
    First, it can be used as a key intermediate in organic synthesis. Because of its unique activity, it can be linked with other organic molecules by many chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to build complex organic structures. For example, in the field of medicinal chemistry, it can be introduced into the molecular framework of drugs through a series of reactions to adjust the activity, solubility, stability and other characteristics of drugs. For example, in the total synthesis of some natural products with specific biological activities, such pyridine derivatives may be the key synthetic building blocks, assisting chemists in constructing complex structures similar to natural products and promoting the development of innovative drugs.
    Second, it also has potential applications in the field of materials science. Due to the electronic properties of pyridine rings, their derivatives may endow materials with special electrical and optical properties. For example, through rational molecular design and synthesis, materials with specific photoelectric properties may be prepared for use in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve device performance and efficiency.
    Third, in the field of catalysis, such compounds may be used as ligands. After complexing with metal ions, the formed metal complexes may have unique catalytic activity and selectivity. They can be used as efficient catalysts in various organic reactions, such as hydrogenation reactions and oxidation reactions, to promote the reaction and improve the reaction yield and selectivity. This is of great significance to the development of organic synthesis chemistry.
    What are the physical properties of 3,6-dichloro-2- (trifluoromethyl) pyridine?
    3% 2C6 -dioxo-2- (triethylmethyl) pyridine This substance has quite unique physical properties.
    Looking at its shape, under normal conditions, it may be a colorless to light yellow liquid with a clear and transparent texture. Under light, its radiant luster can be seen, just like autumn water.
    Smell its smell and emit a little special smell. Although it is not pungent, it is unique. It seems to have a subtle fragrance. Under the sniff, you can feel its unique charm.
    In terms of its solubility, it shows good solubility in many organic solvents. It can be miscible with common organic solvents such as ethanol and ether in any ratio, just like water and milk, regardless of each other. This property makes it have extraordinary application potential in organic synthesis and other fields, just like a key that can open the door to many chemical reactions.
    When it comes to density, compared to water, its density is slightly higher than that of water. When it is placed in the same place as water, it can be seen that it sinks slowly, like a calm walker, not floating or impatient, and falls calmly to the bottom of the water, highlighting its unique density properties.
    Looking at its boiling point, it has a certain boiling point value. Under specific pressure conditions, it needs to reach the corresponding temperature in order to transform it from liquid to gas and start the journey of gasification. This boiling point property is like a beacon in the separation, purification and other operations, guiding the experimenter in the right direction and helping to accurately control the morphological changes of the substance.
    And the melting point is also one of its important physical properties. Under a specific low temperature environment, this substance will gradually solidify from liquid to solid, just like winter water condenses into ice, showing the regularity and stability of the solid state. The exact value of its melting point also provides a key basis for the identification and study of this substance.
    These various physical properties together outline the unique physical "portrait" of 3% 2C6 -dioxo-2- (triethyl) pyridine, which lays a solid foundation for its application in scientific research, industry and many other fields.
    Is the chemical property of 3,6-dichloro-2- (trifluoromethyl) pyridine stable?
    The chemical properties of 3% 2C6-dioxy-2- (triethylmethyl) furan are still stable.
    Looking at its structure, it contains dioxy and furan groups, and triethyl groups are attached to it. The dioxy structure in the molecule can cause a specific state of electron cloud distribution, but because of its proper bond energy configuration, it is not a source of strong stimulation and is difficult to change. Furan ring has a certain aromaticity, and this aromatic system endows its molecules with a certain degree of stability, making it difficult to react with its surroundings under conventional temperature and pressure conditions.
    Again, triethyl group, which is a large substituent, has a steric resistance effect. This effect, to a certain extent, builds a "protective wall" for the molecule. If foreign reagents want to interact with the core part of the molecule, they need to break through this space barrier first. And the electronic effect of triethyl methyl may have the power to adjust the electron cloud density of the molecule as a whole, but this modulation is also within the scope of maintaining molecular stability.
    Under normal circumstances, if there is no extreme conditions such as strong acid, strong alkali, strong oxidant or high temperature and high pressure, 3% 2C6 -dioxy-2- (triethyl) furan is in the environment, and its chemical properties are stable, so it will not change violently for no reason.
    What are the synthesis methods of 3,6-dichloro-2- (trifluoromethyl) pyridine?
    The synthesis of 3% 2C6 -dioxo-2- (triethylmethyl) heptane is an important topic in organic synthetic chemistry. There are many synthesis paths, and the following are common methods:
    First, react with metal-organic reagents with suitable halogenated hydrocarbons. The halogenated hydrocarbons are carefully selected, such as halogenates with specific carbon chain structures and halogenated atoms, and Grignard reagents made of metal magnesium. In an anhydrous ether and other inert solvent environment, the two meet and undergo nucleophilic substitution. The carbon anion part of the Grignard reagent attacks the carbon atoms connected to the halogenated hydrocarbons, and the halogenated atoms leave, forming a carbon-carbon bond, which lays the foundation for the carbon skeleton of the target product. Subsequent to the conversion of appropriate functional groups, 3% 2C6-dioxy-2- (triethylmethyl) heptane can be obtained.
    Second, it is constructed by the reaction of aldons and ketones. Aldodes or ketones, with specific alcohols, can undergo condensation reactions under the catalysis of acids or bases. For example, an aldehyde and an alcohol with suitable substituents, when catalyzed by acids, the hydroxyl oxygen of the alcohol attacks the nucleophilic attack of the carbonyl carbon of the aldehyde through a series of proton transfer and dehydration steps to form an enol ether intermediate. This intermediate can be converted into the target 3% 2C6-dioxy-2 - (triethylmethyl) heptane by subsequent reactions such as reduction.
    Third, the cyclization reaction strategy is used. A chain-like compound with an appropriate functional group is selected, and a cyclic structure is formed through an intramolecular reaction to conform to the dioxy ring part of the target product. For example, a chain-like compound containing hydroxyl groups and halogen atoms, under the action of a strong base, the carbon atoms connected to the halogen atoms and hydroxyl groups in the molecule undergo nucleophilic substitution and cyclization to form a dioxy ring. Subsequently, the carbon chain outside the ring is modified, and triethyl groups such as triethyl groups are introduced to obtain 3% 2C6-dioxy-2- (triethyl) heptane.
    The above methods have their own advantages and disadvantages. In actual synthesis, it is necessary to carefully choose the appropriate synthesis path according to various factors such as the availability of raw materials, the difficulty of controlling reaction conditions, and the level of yield and selectivity.
    What is the price range of 3,6-dichloro-2- (trifluoromethyl) pyridine in the market?
    I am looking at your words, but I am inquiring about the price range of 3,6-dioxy-2- (triethoxy) pyridine in the market. However, this is not something I am familiar with, and the market price often varies due to factors such as quality, source, supply and demand, so it is difficult to determine its price.
    If you want to know the details, you can go to a pharmaceutical dealer or a chemical raw material trading office to ask people in the industry, who have been involved in this industry for a long time, or you can tell you a more accurate price range. Or on the online trading platform, check the price of the relevant goods, and comprehensively consider, and you can get an approximate price. But this is only a temporary price, and it cannot be determined for a long time.