3-[5-iodo-3-(trifluoromethyl)-1H-pyrazol-1-yl]pyridine

3 - [5 - iodo - 3 - (trifluoromethyl) -1H - pyrazol - 1 - yl] pyridine is an organic compound with a wide range of main application fields and important uses in medicinal chemistry, materials science, agricultural chemistry, etc.
In the field of medicinal chemistry, such compounds containing nitrogen heterocyclic structures exhibit unique biological activities. Due to their specific chemical structure, they can interact with specific targets in organisms. For example, they can be used as potential drug lead compounds for the development of anti-cancer drugs. Studies have shown that the structure containing fluoride and iodine helps to enhance the binding affinity of compounds to protein targets, thereby regulating related cell signaling pathways and inhibiting the growth and proliferation of tumor cells. In addition, in the development of antibacterial drugs, the compound may also exhibit antibacterial activity, inhibiting bacterial growth by interfering with bacterial metabolic processes or cell wall synthesis.
In the field of materials science, it can be used as a key structural unit for the construction of new functional materials. Because of its good electronic properties and thermal stability, it can be used to prepare organic Light Emitting Diode (OLED) materials. By rationally designing the molecular structure and regulating its luminescence properties, high-efficiency electroluminescence can be achieved. In addition, in the field of sensor materials, the compound's ability to selectively identify specific substances is expected to be used to develop high-sensitivity chemical sensors for the detection of environmental pollutants or biomarkers.
In the field of agricultural chemistry, 3- [5-iodo-3- (trifluoromethyl) -1H-pyrazol-1-yl] pyridine can be used as an active ingredient of new pesticides. It interferes with the nervous system or growth and development process of pests, thus exerting the effect of insecticidal and deworming. At the same time, its good chemical stability helps to maintain a long efficacy period in the natural environment, reduce the frequency of pesticide use, and reduce the negative impact on the environment.
In summary, 3 - [5 - iodo - 3 - (trifluoromethyl) -1H - pyrazol - 1 - yl] pyridine has shown great application potential in the fields of medicine, materials and agriculture. With the deepening of research, it is expected to bring more innovative results and applications to various fields.

To prepare 3- [5-iodine-3- (trifluoromethyl) -1H-pyrazole-1-yl] pyridine, there are various methods. First, the pyridine substrate can be taken first, and the trifluoromethyl-containing group can be introduced under specific reaction conditions, and then the pyrazole structure can be introduced at a suitable check point, and the 5-position iodine atom of the pyrazole structure can be introduced in a suitable reaction system with a suitable iodine substitution reagent in a subsequent step.
Second, we can start from pyrazole compounds, first construct pyrazole containing trifluoromethyl, and then connect it with pyridine fragments through a suitable coupling reaction. This coupling reaction requires careful selection of catalysts, ligands and reaction solvents to promote its efficient occurrence.
Third, we can also consider the one-pot strategy, in the same reaction system, add pyridine, pyrazole-related raw materials and various reagents in sequence, and achieve one-step synthesis of the target product through ingenious design of the reaction sequence and conditions. Although this strategy can simplify the operation process, it requires high precision control of the reaction conditions.
No matter what method is used, the reaction conditions at each step need to be investigated and optimized in detail, such as temperature, time, and the proportion of reactants, etc., and the intermediate and final products should be strictly separated, purified, and structurally characterized to ensure the purity and structural correctness of the resulting products.

3- [5-Iodine-3- (trifluoromethyl) -1H-pyrazole-1-yl] pyridine, which is an organic compound. Its physical and chemical properties are unique, and it is related to its performance in various chemical processes and applications.
Regarding the physical properties, under normal temperature and pressure, this compound may be in a solid state, but there is no detailed record of the exact melting point and boiling point. However, based on the characteristics of similar compounds containing pyrazole and pyridine structures, it can be inferred that due to the interaction of hydrogen bonds and van der Waals forces between molecules, the melting point is not expected to be too low. And its molecular structure contains iodine atoms and trifluoromethyl, which may cause the molecular polarity to change, which will affect its solubility. In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), there may be some solubility, because the polarity of these solvents matches the compound, and intermolecular forces can help it dissolve.
As for the chemical properties, both the pyridine ring and the pyrazole ring of the compound are reactive. The nitrogen atom of the pyridine ring is rich in electrons and is vulnerable to attack by electrophilic reagents, and can undergo electrophilic substitution reactions, such as halogenation, nitrification, and sulfonation. The nitrogen atom on the pyrazole ring can also participate in the reaction, and the iodine atom at the 5-position has high activity, which is prone to nucleophilic substitution reactions. It can react with many nucleophilic reagents, such as alkoxides and amines, to form new carbon-heteroatomic bonds, and then derive a variety of compounds. In addition, the strong electron-absorbing properties of trifluoromethyl will affect the electron cloud distribution of the pyridine ring and the pyrazole ring, reducing the electron cloud density of the carbon atoms connected to it, affecting the reaction activity and selectivity.
In conclusion, the physicochemical properties of 3- [5-iodine-3- (trifluoromethyl) -1H-pyrazole-1-yl] pyridine are complex, and in-depth investigation of it is of great significance in the fields of organic synthesis and medicinal chemistry.

I don't know the price range of 3- [5-iodine-3- (trifluoromethyl) -1H-pyrazole-1-yl] pyridine in the market. However, if you want to know the price of this product, you can explore it in various ways.
First, you can visit the website of the chemical reagent supplier. At present, many suppliers are exhibiting their products and prices online, logging in to their websites, searching for accurate product names, or getting quotations for this compound. Different suppliers may have quite different prices due to differences in cost, scale, and marketing strategies, so you need to read a few more to clarify their approximate range.
Second, you can consult the chemical product trading platform. Such platforms gather many sellers and are rich in resources. If you search for this product on the platform, you can observe the prices listed by different merchants, and you can refer to the evaluation and transaction records of other buyers to help judge whether the price is reasonable.
Third, if you have contacts with people in the chemical industry, such as chemists, scientific researchers, chemical reagent purchasers, etc., you may be able to obtain relevant price information from there. They often come into contact with such compounds due to their daily work needs, or know their approximate price.
However, the price of this compound may be affected by a variety of factors. The difficulty of its synthesis is a key factor. If the synthesis steps are complicated and the conditions are harsh, the cost will be high, and the price will also rise. The market supply and demand relationship also has an impact. If the demand is strong and the supply is limited, the price will rise. Furthermore, the purity has a great impact on the price. The price of high purity is much higher than that of low purity.

I found that this 3 - [5 - iodo - 3 - (trifluoromethyl) - 1H - pyrazol - 1 - yl] pyridine is an organic compound, and its synthesis is quite complex, involving multi-step organic reactions. As for the manufacturer, in today's world, many chemical reagents and fine chemical manufacturers may be involved.
In China, such as Shanghai search banner biochemical technology joint stock company, it focuses on the production and sales of chemical reagents, with a wide range of categories, or contains this compound. In addition, Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., which is quite famous in the field of organic synthesis reagents, may also be the manufacturer of this product.
Overseas, Sigma-Aldrich has a long-standing reputation in the chemical reagent industry and is very likely to provide this compound. Its product line is rich and can meet the diverse needs of global scientific research and industrial customers. Another example is Tokyo Chemical Industry Co., Ltd. (TCI), which is known for high-quality organic reagents, or produces 3- [5-iodo-3- (trifluoromethyl) -1H-pyrazol-1-yl] pyridine.
However, in order to determine the exact manufacturer, it is necessary to check the chemical product catalog, supplier website, or consult the industry veteran in order to obtain detailed and reliable information to meet the needs of scientific research and production.