3 5 Difluoropyridine
pyridine pyrrole pyrazine piperidine piperazine

3,5-difluoropyridine

    Specifications

    HS Code

    158380

    Name 3,5-difluoropyridine
    Molecular Formula C5H3F2N
    Molecular Weight 115.08
    Appearance Colorless to light yellow liquid
    Boiling Point 117 - 118 °C
    Density 1.25 g/cm³
    Flash Point 23 °C
    Solubility In Water Slightly soluble
    Logp 1.29

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    General Information
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    Frequently Asked Questions

    As a leading 3,5-difluoropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 3,5-difluoropyridine?
    3,2,5-Divinylpyridine is an important organic compound with a wide range of application fields.
    In the field of materials science, it is very useful. It can be used as a monomer to participate in the polymerization reaction, and then a polymer material with specific properties can be prepared. Because it contains vinyl, it can be additively polymerized to form a polymer with special structure and properties. For example, the prepared polymers can be applied to optical materials, because such polymers may have good optical transparency and stability; or in the field of electronic materials, to provide materials with specific electrical properties for the manufacture of electronic components.
    In the field of chemical synthesis, 3,2,5-divinylpyridine is often used as a key intermediate. With its unique molecular structure, it can participate in various organic reactions to build more complex organic compounds. For example, in transition metal-catalyzed reactions, its vinyl can undergo coupling reactions and connect with other organic molecules to expand the structure of molecules and synthesize bioactive compounds, new drug molecules or natural product analogs.
    In the field of catalysis, 3,2,5-divinylpyridine also shows some potential. Its nitrogen atom has lone pairs of electrons, which can coordinate with metal ions to form metal complexes. Such complexes may be able to be used as catalysts to catalyze organic reactions. For example, in some oxidation reactions, reduction reactions or carbon-carbon bond formation reactions, it plays a catalytic role to improve the efficiency and selectivity of the reaction.
    In addition, it also has potential applications in the field of coatings and adhesives. Introducing it into the formulation of coatings or adhesives, with the help of its polymerization properties, can improve the adhesion, hardness and durability of coatings or adhesives, so as to meet the requirements of material properties in different scenarios.
    What are the synthesis methods of 3,5-difluoropyridine?
    The synthesis of 3,5-dienyl ketones is an important topic in organic synthetic chemistry. To synthesize such compounds, the following methods are commonly used.
    One of them is the allylation reaction. This reaction uses allyl halide or allyl alcohol as raw materials and reacts with carbonyl compounds under suitable catalysts and reaction conditions. For example, under the action of alkali, allyl halide reacts with aldehyde or ketone to generate 3,5-dienyl ketones. In this process, alkali prompts allyl halide to form allyl anion, and then nucleophilic addition of carbonyl, and then dehydrates to obtain the target product.
    The second is a variant of the Wittig reaction. The classic Wittig reaction can be used to synthesize olefins, and its variant can be applied to the preparation of 3,5-dienyl ketones. The reaction of phosphorus ylide with α, β-unsaturated carbonyl compounds can cleverly construct carbon-carbon double bonds. By rationally designing the structure of the reactants, the reaction can generate 3,5-dienyl ketones. In this reaction, the preparation of phosphorus ylide is quite critical, and it is often obtained by reacting triphenylphosphine with halogenated hydrocarbons and then treating with bases.
    The third is a coupling reaction catalyzed by transition metals. Many transition metals, such as palladium and nickel, can catalyze the coupling reaction of different halogenated hydrocarbons or alkenyl halides with alkenyl borates, alkenyl tin reagents, etc. By using such reactions, different alkenyl fragments can be precisely connected to synthesize 3,5-dienyl ketones. In transition metal catalytic reactions, the choice of ligands has a great impact on the activity and selectivity of the reaction, and suitable ligands can improve the reaction efficiency and the purity of the target product.
    In addition, there are strategies based on hydroxyaldehyde condensation reactions. By controlling the reaction conditions, the aldehyde or ketone with suitable structure undergoes hydroxyaldehyde condensation to generate β-hydroxycarbonyl compounds, and then dehydration and further modification can also obtain 3,5-dienyl ketones. This process requires fine regulation of the reaction conditions to ensure that the reaction proceeds in the expected direction and can effectively avoid the occurrence of side reactions.
    What is the market outlook for 3,5-difluoropyridine?
    3,5-Diallyl has promising market prospects. In today's world, this compound has broad and important applications in many fields, because its market prospects are bright and diverse.
    First in the field of materials, 3,5-diallyl is often used for the synthesis of special performance polymer materials. The polymer built by it has excellent mechanical properties, chemical corrosion resistance and good processing properties. This material is in high demand for high-end materials such as aerospace and automotive manufacturing. Because aerospace equipment requires materials that are both expensive and expensive, and automotive parts also pursue durability and performance. 3,5-diallyl-derived materials can just meet these needs, which is the market prospect.
    Furthermore, it also has an outstanding performance in the field of chemical synthesis. 3,5-diallyl can be used as an important medium for the synthesis of specific chemical molecules. Research and development are pursuing high-efficiency and low-toxicity new technologies, and the special properties of this compound provide the possibility of enriching molecules, which helps to develop special effects for multiple diseases. With the aging of the global population and the improvement of health care, the market demand for 3,5-diallyl as an important raw material for the synthesis of chemical compounds will also increase.
    In addition, 3,5-diallyl also has a place in the industry of adhesive materials. The adhesive properties of the modified materials can provide better adhesion, wear resistance and weather resistance. Nowadays, the performance requirements of the construction industry, woodware and other industries for the adhesive properties of materials are becoming more and more stringent. This compound can meet the rising demand of the market, and it will definitely gain more market share in the field.
    However, the market prospect is good, and there are many challenges in the face. The synthesis of 3,5-diallyl keeps improving, and strives to improve the efficiency and reduce costs. And with the guarantee of high quality, the guarantee requirements of the production process are also increasing. Therefore, the 3,5-diallyl market has a bright future, but it also needs to be new and innovative in order to fully expand its market power.
    What are the precautions for storing and transporting 3,5-difluoropyridine?
    3,5-Divinylbenzene is commonly used in chemical industry. When storing and transporting, many points must be paid attention to.
    Let's talk about storage first. This substance is afraid of heat and light, so it should be placed in a cool and well-ventilated place. Due to heat, it is easy to cause its volatilization to intensify. Excessive light may also cause a chemical reaction and cause it to deteriorate. The container must be tightly sealed to prevent it from coming into contact with air. If exposed to air, it is easy to be oxidized and affect the quality. Furthermore, it should be kept away from fire and heat sources. Because of its flammability, if there is an open flame or high temperature around it, it is easy to cause a fire and endanger safety. It must also be stored separately from oxidants and acids. Contact with these substances may trigger violent chemical reactions and cause danger.
    As for transportation. Transportation vehicles must ensure that there are no leaks, no damage, and are equipped with corresponding emergency treatment equipment. During driving, the speed should not be too fast to prevent damage to the container and material leakage due to bumps and collisions. Transportation personnel must be professionally trained and familiar with its characteristics and emergency disposal methods. When transporting, you must also follow the specified route to avoid densely populated areas and traffic-congested road sections. In case of leakage, damage hazards can be reduced. When loading and unloading, the operation must be light, and it is strictly forbidden to drop and heavy pressure to avoid external forces causing the container to break and cause accidents.
    In short, when storing and transporting 3,5-divinylbenzene, from environmental conditions to operating specifications, many details cannot be ignored, so as to ensure its safety and avoid accidents.
    What are the physical and chemical properties of 3,5-difluoropyridine?
    3,5-Dienylbenzene is an organic compound with unique physical and chemical properties.
    Looking at its physical properties, under room temperature and pressure, 3,5-dienylbenzene is mostly liquid and has a special odor. Its boiling point is slightly higher than that of ordinary saturated hydrocarbons due to the influence of double bonds in the molecular structure, and the cover double bonds change the intermolecular forces. The melting point is restricted by the regularity of molecular arrangement. Due to the existence of unsaturated bonds in the structure, the molecular arrangement is difficult to reach a high degree of regularity, and the melting point is not very high. In addition, its density is slightly smaller than that of water, it often floats in the upper layer in water, and it is difficult to dissolve in water. This is because the compound is a non-polar organic substance, and water is a polar solvent, which is based on the principle of "similar miscibility".
    When it comes to chemical properties, 3,5-dienylbenzene contains double bonds and has high chemical activity. First, it can undergo an addition reaction, such as with halogen elementals (bromine, chlorine, etc.), and halogen atoms will be added to the double bond to convert the unsaturated bond into a saturated bond. This reaction is often used for qualitative detection of double bonds and organic synthesis. Second, it can participate in oxidation reactions. Under appropriate conditions, double bonds can be oxidized or form oxygenated compounds, such as aldodes, ketones, carboxylic acids, etc. This reaction can be used in organic synthesis to construct complex molecular structures. Third, 3,5-dienylbenzene can also be polymerized. Under the action of a specific catalyst, the double bonds open and connect to each other to form a polymer. This property has important applications in the field of materials science and can prepare polymer materials with special properties.
    In short, the physical and chemical properties of 3,5-dienylbenzene make it have broad application prospects in many fields such as organic synthesis and material preparation, and can provide an important material basis for the development of related fields.