3 5 Difluoropyridine 2 6 Diamine
pyridine pyrrole pyrazine piperidine piperazine

3,5-difluoropyridine-2,6-diamine

    Specifications

    HS Code

    850570

    Chemical Formula C5H5F2N3
    Molecular Weight 145.11 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point Data may vary, typically in a certain temperature range
    Boiling Point Data may vary depending on conditions
    Solubility In Water Limited solubility
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, etc.
    Pka Value Specific pKa values for amino groups
    Density Data may be available based on experimental measurements
    Stability Stable under normal conditions, but reactive with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 3,5-difluoropyridine-2,6-diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-difluoropyridine-2,6-diamine?
    3,5-Dienyl-2,6-diyne has a wide range of main uses. In the field of organic synthesis, it is a key raw material for building complex carbon skeleton structures. Due to its unique conjugated double bond and alkyne bond structure, it can participate in many types of chemical reactions, such as cyclization reactions. With suitable reaction conditions and catalysts, it can ingeniously construct multiple cyclic compounds. This is of great significance in the total synthesis of natural products and drug molecule synthesis, and can assist in the synthesis of molecular structures with specific biological activities.
    In the field of materials science, it also shows unique value. Polymer materials with special optical and electrical properties can be prepared by polymerization. Because the conjugated system can promote electron transfer, the prepared materials can be used in organic Light Emitting Diodes (OLEDs), organic solar cells and other optoelectronic devices to improve the performance and efficiency of the devices.
    In the field of supramolecular chemistry, with its rigid and linear structure characteristics, it can be used as a building block to self-assemble with other molecules through non-covalent interactions, such as hydrogen bonds 、π - π stacking, etc., to form an ordered supramolecular structure. This supramolecular structure may play a unique role in molecular recognition, catalysis, drug delivery, etc.
    In addition, in the field of chemical biology, it may be used as a probe molecule, using its special structure to interact specifically with biomolecules, so as to track and study specific molecules or biological processes in organisms, providing a powerful tool for exploring the mysteries of life. From this perspective, 3,5-dienyl-2,6-diyne plays an important role in many scientific fields and is of great significance to promote the development of related fields.
    What are the physical properties of 3,5-difluoropyridine-2,6-diamine?
    3,5-Divinylbenzene-2,6-dialdehyde is an organic compound with special physical properties. Although it is not specifically mentioned in the traditional process involved in "Tiangong Kaiwu", it is inferred from the way of understanding and description of substances in ancient times, or has the following characteristics.
    This substance may be solid at room temperature, and many analogs containing benzene rings and aldehyde groups are mostly solid. Its melting point exists due to intermolecular forces, or is within a certain range. The phenyl ring in the molecule forms a conjugated system with vinyl and aldehyde groups, causing it to absorb specific wavelengths of light, and its appearance may have a certain color, such as yellowish.
    Furthermore, its solubility may have characteristics. The benzene ring is a hydrophobic group, and the aldehyde group has a certain polarity, which may not be very soluble in water. In some organic solvents such as ethanol and ether, it may have a certain solubility due to the principle of similar miscibility.
    In terms of volatility, although the benzene ring structure is relatively stable, the aldehyde group activity is high, and the vinyl group increases the molecular unsaturation, or makes the compound volatile to a certain extent. It can smell a special smell in the air, but due to the presence of the benzene ring, the volatility is not extremely strong. In addition, because it contains polyunsaturated bonds and aldehyde groups, it is chemically active and prone to reactions such as addition and oxidation. Although this is not strictly physical, it is related to physical properties. Active chemical properties may affect its physical state stability in different environments.
    Is the chemical property of 3,5-difluoropyridine-2,6-diamine stable?
    The chemical properties of 3,5-diallyl-2,6-diacetyl are quite stable. In the structure of this compound, the presence of allyl and acetyl groups gives it unique properties. Allyl has a certain reactivity, but in this compound, its activity is regulated due to its interaction with surrounding groups.
    From the perspective of spatial structure, each group affects each other to build a relatively stable structural system. The electron-absorbing effect of acetyl groups will affect the electron cloud distribution of allyl groups, reducing the electron cloud density of allyl groups, which in turn leads to a decrease in their nucleophilic reactivity.
    At the same time, the conjugation effect within the molecule also contributes to its stability. The π bond of the allyl group forms a conjugated system with the carbonyl group of the acetyl group, and the electrons can be delocalized in the conjugated system, which reduces the molecular energy and improves the stability.
    Furthermore, the physical properties of the compound also contribute to its stability. It has a certain solubility and melting point, and can maintain a relatively stable state in common organic solvents. It is not easy to decompose or other chemical reactions due to minor changes in the external environment.
    In summary, 3,5-diallyl-2,6-diacetyl exhibits relatively stable chemical properties due to its own structural characteristics, electronic effects and physical properties.
    What are the synthesis methods of 3,5-difluoropyridine-2,6-diamine?
    The synthesis method of 3,5-dienyl-2,6-diyne is very ingenious. I will describe it in detail for you.
    First, it can be obtained by the coupling reaction of halogenated olefins with alkynyl-based reagents. Halogenated olefins have active halogen atoms. When encountering alkynyl-based metal reagents, such as alkynyl-based lithium or alkynyl-based copper reagents, under suitable reaction conditions, the halogen atoms leave and couple with the alkynyl group to form a carbon-carbon bond, thus forming a skeleton of 3,5-dienyl-2,6-diyne. This reaction requires precise control of the reaction temperature, solvent and catalyst. Too high or too low temperature can affect the reaction rate and product selectivity; suitable solvents, such as ether or aromatic hydrocarbon solvents, can provide a good environment for the reaction; and catalysts, such as palladium-based catalysts, can significantly improve the reaction efficiency.
    Second, a multi-step reaction strategy is adopted. First, an intermediate containing alkenyl and alkynyl groups is prepared from suitable raw materials, and then the target structure is constructed by intramolecular cyclization. For example, an organic compound containing multiple functional groups is used as a starting material, and the alkenyl and alkynyl groups are gradually introduced through esterification, halogenation, nucleophilic substitution, etc., and finally cyclization occurs under specific conditions to generate 3,5-dienyl-2,6-diyne. Although this strategy is cumbersome, it can flexibly adjust the reaction path to improve the purity and yield of the product.
    Third, the tandem reaction catalyzed by transition metals. Transition metals such as nickel and palladium can activate multiple chemical bonds at the same time, so that the reaction can proceed continuously. Under the action of transition metals, the raw material molecules undergo addition, elimination, coupling and other reactions in sequence, and a complex 3,5-dienyl-2,6-diyne structure is constructed in one step. This method has high atomic economy and simple reaction steps, but it requires strict reaction conditions and catalysts.
    There are many methods for synthesizing 3,5-dienyl-2,6-diyne, each with its advantages and disadvantages. It is necessary to weigh factors such as raw material cost, reaction conditions, product purity and yield according to actual needs, and choose the optimal method to successfully prepare this compound.
    What is the market price of 3,5-difluoropyridine-2,6-diamine?
    In the market, the price of 3% 2C5-divinylbenzene-2% 2C6-dibromine often varies greatly due to factors such as quality, origin, supply and demand.
    Looking at the market, if the quality is high, it comes from a famous place of origin, and the market demand exceeds the supply at that time, the price will be high. On the contrary, if the quality is average, the origin is ordinary, and the market supply is sufficient, the price will be lower.
    In today's world, the price of these two substances fluctuates roughly between [X1] and [X2] gold per kilogram. However, this is only an approximate number, not an exact value. Due to the turbulence and rapid change of the chemical market, the fluctuation of raw material prices, the improvement of manufacturing processes, and the adjustment of tariff policies can all make its prices fluctuate up and down.
    Therefore, in order to know its accurate price, it is necessary to constantly observe the dynamics of the chemical market, consult industry merchants, or check professional chemical price information platforms, in order to obtain the current exact price, so as to avoid trading errors due to unknown prices.