3 5 Dichloro 2 Fluoropyridine
pyridine pyrrole pyrazine piperidine piperazine

3,5-Dichloro-2-fluoropyridine

    Specifications

    HS Code

    234824

    Chemical Formula C5H2Cl2FN
    Molecular Weight 166.0
    Appearance A colorless to light yellow liquid or solid
    Boiling Point Around 195 - 197 °C
    Melting Point Approximately 15 - 17 °C
    Density Data unavailable
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Data unavailable
    Vapor Pressure Data unavailable

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    General Information
    Where to Buy 3,5-Dichloro-2-fluoropyridine in China?
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    Frequently Asked Questions

    As a leading 3,5-Dichloro-2-fluoropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-dichloro-2-fluoropyridine?
    3,5-Dioxo-2-pentenone has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. The special unsaturated lactone structure in its structure gives it active reactivity, which can participate in multiple organic reactions and help synthesize other complex organic compounds.
    It plays an important role in the field of medicinal chemistry. By participating in a series of reactions, compounds with specific biological activities can be prepared, which is of great significance for the development of new drugs. For example, some drug molecules with antibacterial, anti-inflammatory or anti-tumor activities have 3,5-dioxo-2-pentenone in their synthesis process.
    In the field of materials science, there are also applications. Due to its unique chemical properties, polymer materials can be introduced through specific reactions to improve the properties of materials, such as enhancing the stability, mechanical properties or endowing special functions of materials, providing new paths for the development of high-performance materials.
    In addition, in the field of fragrance chemistry, 3,5-dioxy-2-pentenone may participate in the synthesis of compounds with unique aromas, injecting new flavors into fragrance formulation and enriching fragrance categories. In short, 3,5-dioxy-2-pentenone, with its various uses, plays an important role in many fields and promotes the development and progress of various fields.
    What are the synthesis methods of 3,5-dichloro-2-fluoropyridine?
    The synthesis method of 3,5-dihydroxy-2-pentenone is a very important topic in the field of organic synthesis. The following are common synthesis methods:
    First, the synthesis method using ethyl acetoacetate as the starting material. Ethyl acetoacetate undergoes nucleophilic substitution reaction with halogenated hydrocarbons under basic conditions to generate the corresponding substituted ethyl acetoacetate. After hydrolysis and decarboxylation, the target product can be obtained. This process requires precise control of the reaction conditions. The strength of alkalinity, reaction temperature and time all have a great impact on the yield and purity of the product. For example, too much alkalinity may lead to side reactions and reduce the purity of the product; improper reaction temperature may cause the reaction rate to be too slow or cause overreaction.
    Second, by the synthesis of diethyl malonate. Diethyl malonate first interacts with a base to generate a carbon negative ion, which reacts with a suitable electrophilic reagent to form a carbon-carbon bond. Then, through hydrolysis, decarboxylation and other steps, it is gradually directed to 3,5-dihydroxy-2-pentenone. In this path, the choice of electrophilic reagents is crucial, and its structure and activity are directly related to the selectivity of the reaction and the structure of the product.
    Third, the microbial synthesis method is adopted. Some microorganisms have specific enzyme systems that can catalyze the conversion of specific substrates to 3,5-dihydroxy-2-pentenone. This method has the advantages of mild reaction conditions and environmental friendliness. However, the microbial culture conditions are harsh, and factors such as temperature, pH value, and nutrient concentration need to be precisely controlled to maintain the activity of microorganisms and the normal operation of metabolic pathways.
    Fourth, chemical enzymatic synthesis. Combining the advantages of chemical synthesis and enzyme catalysis, the key intermediates are first synthesized by chemical methods, and then the high-efficiency catalysis and high selectivity of enzymes are used to complete the subsequent reaction to generate the target product. This method can avoid some cumbersome steps and low selectivity problems in traditional chemical synthesis, and at the same time overcome the shortcomings of limited substrate range in biosynthesis.
    All synthetic methods have their own advantages and disadvantages. In practical application, the appropriate synthetic method should be selected according to specific requirements, such as product purity, cost, yield and other factors.
    What is the market price of 3,5-dichloro-2-fluoropyridine?
    I think what you are asking is about the market price of 3,5-dihydro-2-furanaldehyde. However, the price of this product often varies due to various factors such as time and place, supply and demand, and quality, so it is difficult to give an exact price.
    In the chemical market, if the supply and demand balance, the price may stabilize; if the supply exceeds the demand, the price may decrease; if the demand exceeds the supply, the price will rise. And in different places, due to different transportation costs and tax policies, the price is also different. The quality affects the price even more. High quality is expensive, and low quality is cheap.
    If you want to know the detailed price today, you can consult the chemical raw material supplier, where you can often get the latest and most accurate price. Or refer to the chemical product trading platform to observe the recent transaction price to understand the market situation. In addition, it is also a good way to communicate with industry insiders to explore market trends. In short, to obtain the exact market price of 3,5-dihydro-2-furanaldehyde, you need to explore many ways and consider comprehensively to obtain it.
    What are the physical and chemical properties of 3,5-dichloro-2-fluoropyridine?
    3,5-Difluoro-2-fluoroethoxylbenzene is an organic compound. In the era of "Tiangongkai", there was no such thing. However, with today's knowledge, its physicochemical properties are described as follows:
    This substance may be a colorless transparent to light yellow liquid at room temperature, with a special odor, its odor or irritation, or weak. Its physical constants such as boiling point and melting point have unique manifestations due to the presence of fluorine atoms and ethoxy groups in the structure. Fluorine atoms have high electronegativity, which changes the force between molecules, causing the boiling point to be different from that of ordinary benzene series. Its melting point or due to the influence of molecular structure regularity and polarity, is in a specific numerical range, which can be accurately determined by modern instruments.
    In terms of chemical properties, benzene rings are aromatic and can undergo electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. Due to the localization effect of fluorine atoms and ethoxy groups, the substitution reaction check point may be selective. The density of electron clouds in the adjacent and para-position of fluorine atoms changes, making it easier for electrophilic reagents to attack specific positions. Oxygen atoms in ethoxy groups have solitary pair electrons, which have electron-supplying conjugation effects on the electron cloud of the benzene ring, which also affect the reactivity and selectivity.
    At the same time, fluorine atoms in this compound can participate in the formation of weak interactions such as hydrogen bonds, which affect their solubility and aggregate state structure. In organic solvents, or due to interactions with solvent molecules, it exhibits good solubility; in water, due to polar differences, solubility These are all important physicochemical properties of 3,5-difluoro-2-fluoroethoxylbenzene, which play an important role in the fields of organic synthesis and materials science.
    What are the precautions for storing and transporting 3,5-dichloro-2-fluoropyridine?
    3,5-Difluoro-2-fluoroethoxybenzene requires attention to many matters during storage and transportation.
    For storage, due to its specific chemical properties, it should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources, and prevent direct sunlight, otherwise it may cause changes in material properties, or even cause dangerous conditions. It should be stored separately from oxidants, acids, alkalis, etc., to avoid mixed storage to prevent chemical reactions. The storage area should be equipped with suitable materials to contain leaks. In case of leaks, it can be dealt with in time to reduce hazards.
    In terms of transportation, ensure that the transportation vehicle is in good condition and has the necessary safety facilities. During transportation, it needs to be tightly covered to prevent rain and moisture. Drivers and escorts should be familiar with the characteristics of the substance and emergency treatment methods, and regularly check the status of the goods on the way. Follow the specified route and stay away from densely populated areas and important facilities to reduce transportation risks. Be careful when loading and unloading to avoid collisions and falls to prevent leakage due to damaged packaging. In the event of a leak, the emergency plan should be activated immediately, the surrounding personnel should be evacuated, and corresponding leak plugging and cleaning measures should be taken.