3 5 Dibromo 2 Hydroxy 6 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

3,5-Dibromo-2-hydroxy-6-methylpyridine

    Specifications

    HS Code

    745650

    Chemical Formula C6H5Br2NO
    Molar Mass 266.918 g/mol
    Appearance Solid (usually a white - off - white powder)
    Melting Point 138 - 142 °C (reported range)
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Pka Related to the acidic nature of the hydroxyl group, approximate value around 8 - 10
    Vapor Pressure Very low at room temperature
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
    Where to Buy 3,5-Dibromo-2-hydroxy-6-methylpyridine in China?
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    Frequently Asked Questions

    As a leading 3,5-Dibromo-2-hydroxy-6-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3,5-dibromo-2-hydroxy-6-methylpyridine?
    3,5-Dibromo-2-fluoro-6-methylpyridine is a crucial intermediate in organic synthesis. It is particularly widely used in the field of medicinal chemistry and can be used as a key starting material for the preparation of various drugs. For example, in the synthesis process of some antimicrobial and antiviral drugs with specific biological activities, 3,5-dibromo-2-fluoro-6-methylpyridine can introduce the required functional groups through specific chemical reactions, gradually build the skeleton of drug molecules, and then achieve the synthesis of target drugs.
    In the field of pesticide chemistry, this compound has also shown important value. It can be used as a key intermediate in the preparation of new pesticides. By reacting with other reagents, pesticide products with high insecticidal, bactericidal or herbicidal properties can be created. For example, pesticides with high selectivity, low toxicity and environmental friendliness to specific crop pests can be designed and synthesized to effectively protect the growth of crops and improve the yield and quality of crops.
    In the field of materials science, 3,5-dibromo-2-fluoro-6-methylpyridine can be used to prepare functional organic materials. Through ingenious modification and polymerization, it can be integrated into the structure of polymer materials, endowing the materials with unique properties such as special optical and electrical properties, so as to meet the needs of high-performance materials in fields such as organic Light Emitting Diode (OLED) and organic solar cells. In short, 3,5-dibromo-2-fluoro-6-methylpyridine has indispensable uses in many fields due to its unique structure, promoting scientific research and industrial development in related fields.
    What are the synthesis methods of 3,5-dibromo-2-hydroxy-6-methylpyridine?
    To prepare 3% 2C5-dibromo-2-fluoro-6-methylpyridine, there are various methods.
    First, it can be started from the parent pyridine. First, an appropriate methylation reagent, such as iodomethane, works synergistically with a base to introduce methyl into the 6th position of the pyridine ring to obtain 6-methylpyridine. Then, select a suitable fluorination reagent, such as Selectfluor, etc., under specific conditions, fluoride the 2nd position to obtain 2-fluoro-6-methylpyridine. Finally, bromine atoms are introduced at positions 3 and 5 with brominating reagents, such as liquid bromine, under the catalysis of catalysts (such as iron powder, etc.), and the target product is 3% 2C5-dibromo-2-fluoro-6-methylpyridine.
    Second, it can also be started from fluorine-containing pyridine derivatives. If there is a suitable fluorine-containing pyridine, it is first methylated and modified, and methyl is added at position 6. After that, bromine atoms are introduced at positions 3 and 5 precisely by means of bromination, which can also achieve the purpose of preparation.
    Third, the strategy of constructing pyridine rings can also be used. Under suitable reaction conditions, the pyridine ring is formed by cyclization reaction with suitable precursor compounds containing fluorine, methyl and bromine atoms, and 3% 2C5-dibromo-2-fluoryl-6-methyl pyridine is directly generated. This strategy requires fine regulation of the structure and reaction conditions of the precursor compound to obtain the product with ideal yield and purity.
    All kinds of synthesis methods have their own advantages and disadvantages. The availability of starting materials, the difficulty of reaction conditions, and the separation and purification of the product are all factors to be considered. In practice, the optimal method should be selected according to the specific situation to obtain the target product efficiently.
    What are the physical properties of 3,5-dibromo-2-hydroxy-6-methylpyridine?
    3,5-Dibromo-2-fluoro-6-methylpyridine is an organic compound with unique physical properties. It is usually solid at room temperature and has a relatively high melting point due to strong intermolecular forces. From the appearance point of view, it may be white to light yellow crystalline powder, this color may be slightly different due to the presence of impurities or crystal form differences.
    When it comes to solubility, this compound has good solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc. Because it is an organic molecule, it follows the principle of similar miscibility, and can form a moderate intermolecular force with organic solvent molecules, so it can be well miscible. However, its solubility in water is poor, due to its relatively weak molecular polarity, it is difficult to form strong interactions with water molecules, so it is not easily soluble in water.
    The density of 3,5-dibromo-2-fluoro-6-methylpyridine also has a specific range, and the specific value depends on the precise determination conditions. Generally speaking, its density is higher than that of water. In the field of organic synthesis, this property is of great significance in the separation and purification process. With the help of density differences, it can be initially separated from other substances by means such as extraction and stratification.
    Furthermore, the stability of this compound is worthy of attention. Under normal conditions, it is relatively stable, but when exposed to extreme conditions such as high temperature, strong oxidants or strong bases, the molecular structure may change. Because its molecules contain halogen atoms such as bromine and fluorine, as well as functional groups such as methyl groups, these functional groups can undergo chemical reactions under specific conditions, such as halogen atoms can participate in nucleophilic substitution reactions, and methyl groups can undergo oxidation and other reactions, which can be used in organic synthesis to construct more complex organic molecular structures.
    What are the precautions for storing and transporting 3,5-dibromo-2-hydroxy-6-methylpyridine?
    3% 2C5-dibromo-2-fluoro-6-methylpyridine This compound has many things to pay attention to when storing and transporting.
    The first storage link, because of its specific chemical activity, must choose a dry, cool and well-ventilated place. Humid environment is prone to chemical reactions such as hydrolysis, which damage the purity and quality of the material. If the ambient humidity is high, the moisture may react with the active parts of the compound and change its chemical structure. Temperature is also critical. High temperature may cause it to evaporate and accelerate, or even cause decomposition. And the compound may be toxic and corrosive, so be sure to keep it away from food, beverages and daily necessities to prevent accidental ingestion or contact with human harm. At the same time, it should be stored separately from oxidizing agents, reducing agents, etc. Due to mixed storage or triggering violent chemical reactions, it will cause danger.
    When transporting, the packaging must be solid and tight. Choose suitable packaging materials to ensure that the packaging is not damaged and leaked during transportation bumps. If the container is not selected properly, the compound will not only pollute the environment, but also endanger the safety of transporters. During transportation, the temperature should be strictly controlled, and the prescribed route should be followed to avoid densely populated areas and environmentally sensitive areas. Transporters also need professional training, familiar with the characteristics of the compound and emergency treatment methods. In the event of an accident, they can respond quickly and effectively to reduce hazards. In conclusion, whether storing or transporting 3% 2C5-dibromo-2-fluoro-6-methylpyridine, it is necessary to operate in strict accordance with regulations to ensure the safety of personnel and the environment in an all-round way.
    What is the market price of 3,5-dibromo-2-hydroxy-6-methylpyridine?
    Wen Jun inquired about the market price of "3,5-dibromo-2-fluoryl-6-methylpyridine". This product is in the market, and its price varies according to quality, quantity and source. If it is of ordinary quality and the quantity is not huge, the market price is about tens of gold to hundreds of gold per gram. If you need high purity and the quantity is quite large, the price should be high. Cover the refining process, it takes material resources and manpower, resulting in an increase in its cost, and the price also rises.
    Also, if you buy it in different places, its price is also different. In the bustling city of the city, merchants gather, competing to sell this product, or the price is slightly lower due to competition for profit; in the remote territory, there are few sources of supply, and its price is high. And times change, the market conditions change, and its price may also change. Therefore, if you want to know the exact price, you must consult all pharmaceutical shops and chemical companies in detail, and depending on the current market situation, you can get the actual price.