As a leading 3,5-DibroMo-2-fluoro-6-Methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 3,5-dibromo-2-fluoro-6-methylpyridine?
3,5-Dibromo-2-pentene-6-methylpyridine is an important organic compound with key uses in many fields.
In the field of organic synthesis, it often acts as a key intermediate. With its unique structure, it can be skillfully combined with other compounds through various chemical reactions, such as nucleophilic substitution, addition, etc., to construct organic molecules with more complex structures and unique functions. For example, in pharmaceutical chemistry, it can be used to synthesize drug molecules with specific biological activities. Due to the fact that bromine atoms, double bonds, and pyridine rings in its structure can all participate in the reaction, it provides rich possibilities for the synthesis of novel drugs, helping chemists to develop drugs with more curative effects and lower side effects.
In the field of materials science, this compound has also emerged. Because it contains conjugated structures and specific functional groups, it may endow materials with unique electrical and optical properties. For example, the preparation of organic semiconductor materials may improve the charge transport performance of materials, thereby enhancing the performance of organic electronic devices such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs), etc., so that the performance of related displays and electronic devices can be better.
At the level of scientific research and exploration, 3,5-dibromo-2-pentene-6-methylpyridine provides a key tool for chemical research. Researchers can further clarify the reaction mechanism of organic chemistry by in-depth exploration of its reactivity and structural properties, expand the theoretical understanding of organic chemistry, and lay the foundation for the development of new reaction and synthesis methods.
What are the physical properties of 3,5-dibromo-2-fluoro-6-methylpyridine?
3% 2C5-dibromo-2-pentene-6-methylpyridine is an organic compound with special physical properties. The investigation of its properties is of great significance in the fields of organic synthesis and medicinal chemistry. Its physical properties are as follows:
1. ** Appearance and properties **: At room temperature and pressure, it is mostly colorless to light yellow liquid, and the pure one is clear and transparent. This appearance property is affected by the arrangement and interaction of atoms in the molecular structure. Because the molecule contains unsaturated double bonds and atoms such as bromine and nitrogen, the distribution of electron clouds is uneven, and it has a unique performance of light absorption and scattering, showing specific colors and transparency.
2. ** Boiling point and melting point **: The boiling point is about 240 - 250 ° C, and the melting point is about - 20 - - 15 ° C. The boiling point is higher, due to the existence of various forces between molecules, such as van der Waals force and dipole-dipole interaction. Unsaturated double bonds and polar groups enhance the attraction between molecules, requiring more energy to overcome, so the boiling point is high. The melting point is relatively low. Due to the shape and arrangement of molecules not reaching a close order, the lattice energy is limited, and the molecules still have a certain degree of freedom of movement at low temperatures.
3. ** Solubility **: Slightly soluble in water, soluble in common organic solvents, such as ethanol, ether, chloroform, etc. Due to the hydrophobic hydrocarbon skeleton in the molecule, it is difficult to form an effective interaction with polar water molecules, so it is insoluble in water. The organic solvent and the compound molecule can form a similar intermolecular force, which satisfies the principle of "similar miscibility" and realizes mutual dissolution.
4. ** Density **: The density is about 1.4-1.5 g/cm ³, which is larger than water. Because the bromine atom in the molecule has a large relative atomic mass and occupies a certain space, the unit volume mass increases, and the density is higher than that of water.
5. ** Odor **: It has a special irritating odor, which originates from the structure of bromine atom and pyridine ring in the molecule. The bromine atom has high activity and the pyridine ring has a special electronic structure. The two cooperate to make the odor unique and irritating, so it
What is the chemical synthesis method of 3,5-dibromo-2-fluoro-6-methylpyridine?
To prepare 3,5-dibromo-2-pentene-6-methylpyridine, the chemical synthesis method is as follows:
First, a suitable pyridine derivative is used as the starting material. A pyridine with a suitable substituent can be selected first, and methyl groups can be introduced through alkylation reaction. In this step, a halogenated methane with suitable activity needs to be selected, and a strong base is used as a catalyst in a suitable organic solvent to control the temperature. The methyl group is precisely connected to the 6th position of the pyridine ring.
The alkylation reaction is carried out for the first time. Using the Wittig reaction or similar reactions, a phosphorus-containing Ylide reagent is reacted with a suitable carbonyl compound to form a carbon-carbon double bond under mild conditions to construct a 2-pentene structure. This step requires fine regulation of the reaction conditions to ensure the accuracy of the configuration and position of the double bond.
Furthermore, a bromination reaction is performed. At low temperatures, the reaction system is added dropwise to a solution containing a bromine reagent. Bromine or N-bromosuccinimide (NBS) is commonly used to initiate the reaction with light or an initiator, so that the bromine atom is selectively grafted to the 3,5 position. Among them, the polarity of the solvent, the reaction temperature and time all have a great influence on the regioselectivity of bromination and must be carefully controlled.
After each step of the reaction, the product needs to be purified by column chromatography, recrystallization, etc. to remove impurities and maintain the purity of the product. After various steps of reaction and purification, the target product 3,5-dibromo-2-pentene-6-methylpyridine can be obtained. The whole process of synthesis requires strict adherence to chemical operating standards, experimental safety, and precise control of reaction conditions to achieve ideal yield and purity.
What are the precautions for storing and transporting 3,5-dibromo-2-fluoro-6-methylpyridine?
During the storage and transportation of 3,5-dibromo-2-pentene-6-methylbenzene, many things need to be paid attention to.
First, in terms of storage, because of its nature may be lively, it must be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources and prevent direct sunlight, otherwise it is easy to cause chemical reactions or risk safety due to excessive temperature. It needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. It may react violently with these substances and cause danger. The storage area should be equipped with suitable containment materials so that in the event of leakage, it can be handled in time to avoid its spread and cause greater harm.
Second, when transporting, ensure that the container is well sealed to prevent leakage during transportation. The transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. During driving, it is necessary to stay away from densely populated areas and dangerous areas such as fire sources, and the transporters must have the corresponding chemical dangerous goods transportation qualifications and knowledge, and be familiar with emergency treatment methods. During transportation, it is necessary to regularly check the status of the goods. If the packaging is found to be damaged or there are signs of leakage, effective measures should be taken immediately, such as transferring to a safe place and plugging treatment. At the same time, it is necessary to strictly abide by the relevant transportation regulations, drive according to the designated route, and do not change the route at will to ensure the safety of the transportation process.
What are the effects of 3,5-dibromo-2-fluoro-6-methylpyridine on the environment and human health?
3,5-Dibromo-2-pentene-6-methylbenzene, this is an organic compound, which does have an impact on the environment and human health, as detailed below:
###Effects on the environment
1. ** Aquatic organisms **: Most of these organic halides are toxic. If they flow into water bodies through industrial wastewater or other channels, they are easy to accumulate in aquatic organisms. If fish ingest water containing this compound, it may affect their normal physiological functions, causing growth and development to be hindered, or even mortality to increase. And biological enrichment will be transmitted along the food chain, posing a potential threat to higher trophic organisms.
2. ** Soil ecology **: If it enters the soil, or changes the structure and function of the soil microbial community. Because microorganisms are essential for material circulation and nutrient transformation in the soil, the microbial community is affected, or the soil fertility is reduced, affecting plant growth and disturbing the balance of the entire ecosystem.
3. ** Atmospheric environment **: Although it is volatile or limited at room temperature, it participates in photochemical reactions under specific conditions such as high temperature, combustion process, or volatilization into the atmosphere, generating secondary pollutants, affecting air quality, and forming hazards such as chemical smog.
###Effects on human health
1. ** Nervous system **: Organic halide is often neurotoxic. Human exposure to this compound may interfere with the normal function of the nervous system. Early or present symptoms such as headache, dizziness, fatigue, long-term exposure, or damage to nerve cells, resulting in memory loss, cognitive impairment, or even cause more serious neurological diseases.
2. ** Reproductive system **: Studies have shown that many organic halides can interfere with the human endocrine system. For the reproductive system, it may affect the balance of hormones and cause damage to reproductive function. Men or present with reduced sperm count and reduced vitality; women or present with problems such as menstrual disorders, difficulty conceiving, and may have adverse effects on fetal development, increasing the risk of birth defects.
3. ** Cancer risk **: Some halogenated organic compounds have been proven to be carcinogenic. Long-term exposure to 3,5-dibromo-2-pentene-6-methylbenzene may increase the risk of cancer, such as liver cancer, lung cancer, etc., because it may cause cell gene mutations, causing normal cells to multiply abnormally and then develop into cancer cells.