3 5 Dibromo 2 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

3,5-Dibromo-2-chloropyridine

    Specifications

    HS Code

    534605

    Chemical Formula C5H2Br2ClN
    Molecular Weight 272.34
    Appearance Solid (usually a white to off - white powder)
    Melting Point Typically in the range of 85 - 90 °C (approximate, can vary based on purity)
    Boiling Point Data may be limited, but it decomposes before boiling due to its relatively high reactivity
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, and ethyl acetate
    Odor May have a faint, characteristic halogen - containing organic odor
    Density Estimated density around 2.1 - 2.3 g/cm³ (approximate, calculated from structure and related compounds)

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    Frequently Asked Questions

    As a leading 3,5-Dibromo-2-chloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3,5-dibromo-2-chloropyridine?
    3,2,5-Dibromo-2-pentene is an organic compound with unique chemical properties.
    In terms of chemical activity, the bromine atom in this molecule is active. As a halogen element, the bromine atom is highly electronegative, resulting in the polarity of the C-Br bond. In many chemical reactions, this polar bond is susceptible to attack by nucleophiles, which in turn triggers nucleophilic substitution reactions. For example, when co-heated with an alcohol solution of sodium hydroxide, an elimination reaction occurs, and the bromine atom is removed in the form of hydrogen bromide along with the hydrogen atom on its adjacent carbon atom to form an unsaturated hydrocarbon containing a carbon-carbon double bond.
    From the perspective of addition reaction characteristics, the compound molecule contains carbon-carbon double bonds, which can undergo addition reactions with many electrophilic reagents. In case of bromine water, the carbon-carbon double bond can be added to the bromine molecule, causing the bromine water to fade. This is due to the high density of the carbon-carbon double bond electron cloud, which is vulnerable to electrophilic attack. The bromine molecule is polarized under the action of the double bond electron cloud, and then adds to the double bond to form a new dibromo product.
    Once again discussing its stereochemical properties, the 2-pentene structure causes the compound to exist cis-trans isomers. Different spatial configurations have effects on its physical and chemical properties. In some reactions, steric hindrance factors can cause differences in reaction rates and product selectivity due to different isomers.
    In the field of organic synthesis, 3,2,5-dibromo-2-pentene is often used as a key intermediate. Due to its active bromine atom and double bond, it can construct complex organic molecular structures through various reactions, providing an effective path for the synthesis of organic compounds with specific functions and structures.
    What are the common synthesis methods of 3,5-dibromo-2-chloropyridine?
    3,5-Dibromo-2-nitrotoluene is an important intermediate in organic synthesis. The common synthesis methods are as follows:
    First, toluene is used as the starting material. First, toluene is nitrified under the action of concentrated sulfuric acid and concentrated nitric acid to form a mixture of o-nitrotoluene and p-nitrotoluene. After separation, o-nitrotoluene is obtained. Then o-nitrotoluene is brominated with bromine in the presence of catalysts such as iron bromide, and bromine atoms are introduced into the adjacent and para-methyl sites to obtain 3-bromo-2-nitrotoluene and 5-bromo-2-nitrotoluene. After careful separation, 3,5-dibromo-2-nitrotoluene can be obtained. The starting material toluene is easily available in this way, but there are many reaction steps and the separation process is also complicated.
    Second, 2-nitrobenzoic acid is used as the starting material. First, 2-nitrobenzoic acid is converted into 2-nitrobenzyl alcohol through reduction reaction, and then 2-nitrobenzyl alcohol is reacted with hydrobromic acid and other reagents, and the hydroxyl group is replaced by bromine atoms. Then the product is decarboxylated to produce 3,5-dibromo-2-nitrotoluene. The reaction conditions of this path are relatively mild, but the starting material 2-nitrobenzoic acid may be more expensive.
    Third, m-dibromobenzene is used as the raw material. 3,5-dibromo-2-nitrotoluene is synthesized by nitration reaction of m-dibromobenzene with mixed acid of nitric acid and sulfuric acid, and nitro group is directly introduced at a specific position in the benzene ring. This method is a short step, but the price of m-dibromobenzene is usually higher, and the regioselective control of nitration reaction may be difficult.
    When synthesizing 3,5-dibromo-2-nitrotoluene, the most suitable synthesis method should be selected according to the actual situation, such as raw material cost, reaction conditions, yield and product purity.
    What are the main applications of 3,5-dibromo-2-chloropyridine?
    3,5-Dibromo-2-hydroxybenzaldehyde is widely used. In the field of medicine, it can be used as a key intermediate to synthesize drugs with specific biological activities. For example, in the synthesis of antibacterial drugs, with its special chemical structure, it can cleverly react with other compounds to construct molecular structures with antibacterial effects, contributing an important force to the research and development of medicine.
    In the field of materials science, it can participate in the preparation of functional materials. Like the synthesis of some organic optoelectronic materials, 3,5-dibromo-2-hydroxybenzaldehyde can be used as a starting material. After a series of reactions, it endows the material with unique optoelectronic properties, such as good fluorescence characteristics or charge transport ability, etc., and shows application potential in optoelectronic display, optoelectronic devices, etc.
    In the field of organic synthesis, it is an important reagent commonly used. Because it contains active functional groups such as aldehyde and hydroxyl groups, it can construct complex and diverse organic compounds through a variety of organic reactions, such as condensation reactions, oxidation-reduction reactions, etc., providing a rich material basis and reaction path for the development of organic synthetic chemistry, helping chemists to create more novel and functional organic molecules.
    What is the market price of 3,5-dibromo-2-chloropyridine?
    Today, there is 3% 2C5-dibromo-2-pentene, and its market price is determined due to general factors.
    First, the situation of this material is different. If it is a rich source, it is easy to gather and improve the land, and it is cheap; if it is a remote place, where there is a lack of sources, it will be high.
    Second, the supply and demand of the market will be low, and the price will be high. If the demand is low, and the quantity is small, the "material will be thin", and the price will rise; on the contrary, if the supply is high and the demand is low, the merchant will sell it, or reduce it to sell.
    Third, it is also left and right. The method of refinement can increase efficiency and reduce its cost, and it is also lower than the cost. If the technology is good, the cost is high, and the price is low.
    Fourth, the transformation of the market and the direction of policy have all had an impact. The weight of the problem and the system of protection do not reduce the cost of production, which affects the price.
    Therefore, in order to know the market of 3% 2C5-dibromo-2-pentene, it is necessary to observe the factors of land, supply and demand, technology and policy. However, the current situation is not the same, so I can say some of them bluntly.
    What are the storage conditions for 3,5-dibromo-2-chloropyridine?
    The storage conditions of 3,2,5-dibromo-2-pentene are as follows:
    This compound should be stored in a cool and well-ventilated place. Because of its certain chemical activity, it is more sensitive to temperature. Excessive temperature may cause chemical reactions, so it is necessary to keep away from fire and heat sources. The storage temperature should not exceed 30 ° C.
    At the same time, it should be stored separately from oxidants and food chemicals, and mixed storage should not be avoided. Due to its chemical properties, contact with oxidants may cause severe reactions, endangering storage safety; mixed storage with food chemicals may cause pollution due to unexpected conditions such as leakage, causing serious consequences.
    Storage sites should be equipped with suitable materials to contain leaks. Because if the substance leaks, it needs to be properly handled in a timely manner to prevent harm to the environment and personnel. In the storage area, obvious safety warning signs should be set up to remind staff to pay attention to its danger. The handling process must be handled lightly to prevent damage to the packaging and containers, and to avoid leakage of the substance due to improper operation.
    During the storage process, it is also necessary to regularly check the storage status to check whether the packaging is in good condition and whether there are signs of leakage, etc., to ensure that the storage environment is stable to ensure the storage safety of the chemical substance.