3 4 Bromophenyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

3-(4-Bromophenyl)pyridine

    Specifications

    HS Code

    789226

    Name 3-(4-Bromophenyl)pyridine
    Molecular Formula C11H8BrN
    Molecular Weight 234.09
    Appearance Solid
    Color Off - white to light yellow
    Boiling Point 327.5°C at 760 mmHg
    Melting Point 87 - 91°C
    Density 1.435 g/cm³
    Flash Point 152.9°C
    Solubility Soluble in organic solvents like dichloromethane, chloroform

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    General Information
    Where to Buy 3-(4-Bromophenyl)pyridine in China?
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    Frequently Asked Questions

    As a leading 3-(4-Bromophenyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3- (4-bromophenyl) pyridine?
    3- (4-ether phenyl) groups are mainly used to play a key role in many fields. From the perspective of Tiangong Kaiji, such chemical groups have unique functions in the composition and reaction of substances.
    In the field of chemical synthesis, 3- (4-ether phenyl) groups are often used as key intermediates. Through delicate chemical reactions, they can be introduced into the molecular structure of a specific compound to change the physical and chemical properties of the compound. For example, in the preparation of polymer materials, the introduction of this group may enhance the stability and heat resistance of the material, making the prepared product more practical and durable.
    In the field of drug development, it also has a position that cannot be ignored. Due to the unique chemical structure and electronic properties of the 3 - (4 - ether phenyl) group, it may interact specifically with specific targets in organisms. Medicinal chemists can design and synthesize new drug molecules based on this group, hoping to achieve high-efficiency and low-toxicity therapeutic effects through its precise combination with the target.
    In addition, in the field of materials science, this group may have a significant impact on the optical and electrical properties of materials. In the design of new photoelectric materials, the rational use of 3- (4-ether phenyl) groups may endow the materials with special optical responses, such as fluorescence emission characteristics, so as to be applied to frontier scientific and technological fields such as Light Emitting Diodes and sensors.
    In summary, 3- (4-ether phenyl) groups have shown broad application prospects and important practical value in many fields such as chemical industry, medicine, and materials due to their unique chemical properties.
    What are the synthesis methods of 3- (4-bromophenyl) pyridine?
    There are many ways to synthesize 3- (4-benzyl) compounds. First, nucleophilic substitution can be used. Choose a suitable nucleophilic reagent, such as alkoxides, amines, etc., to interact with compounds containing halogenated benzyl groups. The activity of halogen atoms is quite high, and the nucleophilic reagents can attack the carbon atoms of benzyl groups. The halogen atoms leave, and then form the desired bond to obtain the target product. The reaction conditions need to be carefully regulated, such as temperature, solvent, etc., which have a significant impact on the reaction rate and yield.
    Second, the coupling reaction can be catalyzed by transition metals. For example, in the Suzuki coupling reaction catalyzed by palladium, aryl boronic acid and halogenated benzyl compounds are used as raw materials. In the presence of palladium catalyst, base and appropriate solvent, the two are coupled to form carbon-carbon bonds, and then the target molecule is synthesized. This method has good selectivity and can effectively construct complex molecular structures. However, it requires strict reaction conditions. The choice and dosage of catalysts, the type of base, etc. must be carefully considered.
    Furthermore, the reaction of carbonyl compounds can be used. If the target molecular structure is appropriate, the carbonyl compound can undergo condensation reaction with the benzyl-containing reagent. Such as formaldehyde or ketone and benzyl amine under acid or base catalysis, through nucleophilic addition-elimination process, to generate nitrogen-containing target products. In this process, the pH of the reaction medium, the ratio of reactants and other factors have a significant impact on the reaction process.
    In addition, free radical reaction can also be the way of synthesis. Free radicals are generated by initiators, so that benzyl radicals can be added to other free radicals or unsaturated bonds to construct the desired molecular skeleton. However, free radicals have high reactivity and slightly poor selectivity. Careful control of reaction conditions is required to obtain products with higher yield and purity.
    What are the physical properties of 3- (4-bromophenyl) pyridine?
    3- (4-cyanopyridine) is an organic compound, and its physical properties are as follows:
    ###Appearance and Properties
    At room temperature, 3- (4-cyanopyridine) usually appears as a white to light yellow crystalline powder. Its powder is fine in texture, and under light irradiation, tiny particles can be seen to shimmer. This appearance feature is helpful for preliminary identification and judgment in actual operation. It can be distinguished from other similar compounds by observing its color and state with the naked eye.
    ###Melting point and boiling point
    Melting point is in a certain temperature range, about [X] ° C. The melting point is one of the important physical properties of the substance. During the heating process, when this temperature is reached, 3- (4-cyanopyridine) will transform from a solid state to a liquid state. This transition process is of key significance in chemical analysis and substance identification. By accurately measuring the melting point, the purity of the substance can be verified. If the melting point deviates from the theoretical value, it indicates that its purity is high; conversely, if the deviation is large, it may contain impurities. The boiling point is about [X] ° C. The boiling point reflects the temperature conditions under which the substance changes from a liquid state to a gas state under a specific pressure. In the process of chemical production and separation and purification, according to the property of boiling point, 3- (4-cyanopyridine) can be separated from the mixture by distillation and other methods to realize the purification and purification of the substance.
    ###Solubility
    3- (4-cyanopyridine) has a certain solubility in a variety of common organic solvents. For example, it is soluble in organic solvents such as ethanol and acetone. In ethanol, its solubility will increase with the increase of temperature. This solubility enables it to be uniformly dispersed in a suitable solvent system as a reactant in the organic synthesis reaction, promoting the smooth progress of the reaction. At the same time, in the process of separation and purification, taking advantage of the difference in solubility in different solvents, methods such as recrystallization can be used to further improve the purity. However, its solubility in water is relatively small, which also affects its application and treatment in different environments.
    ##density
    Its density is [X] g/cm ³. As an inherent property of a substance, density has important reference value for determining its fluctuation in different media and distribution in the mixed system. In the process of material transportation and storage in chemical production, understanding density is helpful to rationally design the specifications of containers and the parameters of transportation pipelines to ensure the safety and efficiency of the production process.
    What is the price range of 3- (4-bromophenyl) pyridine in the market?
    Wen Jun's inquiry is about the price range of (4 - Poria cocos) in the city. Poria cocos are commonly used medicinal materials, and their price is in the city, depending on the quality of the product and the production.
    High-quality Poria cocos have a solid texture, fine powder, white and pure color. The price of such Poria cocos in the city is about one hundred and twenty to one hundred and eighty yuan per catty. Because of its excellent texture and good medicinal effect, the price is also high. It is mostly favored by pharmaceutical shops and wealthy families. It is used to make excellent medicines or is a choice for health care.
    Medium Poria cocos have good texture. Although they are not as pure and delicate as the best, they are still usable materials. Its price is about eighty to one hundred and twenty yuan per catty. These Poria cocos are quite common in general pharmacies and folk medicines. They can meet the needs of daily treatment and are widely used.
    The lower Poria cocos have a slightly inferior texture, or contain impurities, or have poor powder quality. Their price is about forty to eighty yuan per catty. It is mostly used for prescriptions that require a little less quality of medicinal materials, or simple treatments for ordinary people.
    The origin is different, and the price is also different. For example, Poria cocos produced in one place are of high quality due to suitable water and soil, and the price may be slightly higher than elsewhere. And the supply and demand of the city also affects its price. If the demand for Poria cocos is strong, the price may rise slightly; on the contrary, if the supply exceeds the demand, the price may float down.
    This is the approximate price range of Poria cocos in the city. The market conditions are changeable, and the price is also impermanent. It is for your reference only.
    How stable is 3- (4-bromophenyl) pyridine?
    The stability of Ximing (3- (4 -cyanopyridine)) requires detailed investigation of its structure and properties. Cyanopyridine is also a compound with cyano (-CN) and pyridine rings.
    In (3- (4 -cyanopyridine)), the pyridine ring is an aromatic six-membered heterocycle, and its electron cloud distribution is delocalized, which endows the structure with certain stability. Nitrogen atom in the pyridine ring, because its electronegativity is larger than that of carbon atom, causes the electron cloud to be biased towards nitrogen atom, so that the electron cloud density on the pyridine ring is uneven, and the electron cloud density on the adjacent and para-position is relatively low.
    In the cyanyl group (-CN), the carbon-nitrogen triple bond has high bond energy and is quite stable. However, the cyanyl group is a strong electron-absorbing group, and it also affects the electron cloud distribution of the pyridine ring through induction and conjugation effects.
    From the perspective of spatial structure, the substituent position of (3- (4-cyanopyridine)) may cause a certain steric hindrance. If the steric hindrance is too large, or the intramolecular tension increases, the stability decreases. However, in this compound, if the spatial arrangement of cyano and pyridine rings is moderate, the steric hindrance may not be the dominant factor.
    Furthermore, external environmental factors, such as temperature, humidity, light, and exposure to chemical substances, also play a role in its stability. At high temperatures, the thermal motion of molecules intensifies, or the vibration of chemical bonds increases. When it reaches a certain level, the chemical bonds are at risk of breaking and the stability decreases. In humid environments, if the compound has a hydrophilic check point or undergoes reactions such as hydrolysis, its stability is affected. Light or luminescent chemical reactions change the molecular structure.
    Overall, (3- (4-cyanopyridine)) has a certain inherent stability due to the aromatic properties of the pyridine ring and the stability of the cyano group. However, external factors are changeable, and actual stability requires comprehensive consideration of its specific environment and conditions.