2-thiophen-2-ylimidazo[1,2-a]pyridine

2 - (thiophene-2-yl) imidazolo [1,2-a] pyridine, this is an organic compound. It has a wide range of uses and has shown important value in many fields.
In the field of medicinal chemistry, such compounds are often used as potential drug molecules or lead compounds. Due to their unique chemical structure, they can interact with specific targets in organisms. Many studies have been devoted to exploring their biological activities, such as anti-tumor activity. Some studies have found that compounds with this structure can inhibit the proliferation of certain tumor cells, or induce tumor cell apoptosis, shining hope for the development of new anti-tumor drugs. In addition, it also has certain potential in antibacterial and antiviral aspects, or it can interfere with the key life activities of pathogens, so as to achieve the purpose of antibacterial and antiviral.
In the field of materials science, 2- (thiophene-2-yl) imidazolo [1,2-a] pyridine may be used as a cornerstone for the construction of new functional materials. Because of its special electronic structure and optical properties, it can be applied to the field of optoelectronic materials. For example, it is expected to prepare materials with unique luminescent properties for optoelectronic devices such as organic Light Emitting Diodes (OLEDs), which can help improve the luminous efficiency and stability of devices, thereby improving the performance of display technology and lighting technology.
In the field of organic synthetic chemistry, it is an important synthetic intermediate. With its specific reactivity check point, more complex organic molecular structures can be constructed through various organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. Organic chemists can use this as a starting material to design and synthesize organic compounds with different functions and structures, enrich the variety of organic compounds, and expand more possibilities for chemical research and practical applications.

2-Thiophene-2-ylimidazolo [1,2-a] pyridine is one of the organic compounds. Its physical properties are particularly important, and it is related to the performance of this compound in various situations.
Looking at its appearance, at room temperature and pressure, it is mostly in a white-like to light yellow solid form, just like coagulation, warm and has a unique color, which is easy to identify and operate. Its melting point is also a key property, about [X] ° C. When the temperature rises to this point, the substance gradually melts from the solid state, just like ice and snow melting when heated. This property is crucial in the experimental process of separation and purification, and its purity can be determined by the melting point.
In addition, the solubility is also an inescapable property. In organic solvents such as dichloromethane and chloroform, its solubility is quite good, just like fish getting water, and it is easy to blend. Due to the interaction between the molecular structure of the compound and the solvent, the two can be miscible. However, in solvents with strong polarity such as water, the solubility is very small, just like the difficulty of oil and water. This difference helps researchers choose suitable solvents according to their uses.
In addition, the density of 2-thiophene-2-ylimidazolo [1,2-a] pyridine is also fixed, about [X] g/cm ³. This value represents the weight of its unit volume. In practical applications such as measurement and storage, it provides accurate data basis to help researchers properly plan the use of materials.
And its stability is good under normal conditions. However, when encountering strong oxidizing agents and strong acids and alkalis, the structure is easily damaged, just like when a delicate flower encounters a violent storm. When storing and using, it is necessary to pay attention to environmental factors and avoid contact with such substances to ensure the integrity of the compound.

2-Thiophene-2-ylimidazolo [1,2-a] pyridine, this is an organic compound. Its chemical properties are unique, and it has the structural characteristics of both thiophene and imidazolo-pyridine, so it has its unique reactivity and physical properties.
From the perspective of reactivity, the sulfur atom on the thiophene ring has a solitary pair of electrons, which can participate in various electron cloud transfer reactions. The electron cloud density of the thiophene ring is high, and it often exhibits activity in electrophilic substitution reactions. Its 2-position is connected to imidazolo-pyridine, which may affect the distribution of molecular electron clouds and change the reaction check point and activity. For example, the electrophilic reagent or preferentially attack the specific position of imidazolopyridine affected by the electronic effect of the thiophene ring. Due to the power supply of the thiophene ring, the electron cloud density of the connected imidazolopyridine part changes, and some check points are more likely to attract electrophilic reagents.
The structure of imidazolo [1,2-a] pyridine also gives this compound unique properties. The imidazolopyridine system has a conjugate structure, which enhances molecular stability. This conjugate structure also affects its spectral properties. In the ultraviolet-visible spectrum, there may be specific absorption peaks, which can be used for qualitative and quantitative analysis.
Furthermore, the nitrogen atom of this compound has lone pairs of electrons, which can be used as a ligand to complex with metal ions to form This property may have applications in the field of catalysis. Metal complexes may exhibit unique catalytic activity to catalyze specific organic reactions.
In terms of physical properties, due to the aromatic ring structure in the molecule, the intermolecular force is mainly van der Waals force, or has a certain melting point and boiling point. Its solubility may be affected by molecular polarity. Although it contains nitrogen and sulfur heteroatoms, the overall aromatic structure is dominant, or its solubility is limited in polar organic solvents, and it is slightly better in non-polar or weakly polar organic solvents such as toluene and dichloromethane.
In summary, 2-thiophene-2-ylimidazolo [1,2-a] pyridine has a unique structure and rich chemical properties, which may have broad application prospects in the fields of organic synthesis, materials science, and coordination chemistry.

The synthesis method of 2-thiophene-2-ylimidazolo [1,2-a] pyridine has been known for a long time, and it follows the method of organic synthesis. The beginning of the synthesis of this compound is often based on thiophene and pyridine compounds.
At first, thiophene-2-formaldehyde is selected as the starting material, and it is combined with nitrogen-containing heterocyclic compounds, such as 2-aminopyridine, in a suitable reaction medium. The reaction medium is often organic solvents, such as ethanol and toluene, which can provide a suitable environment for the reaction and make the interaction between molecules smooth. < Br >
When reacting, add an appropriate amount of catalyst, this catalyst can increase the rate of reaction and promote the movement of its equilibrium. Common catalysts include acid catalysts, such as p-toluenesulfonic acid, or alkali catalysts, such as potassium carbonate. Choose carefully according to the reaction conditions and the characteristics of the substrate.
The reaction system needs to be controlled at an appropriate temperature. At low temperatures, the molecular activity is slightly weaker and the reaction is slow; at high temperatures, although the reaction rate can be increased, side reactions are also easy to occur. Therefore, the temperature is usually controlled between 80 and 120 ° C to achieve the best reaction effect. In this temperature range, the reactant molecules collide frequently, which is conducive to the breaking and formation of chemical bonds.
After the condensation reaction is completed, the product is often mixed with impurities, and needs to be separated and purified. First, by extraction, an organic solvent such as ethyl acetate is divided with an aqueous phase to enrich the product in the organic phase. After column chromatography, appropriate silica gel is selected as the stationary phase and eluted with different proportions of eluents to obtain purified 2-thiophene-2-ylimidazolo [1,2-a] pyridine. In this way, after several steps of reaction and purification, the target compound can be obtained. Although the synthesis method is complicated, it can be obtained according to this method.

Today there is a question, what is the price of 2-thiophen-2-ylimidazo [1,2-a] pyridine in the market? This is a specific compound in the field of fine chemicals, but the price in the market is difficult to determine.
covers the change in its price, subject to many reasons. First, the price of raw materials is very critical. If the raw materials required to synthesize this compound are scarce and expensive, such as specific sulfur-containing and nitrogen-containing raw materials, the cost will rise, which will inevitably lead to higher prices of finished products. Second, the complexity of the preparation process also affects. If you need to go through multi-step reactions, harsh reaction conditions, such as high temperature, high pressure, specific catalysts, etc., the process cost will increase and the price will also be high. Third, the supply and demand relationship in the market determines the price. If there is a strong demand for this compound in many industries, such as pharmaceutical research and development, material science and other fields, the demand exceeds the supply, the price will rise; on the contrary, if the supply exceeds the demand, the price will drop.
As far as I know, there is no exact price range to report at this time. Or due to the different difficulty of preparation and market demand, the price or difference between suppliers is quite large. If you want to know the exact price, you need to consult a professional chemical raw material supplier, or check it in detail on the chemical product trading platform to get a near-real price.