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What is the chemical structure of 2-Pyridinemethanol, 5-methoxy- (9CI)?
2-Pyridyl methanol, 5-methoxyl- (9CI), its chemical structure can also be deduced according to its name. "Pyridine" is a six-membered heterocyclic ring containing nitrogen. There are five carbon atoms and one nitrogen atom on the ring, forming a stable conjugated system. The base of "methanol", that is, -CH ² OH, is attached to the pyridine ring. This "2-pyridyl methanol", that is, the methanol group is attached to the 2-carbon of the pyridine ring.
Furthermore, "5-methoxy", this "methoxy group" is -OCH, and is attached to the 5-carbon of the pyridine ring. In summary, the structure of this compound is based on a pyridine ring, a methanol group at the 2-position carbon, and a methoxy group at the 5-position carbon. Its specific structure is depicted in symbols, the pyridine ring is depicted in hexagons, the nitrogen atom is placed in one corner of the ring, the 2-position carbon protrudes a -CH ² OH group, and the 5-position carbon is a -OCH 🥰 group. This is the chemical structure of 2-pyridine methanol, 5-methoxyl- (9CI).
What are the physical properties of 2-Pyridinemethanol, 5-methoxy- (9CI)?
2-Pyridyl methanol, 5-methoxyl- (9CI), is an organic compound. Its physical properties are quite important and relevant to its application in many fields.
Looking at its appearance, at room temperature and pressure, this substance is mostly white to light yellow crystalline powder, delicate and with a specific luster, like a delicate sand grain, flickering under light. Its color is pure and contains less variegation. This appearance characteristic is helpful for preliminary identification and purity judgment.
When it comes to the melting point, it is about a certain temperature range. This temperature range causes the substance to change from solid to liquid, such as the melting of mountain snow in the warm sun. The accurate determination of the melting point is of great significance in the identification and purification process, just like a precise beacon, guiding the direction of purification.
In terms of boiling point, under specific pressure conditions, the temperature at which a substance boils into a gaseous state is another key physical property. The value of the boiling point reflects the strength of the forces between the molecules of the substance, such as the toughness of the bond, which determines the morphological transformation of the substance in a high temperature environment.
Solubility is also an important physical property. This compound exhibits different solubility properties in common organic solvents such as ethanol and acetone. In ethanol, it is like a fish getting water, which can dissolve well and form a uniform and stable solution; in water, the solubility is relatively limited, just like oil droplets in water, which is difficult to blend. This difference in solubility provides a basis for operation in the process of separation, extraction and preparation of preparations.
Density is also a property that cannot be ignored. Under a specific temperature and pressure, its density imparts a specific weight and volume relationship to the substance, just like a measure of the "weight" of the substance, which is indispensable in quality control and product design.
In summary, the physical properties of 2-pyridylmethanol, 5-methoxyl- (9CI), from appearance to melting point, boiling point, solubility and density, are like a closely related chain. Each link is of great significance to the understanding and application of this substance, and is a key consideration in the research and production of chemical, pharmaceutical and other fields.
What are the main uses of 2-Pyridinemethanol, 5-methoxy- (9CI)?
2-Pyridyl methanol, 5-methoxyl- (9CI), this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize specific drugs. Through its unique chemical structure, it imparts specific activity and efficacy to drugs, or participates in the construction of drug molecules, which affects the pharmacological properties of drugs and helps to develop new drugs for the treatment of specific diseases. In the chemical field, it can be used to prepare special chemicals and materials. With its chemical properties, it plays a role in organic synthesis reactions and participates in the construction of complex organic compound structures. These compounds may have special properties, such as stability and solubility, and then be used in the manufacture of materials such as coatings and plastics. In scientific research and exploration, it is used as a chemical reagent to facilitate the study of organic chemistry. Researchers can gain in-depth insight into the mechanism of organic reactions and the properties of compounds by studying their chemical modifications and reactions, and contribute to the development of organic chemistry theory.
What are the preparation methods of 2-Pyridinemethanol, 5-methoxy- (9CI)?
The preparation of 2-pyridyl methanol, 5-methoxyl- (9CI) is an important method for organic synthesis. One method can be started from 5-methoxy-2-pyridyl carboxylic acid. First, a suitable reducing agent, such as lithium aluminum hydride, is slowly added to the reaction system containing 5-methoxy-2-pyridyl carboxylic acid at low temperature and in an anhydrous environment. Lithium aluminum hydride has strong reductive properties and can reduce carboxyl (-COOH) to hydroxymethyl (-CH 2O OH) to obtain the target product 2-pyridyl methanol, 5-methoxyl-. After the reaction, it is necessary to carefully handle the excess lithium aluminum hydride. Usually, water or dilute acid is carefully added dropwise to decompose it. After conventional post-treatment steps such as extraction, drying, and distillation, a pure product can be obtained.
Another method can be started with 5-methoxy-2-halogenated pyridine. Halogenated pyridine is reacted with magnesium metal to make a Grignard reagent. Then, the Grignard reagent is reacted with formaldehyde at low temperature. The carbon-magnesium bond in the Grignard reagent has strong nucleophilicity, which can attack the carbonyl carbon of formaldehyde. After hydrolysis, 2-pyridine methanol and 5-methoxyl- can also be obtained. In this process, the control of reaction temperature, reagent dosage and reaction time is very critical, and there is a slight difference in the pool, or side reactions may occur. After the preparation is completed, the steps of separation and purification are also required to obtain high-purity products. Both of these are effective paths for the preparation of 2-pyridyl methanol and 5-methoxy group.
2-Pyridinemethanol, 5-methoxy- (9CI) What are the precautions during storage and transportation?
2-Pyridyl methanol, 5-methoxyl- (9CI) During storage and transportation, many matters need to be paid attention to.
When storing it, the first environment. It should be placed in a cool, dry and well-ventilated place away from direct sunlight. This is due to light or cause the properties of the substance to change, such as triggering a decomposition reaction, which damages its purity and quality. Temperature is also critical. Excessive temperature may accelerate the volatilization of the substance, and even cause its chemical structure to change. Too low temperature or crystallization, solidification, etc., affect subsequent use.
Furthermore, storage containers should also be considered. When using containers with good corrosion resistance and sealing. Due to its chemical properties or reaction with certain materials, it is essential to choose a suitable container to ensure the stability of the substance and avoid leakage and deterioration.
When transporting, safety is the most important. Relevant transportation regulations and standards must be followed. Because of its possible danger, it must be properly fixed during transportation to prevent collision and vibration to avoid leakage caused by damage to the container. And transportation personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. If there is a leak during transportation, it must be dealt with immediately according to established procedures to evacuate the surrounding personnel and prevent the expansion of the hazard.
In addition, whether it is stored or transported, it should be well marked. Clearly label the name, characteristics, hazard warnings and other information of the substance so that personnel can identify and respond, and ensure the safety of the whole process.