2 Pyridinemethanol 5 Fluoro
pyridine pyrrole pyrazine piperidine piperazine

2-pyridinemethanol, 5-fluoro-

    Specifications

    HS Code

    988422

    Chemical Formula C6H6FNO
    Molecular Weight 127.116 g/mol
    Appearance Solid (likely white or off - white)
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Density Data may vary, needs experimental determination
    Solubility In Water Limited solubility (amine and fluorine groups affect polarity)
    Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol, acetone
    Pka Data may vary, related to the basicity of the pyridine nitrogen
    Stability Stable under normal conditions, may react with strong oxidizing or reducing agents
    Flash Point Data may vary, needs experimental determination

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    General Information
    Where to Buy 2-pyridinemethanol, 5-fluoro- in China?
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    Frequently Asked Questions

    As a leading 2-pyridinemethanol, 5-fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-pyridinemethanol, 5-fluoro-?
    2-Pyridyl methanol, 5-fluorine, this substance has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many special drugs. It may help to create novel therapies for specific diseases, and play an important cornerstone role in the research and development path of cutting-edge medicines such as anti-depression and anti-tumor. With its unique chemical structure, it can precisely connect with specific targets in organisms, providing new opportunities for disease treatment.
    In the field of chemical synthesis, it is an important raw material for the preparation of high-end fine chemicals. Through a series of delicate chemical reactions, it can be converted into materials with special properties, such as high-performance polymer additives, which can significantly improve the stability and durability of materials. It is used in aerospace, automotive manufacturing and other industries that require strict material properties.
    As an indispensable chemical reagent in the path of scientific research and exploration, it helps scientists to delve deeper into the mechanism and reaction path of organic synthesis. Its existence provides a powerful tool for unlocking many chemical mysteries, promoting the continuous expansion and extension of chemistry to unknown fields, and laying the groundwork for future scientific and technological breakthroughs.
    What are the physical properties of 2-pyridinemethanol, 5-fluoro-
    2-Pyridyl methanol, 5-fluoride, the properties of this substance are very different, let me be your detailed table.
    Its shape or crystalline state, the color is white, just like frost and snow, the appearance is pure and uniform, shining in the sun, exuding a unique crystal luster. At room temperature, it is as stable as a rock, but when exposed to high temperature, it is like ice and snow meeting the sun, gradually melting, and its melting point can be accurately measured. This is one of the criteria for judging its purity.
    As for solubility, it is also very interesting. In the medium of water, it is like a swimming fish entering the water, with a certain degree of solubility, but it is not completely integrated, and it seems to be in a delicate balance with water. In the context of organic solvents, such as alcohols and ethers, it is more friendly and can be integrated with solvents, just like water and emulsion. The characteristics of solubility are of crucial significance in its extraction, separation and application.
    Its density, compared with ordinary substances, has its unique value. For example, the key to weighing the weight is related to its distribution and behavior in various systems. Just like things have their own positions, the density is different, which determines their ups and downs and movements in different environments.
    Furthermore, its chemical activity cannot be ignored. Due to the structure of fluorine atoms and pyridine rings, it is like a sharp blade, giving it unique reactivity. On the stage of many chemical reactions, it can dance with a variety of reagents, or nucleophilic substitution, or oxidation reduction, all of which show extraordinary chemical charm, providing endless possibilities and imagination for the field of organic synthesis.
    This is the summary of the physical properties of 2-pyridyl methanol and 5-fluoride. Although it is simple, it can also be seen in the leopard.
    What are the chemical properties of 2-pyridinemethanol, 5-fluoro-
    2-Pyridyl methanol, 5-fluoro-, this substance has unique chemical properties. Its appearance is often colorless to slightly yellow liquid or solid, because it will have different aggregation states under different conditions.
    When it comes to solubility, it has good solubility in organic solvents such as ethanol and ether, just like fish get water, due to the adaptation of intermolecular forces. However, it is slightly less soluble in water, just like fish out of water, it is difficult to swim, because its molecular structure has limited interaction with water molecules.
    5-fluoro-2-pyridyl methanol also has characteristics of chemical activity. The presence of pyridine rings gives it alkalinity, just like the characteristics of bases, and can react with acids, just like softness. The introduction of fluorine atoms changes the electron cloud density of the compound, and fluorine atoms have strong electronegativity, such as strong magnets attracting electrons, resulting in enhanced reactivity. For example, in nucleophilic substitution reactions, fluorine atoms can become leaving groups, just like a wanderer leaving home to embark on a reaction journey.
    At the same time, the presence of methanol groups allows the compound to participate in esterification reactions, etc., as if building a bridge for chemical changes. It can also complex with metal ions, just like dancing hand in hand with metal ions to form stable complexes, which may be useful in catalytic reactions and other fields. In conclusion, 5-fluoro-2-pyridyl methanol has rich and diverse chemical properties, and has potential application value in organic synthesis, medicinal chemistry and other fields, such as jade.
    What are the synthesis methods of 2-pyridinemethanol and 5-fluoro-?
    To prepare 2-pyridyl methanol and 5-fluorine, the method is as follows. Fluorine-containing pyridine derivatives are often used as starting materials and are obtained by reacting in several steps.
    One method is to first take an appropriate 5-fluoropyridine compound and react with a specific reagent to introduce the desired alcohol group. If 5-fluoropyridine is reacted with a halogenated hydrocarbon in the presence of a suitable base and solvent, the nucleophilic substitution reaction can first obtain a halogenated pyridine intermediate. This halogen atom has high activity and can interact with nucleophiles, such as water or alkoxides, to obtain alcohol groups through substitution, and then obtain 2-pyridyl methanol, the product of 5-fluorine. During the reaction, the temperature, reaction time and reagent dosage need to be strictly controlled to increase the yield and purity of the product.
    Another method can be started from 5-fluoropyridine-2-carboxylic acid. The carboxylic acid is first reduced, often with strong reducing agents such as lithium aluminum hydride, in a low temperature and anhydrous environment. Be careful to reduce the carboxyl group to an alcohol group to obtain the target product. In this process, the amount of reducing agent and the control of the reaction conditions are extremely critical, otherwise it is easy to cause excessive reduction or other side reactions, which will damage the quality of the product.
    Another method of catalytic hydrogenation is to use unsaturated esters or aldoxides containing 5-fluoropyridine as raw materials, select suitable catalysts, such as palladium, platinum and other supported catalysts, in a hydrogen atmosphere, under appropriate temperature and pressure conditions, to hydrogenate unsaturated bonds and reduce, and at the same time realize the formation of alcohol groups to obtain 2-pyridyl methanol and 5-fluorine. This catalytic hydrogenation method has the advantages of mild reaction conditions and good selectivity. However, the selection and recycling of catalysts also need to be carefully considered to reduce costs and increase efficiency.
    In which fields is 2-pyridinemethanol, 5-fluoro- used?
    2-Pyridyl methanol, 5-fluorine - This substance is useful in many fields. In the context of pharmaceutical research and development, it is often the key raw material for the creation of new drugs. Due to its special chemical structure, it can precisely fit with specific targets in organisms, or has various pharmacological activities such as antibacterial, anti-inflammatory and anti-tumor, which is of great help in the fight against difficult diseases.
    In the land of materials science, it can participate in the synthesis of special functional materials. After a specific reaction, it is integrated into a polymer, giving the material unique optical, electrical or mechanical properties, making the material stand out in electronic devices, optical instruments, etc.
    In the field of organic synthesis, it is an extremely important intermediate. Through various organic reactions, such as substitution, addition, etc., complex and diverse organic compounds can be derived, which expands a broad path for the development of organic synthetic chemistry and enriches the types and functions of compounds.
    In summary, 2-pyridyl methanol, 5-fluorine - play a key role in many important fields such as medicine, materials, and organic synthesis due to their unique chemical properties, and promote continuous progress and innovation in related fields.